Λεπτομέρειες βιβλιογραφικής εγγραφής
| Τίτλος: |
Moving in the mesoscale: Understanding the mechanics of cytoskeletal molecular motors by combining mesoscale simulations with imaging |
| Συγγραφείς: |
Gravett, MSC, Cocking, RC, Curd, AP, Harlen, O, Leng, J, Muench, SP, Peckham, M, Read, DJ, Rogers, JF, Welch, RC, Harris, SA |
| Στοιχεία εκδότη: |
Wiley |
| Έτος έκδοσης: |
2022 |
| Συλλογή: |
White Rose Research Online (Universities of Leeds, Sheffield & York) |
| Περιγραφή: |
Rapid advances in experimental biophysical techniques are generating a wealth of information about the mechanical operation of the cellular cytoskeleton and its motors. However, each of these tools typically provides only a limited piece of a highly complex puzzle. There is a need to develop new computational tools that can integrate these data together into a central model. Here we discuss the experimental advances alongside the computational tools, and propose how these could be developed to successfully combine the emerging structural and dynamic experimental data on cytoskeletal motors. We consider examples of both single motors and arrays of motors within a biological cell. |
| Τύπος εγγράφου: |
article in journal/newspaper |
| Περιγραφή αρχείου: |
text |
| Γλώσσα: |
English |
| ISSN: |
1759-0884 |
| Relation: |
https://eprints.whiterose.ac.uk/id/eprint/177851/1/WIREs%20Comput%20Mol%20Sci%20-%202021%20-%20Gravett%20-%20Moving%20in%20the%20mesoscale%20%20Understanding%20the%20mechanics%20of%20cytoskeletal%20molecular.pdf; Gravett, MSC orcid.org/0000-0001-8351-7176 , Cocking, RC, Curd, AP orcid.org/0000-0002-3949-7523 et al. (8 more authors) (Cover date: May/June 2022) Moving in the mesoscale: Understanding the mechanics of cytoskeletal molecular motors by combining mesoscale simulations with imaging. Wiley Interdisciplinary Reviews: Computational Molecular Science, 12 (3). e1570. ISSN: 1759-0884 |
| Διαθεσιμότητα: |
https://eprints.whiterose.ac.uk/id/eprint/177851/ |
| Rights: |
cc_by_4 |
| Αριθμός Καταχώρησης: |
edsbas.FF6E32E |
| Βάση Δεδομένων: |
BASE |