Low-level laser therapy in osteoarthritic pain: A narrative review with an approach to integrated clinical use

Bibliographic Details
Title: Low-level laser therapy in osteoarthritic pain: A narrative review with an approach to integrated clinical use
Authors: S.N. Hennessy, G.D. Corcoran
Source: Osteoarthritis and Cartilage Open, Vol 7, Iss 4, Pp 100685- (2025)
Publisher Information: Elsevier, 2025.
Publication Year: 2025
Collection: LCC:Diseases of the musculoskeletal system
Subject Terms: Low-level laser therapy, Osteoarthritic pain, Non-pharmacological pain management, Photobiomodulation, Diseases of the musculoskeletal system, RC925-935
Description: Objective: The authors examine how Low-level laser therapy (LLLT) can be used in osteoarthritis (OA) management. LLLT has not, as yet, been widely integrated into OA management, either as a stand-alone modality or in conjunction with standard treatments. Methods: A narrative review of meta-analyses and trials using LLLT in OA treatment was undertaken to establish how it may be used optimally in OA management. Pubmed, Google Scholar and Cochrane databases were interrogated to identify analyses and trials. Results: Meta-analysis and trial results are variable, but improvements of up to 14.23 ​mm are noted in VAS scores following use in knee osteoarthritis (Standardised Mean Difference (SMD) 95 ​% CI: 7.31:21.14), 13.7 ​mm in spinal disease (SMD 95 ​% CI: 9.72; 17.42) and 19.86 ​mm (SMD 95 ​% CI: 10.04:29.68) in cervical disease. Positive effects on function were documented, as was a reduction in use of analgesic medication. Integration of LLLT into OA management programmes produced additional improvements. The side-effect profile is excellent. Issues of trial size, comparability, dosing, and assessment of response, mean that further studies are required. Conclusions: We conclude that LLLT is useful in the management of OA pain, with benefits for stiffness and function. Use as an integral part of an OA management and rehabilitation plan appears to give additional benefits. LLLT has an excellent side effect profile and may reduce need for analgesic medication, making it a potentially valuable adjunct in OA pain management, especially at a time when adverse effects of pharmacological treatment are of increasing concern.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2665-9131
Relation: http://www.sciencedirect.com/science/article/pii/S2665913125001219; https://doaj.org/toc/2665-9131
DOI: 10.1016/j.ocarto.2025.100685
Access URL: https://doaj.org/article/ce76feef6cd546c1a0e3a78b86b49ecc
Accession Number: edsdoj.76feef6cd546c1a0e3a78b86b49ecc
Database: Directory of Open Access Journals
Description
ISSN:26659131
DOI:10.1016/j.ocarto.2025.100685