Academic Journal
New approaches to rationale pharmacotherapy of trigeminal neuralgia based on personalized medicine principles
| Τίτλος: | New approaches to rationale pharmacotherapy of trigeminal neuralgia based on personalized medicine principles |
|---|---|
| Συγγραφείς: | V. V. Arkhipov, A. V. Sokolov, T. A. Rodina, D. L. Pozdnyakov, Е. А. Sокоvа |
| Πηγή: | Регуляторные исследования и экспертиза лекарственных средств, Vol 0, Iss 1, Pp 16-20 (2018) |
| Στοιχεία εκδότη: | Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’), 2018. |
| Έτος έκδοσης: | 2018 |
| Συλλογή: | LCC:Medicine (General) |
| Θεματικοί όροι: | невралгия тройничного нерва, терапевтический лекарственный мониторинг, антиконвульсант, персонализированная медицина, рациональная фармакотерапия, trigeminal neuralgia, therapeutic drug monitoring, anticonvulsant, personalized medicine, rational pharmacotherapy, Medicine (General), R5-920 |
| Περιγραφή: | Optimization of pharmacotherapy (selection of optimal doses and dosing intervals) is a major objective of clinical pharmacology. This objective may be achieved, in part, by implementation of modern pharmacokinetic approaches and the use of therapeutic drug monitoring that consists in selection of an appropriate dose level and dosing interval based on information about drug concentrations at certain timepoints. This is particularly important for drugs with a narrow therapeutic range. The authors of the article advocate the usefulness of therapeutic drug monitoring in treating exacerbation of trigeminal neuralgia with carbamazepin and evaluate practical relevance of development of a new phenotyping method that could be used to increase pharmacotherapy efficiency and safety. |
| Τύπος εγγράφου: | article |
| Περιγραφή αρχείου: | electronic resource |
| Γλώσσα: | Russian |
| ISSN: | 3034-3062 3034-3453 |
| Relation: | https://www.vedomostincesmp.ru/jour/article/view/21; https://doaj.org/toc/3034-3062; https://doaj.org/toc/3034-3453 |
| Σύνδεσμος πρόσβασης: | https://doaj.org/article/89c4a4cdcefb4a7da5055a76ea2100d5 |
| Αριθμός Καταχώρησης: | edsdoj.89c4a4cdcefb4a7da5055a76ea2100d5 |
| Βάση Δεδομένων: | Directory of Open Access Journals |
| ISSN: | 30343062 30343453 |
|---|