Λεπτομέρειες βιβλιογραφικής εγγραφής
| Τίτλος: |
Safety of hepatitis E vaccine in pregnancy |
| Συγγραφείς: |
Fan Zhang, Guang Yang, Yuting Chen, Dongjuan Chen, Zuliang Shi, Jianbo Xia, Ling Wang |
| Πηγή: |
Virology Journal, Vol 23, Iss 1 (2026) |
| Στοιχεία εκδότη: |
BMC, 2026. |
| Έτος έκδοσης: |
2026 |
| Συλλογή: |
LCC:Infectious and parasitic diseases |
| Θεματικοί όροι: |
Infectious and parasitic diseases, RC109-216 |
| Περιγραφή: |
Abstract This comment discusses the critical public health challenge of hepatitis E in pregnancy and highlights the significant safety evidence gap for the HEV239 vaccine in this vulnerable group. Focusing on a landmark study from South Sudan by Nesbitt RC et al., we provide a critical appraisal of its findings, integrate them with prior evidence from clinical trials and animal studies, and discuss implications for vaccination policy in outbreak settings, particularly in fragile and conflict-affected contexts. The comment concludes that vaccination during pregnancy shows no detected increased risk of fetal loss, providing crucial real-world data to inform life-saving vaccination policies, while acknowledging remaining uncertainties. |
| Τύπος εγγράφου: |
article |
| Περιγραφή αρχείου: |
electronic resource |
| Γλώσσα: |
English |
| ISSN: |
1743-422X |
| Relation: |
https://doaj.org/toc/1743-422X |
| DOI: |
10.1186/s12985-026-03205-2 |
| Σύνδεσμος πρόσβασης: |
https://doaj.org/article/c9e1cb84a16d427693f2468e3eb4876c |
| Αριθμός Καταχώρησης: |
edsdoj.9e1cb84a16d427693f2468e3eb4876c |
| Βάση Δεδομένων: |
Directory of Open Access Journals |