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The IDENTIFY study: the investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer – a multicentre observational study

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Τίτλος: The IDENTIFY study: the investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer – a multicentre observational study
Συγγραφείς: Khadhouri S., Gallagher K. M., MacKenzie K. R., Shah T. T., Gao C., Moore S., Zimmermann E. F., Edison E., Jefferies M., Nambiar A., Mannas M. P., Lee T., Marra G., Lillaz B., Gomez Rivas J., Olivier J., Assmus M. A., Ucar T., Claps F., Boltri M., Burnhope T., Nkwam N., Tanasescu G., Boxall N. E., Downey A. P., Lal A. A., Anton-Juanilla M., Clarke H., Lau D. H. W., Gillams K., Crockett M., Nielsen M., Takwoingi Y., Chuchu N., O'Rourke J., MacLennan G., McGrath J. S., Kasivisvanathan V., Chaudry A., Sharma A., Bennett A., Ahmad A., Abroaf A., Suliman A. M., Lloyd A., McKay A., Wong A., Silva A., Schneider A., MacKay A., Knight A., Grigorakis A., Bdesha A., Nagle A., Cebola A., Dhanasekaran A. K., Kondza A., Barcelos A., Galosi A. B., Ebur A., Minervini A., Russell A., Webb A., Garcia de Jalon A., Desai A., Czech A. K., Mainwaring A., Adimonye A., Das A., Figueiredo A., Villers A., Leminski A., Chippagiri A., Yildirim A., Voulgaris A. M., Uzan A., Oo A. M. M., Younis A., Zelhof B., Mukhtar B., Ayres B., Challacombe B., Sherwood B., Ristau B., Lai B., Nellensteijn B., Schreiter B., Trombetta C., Dowling C., Hobbs C., Benitez C. A. E., Lebacle C., Ho C. W. Y., Ng C. -F., Mount C., Lam C. M., Blick C., Brown C., Gallegos C., Higgs C., Browne C., McCann C., Alonso C. P., Beder D., Cohen D., Gordon D., Wilby D., Hrouda D., Karsza D., Mak D., Martin-Way D., Suthaharan D., Patel D., Carrion D. M., Nyanhongo D., Bass E., Mains E., Chau E., Castillo E. C., Day E., Desouky E., Gaines E., Papworth E., Yuruk E., Kilic E., Dinneen E., Palagonia E., Xylinas E., Khawaja F., Cimarra F., Bardet F., Kum F., Peters F., Kovacs G., Hellawell G., Tasso G., Lam G., La Montagna G., Pizzuto G., Lenart G., Ozgur G., Bi H., Lyons H., Warren H., Ahmed H., Simpson H., Burden H., Gresty H., Pita H. R., Serag H., Kynaston H., Crawford-Smith H., Mostafid H., Otaola-Arca H., Fen Koo H., Ibrahim I., Ouzaid I., Puche-Sanz I., Tomaskovic I., Tinay I., Sahibzada I., Thangasamy I., Cadena I. R., Irani J., Udzik J., Brittain J., Catto J., Green J., Tweedle J., Hernando J. B., Leask J., Kalsi J., Frankel J., Toniolo J., Raman J. D., Courcier J., Kumaradeevan J., Clark J., Jones J., Teoh J. Y. -C., Iacovou J., Kelly J., Selph J. P., Aning J., Deeks J., Maw J., Herranz-Yague J. A., Nolazco J. I., Cozar-Olmo J. M., Bagley J., Jelski J., Norris J., Testa J., Meeks J., Hernandez J., Vasquez J. L., Randhawa K., Dhera K., Gronostaj K., Houlton K., Lehman K., Adasonla K., Brown K., Murtagh K., Mistry K., Davenport K., Kitamura K., Derbyshire L., Clarke L., Morton L., Martinez L., Goldsmith L., Paramore L., Cormier L., Dell'Atti L., Simmons L., Martinez-Pineiro L., Rico L., Chan L., Forster L., Ma L., Moore M., Gallego M. C., Freire M. J., Emberton M., Feneley M., Rivero M. V. M., Pirsa M., Talle M., Liew M., Trail M., Cooper M., Kulkarni M., Ager M., He M., Li M., Omran Breish M., Tarin M., Aldiwani M., Matanhelia M., Pasha M., Akalin M. K., Abdullah N., Hale N., Gadiyar N., Kocher N., Bullock N., Campain N., Pavan N., Al-Ibraheem N., Bhatt N., Bedi N., Shrotri N., Lobo N., Balderas O., Kouli O., Capoun O., Manjavacas P. O., Gontero P., Mariappan P., Marchinena P. G., Erotocritou P., Sweeney P., Planelles P., Acher P., Black P. C., Osei-Bonsu P. K., Ostergren P., Smith P., Willemse P. -P. M., Chlosta P. L., Ul Ain Q., Barratt R., Esler R., Khalid R., Hsu R., Stamirowski R., Mangat R., Cruz R., Ellis R., Adams R., Hessell R., Oomen R. J. A., McConkey R., Ritchie R., Jarimba R., Chahal R., Andres R. M., Hawkins R., David R., Manecksha R. P., Agrawal S., Hamid S. S., Deem S., Goonewardene S., Swami S. K., Hori S., Khan S., Inder S. M., Sangaralingam S., Marathe S., Raveenthiran S., Horie S., Sengupta S., Parson S., Parker S., Hawlina S., Williams S., Mazzoli S., Kata S. G., Lopes S. P., Ramos S., Rai S., Rintoul-Hoad S., O'Meara S., Morris S., Turner S., Venturini S., Almpanis S., Joniau S., Jain S., Mallett S., Nikles S., Yan S. S., Drake T., Toma T., Plo T. C., Bonnin T., Muilwijk T., Wollin T., Chu T. S. M., Appanna T., Brophy T., Ellul T., Austin T., Smrkolj T., Rowe T., Sukhu T., Patel T., Garg T., Caskurlu T., Bele U., Haroon U., Crespo-Atin V., Cortes V. P., Poves V. C., Gnanapragasam V., Gauhar V., During V., Kumar V., Fiala V., Mahmalji W., Lam W., Chin Y. F., Filtekin Y., Phan Y. C., Ibrahim Y., Glaser Z. A., Adwin Z., Qin Z., Zotter Z., Zainuddin Z.
Συνεισφορές: Khadhouri, S., Gallagher, K. M., Mackenzie, K. R., Shah, T. T., Gao, C., Moore, S., Zimmermann, E. F., Edison, E., Jefferies, M., Nambiar, A., Mannas, M. P., Lee, T., Marra, G., Lillaz, B., Gomez Rivas, J., Olivier, J., Assmus, M. A., Ucar, T., Claps, F., Boltri, M., Burnhope, T., Nkwam, N., Tanasescu, G., Boxall, N. E., Downey, A. P., Lal, A. A., Anton-Juanilla, M., Clarke, H., Lau, D. H. W., Gillams, K., Crockett, M., Nielsen, M., Takwoingi, Y., Chuchu, N., O'Rourke, J., Maclennan, G., Mcgrath, J. S., Kasivisvanathan, V., Chaudry, A., Sharma, A., Bennett, A., Ahmad, A., Abroaf, A., Suliman, A. M., Lloyd, A., Mckay, A., Wong, A., Silva, A., Schneider, A., Mackay, A., Knight, A., Grigorakis, A., Bdesha, A., Nagle, A., Cebola, A., Dhanasekaran, A. K., Kondza, A., Barcelos, A., Galosi, A. B., Ebur, A., Minervini, A., Russell, A., Webb, A., Garcia de Jalon, A., Desai, A., Czech, A. K., Mainwaring, A., Adimonye, A., Das, A., Figueiredo, A., Villers, A., Leminski, A., Chippagiri, A., Yildirim, A., Voulgaris, A. M., Uzan, A., Oo, A. M. M., Younis, A., Zelhof, B., Mukhtar, B., Ayres, B., Challacombe, B., Sherwood, B., Ristau, B., Lai, B., Nellensteijn, B., Schreiter, B., Trombetta, C., Dowling, C., Hobbs, C., Benitez, C. A. E., Lebacle, C., Ho, C. W. Y., Ng, C. -F., Mount, C., Lam, C. M., Blick, C., Brown, C., Gallegos, C., Higgs, C.
Έτος έκδοσης: 2021
Συλλογή: Università Politecnica delle Marche: IRIS
Θεματικοί όροι: bladder cancer, cancer prevalence, haematuria, hematuria, prostate cancer, renal cancer, upper tract urothelial cancer, urinary tract cancer, Adult, Aged, Female, Human, Kidney Neoplasm, Male, Middle Aged, Prospective Studie, Referral and Consultation, Ureteral Neoplasm, Urinary Bladder Neoplasms
Περιγραφή: Objective: To evaluate the contemporary prevalence of urinary tract cancer (bladder cancer, upper tract urothelial cancer [UTUC] and renal cancer) in patients referred to secondary care with haematuria, adjusted for established patient risk markers and geographical variation. Patients and Methods: This was an international multicentre prospective observational study. We included patients aged ≥16 years, referred to secondary care with suspected urinary tract cancer. Patients with a known or previous urological malignancy were excluded. We estimated the prevalence of bladder cancer, UTUC, renal cancer and prostate cancer; stratified by age, type of haematuria, sex, and smoking. We used a multivariable mixed-effects logistic regression to adjust cancer prevalence for age, type of haematuria, sex, smoking, hospitals, and countries. Results: Of the 11 059 patients assessed for eligibility, 10 896 were included from 110 hospitals across 26 countries. The overall adjusted cancer prevalence (n = 2257) was 28.2% (95% confidence interval [CI] 22.3–34.1), bladder cancer (n = 1951) 24.7% (95% CI 19.1–30.2), UTUC (n = 128) 1.14% (95% CI 0.77–1.52), renal cancer (n = 107) 1.05% (95% CI 0.80–1.29), and prostate cancer (n = 124) 1.75% (95% CI 1.32–2.18). The odds ratios for patient risk markers in the model for all cancers were: age 1.04 (95% CI 1.03–1.05; P < 0.001), visible haematuria 3.47 (95% CI 2.90–4.15; P < 0.001), male sex 1.30 (95% CI 1.14–1.50; P < 0.001), and smoking 2.70 (95% CI 2.30–3.18; P < 0.001). Conclusions: A better understanding of cancer prevalence across an international population is required to inform clinical guidelines. We are the first to report urinary tract cancer prevalence across an international population in patients referred to secondary care, adjusted for patient risk markers and geographical variation. Bladder cancer was the most prevalent disease. Visible haematuria was the strongest predictor for urinary tract cancer.
Τύπος εγγράφου: article in journal/newspaper
Γλώσσα: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/33991045; info:eu-repo/semantics/altIdentifier/wos/WOS:000693631300001; volume:128; issue:4; firstpage:440; lastpage:450; numberofpages:11; journal:BJU INTERNATIONAL; https://hdl.handle.net/11566/296889
DOI: 10.1111/bju.15483
Διαθεσιμότητα: https://hdl.handle.net/11566/296889
https://doi.org/10.1111/bju.15483
Rights: info:eu-repo/semantics/openAccess
Αριθμός Καταχώρησης: edsbas.D606F767
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  Data: The IDENTIFY study: the investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer – a multicentre observational study
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M.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Blick+C%2E%22&quot;&gt;Blick C.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Brown+C%2E%22&quot;&gt;Brown C.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Gallegos+C%2E%22&quot;&gt;Gallegos C.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Higgs+C%2E%22&quot;&gt;Higgs C.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Browne+C%2E%22&quot;&gt;Browne C.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22McCann+C%2E%22&quot;&gt;McCann C.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Alonso+C%2E+P%2E%22&quot;&gt;Alonso C. P.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Beder+D%2E%22&quot;&gt;Beder D.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Cohen+D%2E%22&quot;&gt;Cohen D.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Gordon+D%2E%22&quot;&gt;Gordon D.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Wilby+D%2E%22&quot;&gt;Wilby D.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Hrouda+D%2E%22&quot;&gt;Hrouda D.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Karsza+D%2E%22&quot;&gt;Karsza D.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Mak+D%2E%22&quot;&gt;Mak D.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Martin-Way+D%2E%22&quot;&gt;Martin-Way D.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Suthaharan+D%2E%22&quot;&gt;Suthaharan D.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Patel+D%2E%22&quot;&gt;Patel D.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Carrion+D%2E+M%2E%22&quot;&gt;Carrion D. 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C.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Day+E%2E%22&quot;&gt;Day E.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Desouky+E%2E%22&quot;&gt;Desouky E.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Gaines+E%2E%22&quot;&gt;Gaines E.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Papworth+E%2E%22&quot;&gt;Papworth E.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Yuruk+E%2E%22&quot;&gt;Yuruk E.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Kilic+E%2E%22&quot;&gt;Kilic E.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Dinneen+E%2E%22&quot;&gt;Dinneen E.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Palagonia+E%2E%22&quot;&gt;Palagonia E.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Xylinas+E%2E%22&quot;&gt;Xylinas E.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Khawaja+F%2E%22&quot;&gt;Khawaja F.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Cimarra+F%2E%22&quot;&gt;Cimarra F.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Bardet+F%2E%22&quot;&gt;Bardet F.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Kum+F%2E%22&quot;&gt;Kum F.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Peters+F%2E%22&quot;&gt;Peters F.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Kovacs+G%2E%22&quot;&gt;Kovacs G.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Hellawell+G%2E%22&quot;&gt;Hellawell G.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Tasso+G%2E%22&quot;&gt;Tasso G.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lam+G%2E%22&quot;&gt;Lam G.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22La+Montagna+G%2E%22&quot;&gt;La Montagna G.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Pizzuto+G%2E%22&quot;&gt;Pizzuto G.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lenart+G%2E%22&quot;&gt;Lenart G.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Ozgur+G%2E%22&quot;&gt;Ozgur G.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Bi+H%2E%22&quot;&gt;Bi H.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lyons+H%2E%22&quot;&gt;Lyons H.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Warren+H%2E%22&quot;&gt;Warren H.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Ahmed+H%2E%22&quot;&gt;Ahmed H.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Simpson+H%2E%22&quot;&gt;Simpson H.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Burden+H%2E%22&quot;&gt;Burden H.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Gresty+H%2E%22&quot;&gt;Gresty H.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Pita+H%2E+R%2E%22&quot;&gt;Pita H. R.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Serag+H%2E%22&quot;&gt;Serag H.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Kynaston+H%2E%22&quot;&gt;Kynaston H.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Crawford-Smith+H%2E%22&quot;&gt;Crawford-Smith H.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Mostafid+H%2E%22&quot;&gt;Mostafid H.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Otaola-Arca+H%2E%22&quot;&gt;Otaola-Arca H.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Fen+Koo+H%2E%22&quot;&gt;Fen Koo H.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Ibrahim+I%2E%22&quot;&gt;Ibrahim I.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Ouzaid+I%2E%22&quot;&gt;Ouzaid I.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Puche-Sanz+I%2E%22&quot;&gt;Puche-Sanz I.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Tomaskovic+I%2E%22&quot;&gt;Tomaskovic I.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Tinay+I%2E%22&quot;&gt;Tinay I.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Sahibzada+I%2E%22&quot;&gt;Sahibzada I.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Thangasamy+I%2E%22&quot;&gt;Thangasamy I.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Cadena+I%2E+R%2E%22&quot;&gt;Cadena I. R.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Irani+J%2E%22&quot;&gt;Irani J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Udzik+J%2E%22&quot;&gt;Udzik J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Brittain+J%2E%22&quot;&gt;Brittain J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Catto+J%2E%22&quot;&gt;Catto J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Green+J%2E%22&quot;&gt;Green J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Tweedle+J%2E%22&quot;&gt;Tweedle J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Hernando+J%2E+B%2E%22&quot;&gt;Hernando J. B.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Leask+J%2E%22&quot;&gt;Leask J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Kalsi+J%2E%22&quot;&gt;Kalsi J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Frankel+J%2E%22&quot;&gt;Frankel J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Toniolo+J%2E%22&quot;&gt;Toniolo J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Raman+J%2E+D%2E%22&quot;&gt;Raman J. D.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Courcier+J%2E%22&quot;&gt;Courcier J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Kumaradeevan+J%2E%22&quot;&gt;Kumaradeevan J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Clark+J%2E%22&quot;&gt;Clark J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Jones+J%2E%22&quot;&gt;Jones J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Teoh+J%2E+Y%2E+-C%2E%22&quot;&gt;Teoh J. Y. -C.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Iacovou+J%2E%22&quot;&gt;Iacovou J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Kelly+J%2E%22&quot;&gt;Kelly J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Selph+J%2E+P%2E%22&quot;&gt;Selph J. P.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Aning+J%2E%22&quot;&gt;Aning J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Deeks+J%2E%22&quot;&gt;Deeks J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Maw+J%2E%22&quot;&gt;Maw J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Herranz-Yague+J%2E+A%2E%22&quot;&gt;Herranz-Yague J. A.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Nolazco+J%2E+I%2E%22&quot;&gt;Nolazco J. I.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Cozar-Olmo+J%2E+M%2E%22&quot;&gt;Cozar-Olmo J. M.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Bagley+J%2E%22&quot;&gt;Bagley J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Jelski+J%2E%22&quot;&gt;Jelski J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Norris+J%2E%22&quot;&gt;Norris J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Testa+J%2E%22&quot;&gt;Testa J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Meeks+J%2E%22&quot;&gt;Meeks J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Hernandez+J%2E%22&quot;&gt;Hernandez J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Vasquez+J%2E+L%2E%22&quot;&gt;Vasquez J. L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Randhawa+K%2E%22&quot;&gt;Randhawa K.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Dhera+K%2E%22&quot;&gt;Dhera K.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Gronostaj+K%2E%22&quot;&gt;Gronostaj K.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Houlton+K%2E%22&quot;&gt;Houlton K.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lehman+K%2E%22&quot;&gt;Lehman K.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Adasonla+K%2E%22&quot;&gt;Adasonla K.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Brown+K%2E%22&quot;&gt;Brown K.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Murtagh+K%2E%22&quot;&gt;Murtagh K.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Mistry+K%2E%22&quot;&gt;Mistry K.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Davenport+K%2E%22&quot;&gt;Davenport K.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Kitamura+K%2E%22&quot;&gt;Kitamura K.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Derbyshire+L%2E%22&quot;&gt;Derbyshire L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Clarke+L%2E%22&quot;&gt;Clarke L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Morton+L%2E%22&quot;&gt;Morton L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Martinez+L%2E%22&quot;&gt;Martinez L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Goldsmith+L%2E%22&quot;&gt;Goldsmith L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Paramore+L%2E%22&quot;&gt;Paramore L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Cormier+L%2E%22&quot;&gt;Cormier L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Dell&#39;Atti+L%2E%22&quot;&gt;Dell&#39;Atti L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Simmons+L%2E%22&quot;&gt;Simmons L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Martinez-Pineiro+L%2E%22&quot;&gt;Martinez-Pineiro L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Rico+L%2E%22&quot;&gt;Rico L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Chan+L%2E%22&quot;&gt;Chan L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Forster+L%2E%22&quot;&gt;Forster L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Ma+L%2E%22&quot;&gt;Ma L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Moore+M%2E%22&quot;&gt;Moore M.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Gallego+M%2E+C%2E%22&quot;&gt;Gallego M. C.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Freire+M%2E+J%2E%22&quot;&gt;Freire M. J.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Emberton+M%2E%22&quot;&gt;Emberton M.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Feneley+M%2E%22&quot;&gt;Feneley M.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Rivero+M%2E+V%2E+M%2E%22&quot;&gt;Rivero M. V. 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– Name: Author
  Label: Contributors
  Group: Au
  Data: Khadhouri, S.&lt;br /&gt;Gallagher, K. M.&lt;br /&gt;Mackenzie, K. R.&lt;br /&gt;Shah, T. T.&lt;br /&gt;Gao, C.&lt;br /&gt;Moore, S.&lt;br /&gt;Zimmermann, E. F.&lt;br /&gt;Edison, E.&lt;br /&gt;Jefferies, M.&lt;br /&gt;Nambiar, A.&lt;br /&gt;Mannas, M. P.&lt;br /&gt;Lee, T.&lt;br /&gt;Marra, G.&lt;br /&gt;Lillaz, B.&lt;br /&gt;Gomez Rivas, J.&lt;br /&gt;Olivier, J.&lt;br /&gt;Assmus, M. A.&lt;br /&gt;Ucar, T.&lt;br /&gt;Claps, F.&lt;br /&gt;Boltri, M.&lt;br /&gt;Burnhope, T.&lt;br /&gt;Nkwam, N.&lt;br /&gt;Tanasescu, G.&lt;br /&gt;Boxall, N. E.&lt;br /&gt;Downey, A. P.&lt;br /&gt;Lal, A. A.&lt;br /&gt;Anton-Juanilla, M.&lt;br /&gt;Clarke, H.&lt;br /&gt;Lau, D. H. W.&lt;br /&gt;Gillams, K.&lt;br /&gt;Crockett, M.&lt;br /&gt;Nielsen, M.&lt;br /&gt;Takwoingi, Y.&lt;br /&gt;Chuchu, N.&lt;br /&gt;O&#39;Rourke, J.&lt;br /&gt;Maclennan, G.&lt;br /&gt;Mcgrath, J. S.&lt;br /&gt;Kasivisvanathan, V.&lt;br /&gt;Chaudry, A.&lt;br /&gt;Sharma, A.&lt;br /&gt;Bennett, A.&lt;br /&gt;Ahmad, A.&lt;br /&gt;Abroaf, A.&lt;br /&gt;Suliman, A. M.&lt;br /&gt;Lloyd, A.&lt;br /&gt;Mckay, A.&lt;br /&gt;Wong, A.&lt;br /&gt;Silva, A.&lt;br /&gt;Schneider, A.&lt;br /&gt;Mackay, A.&lt;br /&gt;Knight, A.&lt;br /&gt;Grigorakis, A.&lt;br /&gt;Bdesha, A.&lt;br /&gt;Nagle, A.&lt;br /&gt;Cebola, A.&lt;br /&gt;Dhanasekaran, A. K.&lt;br /&gt;Kondza, A.&lt;br /&gt;Barcelos, A.&lt;br /&gt;Galosi, A. B.&lt;br /&gt;Ebur, A.&lt;br /&gt;Minervini, A.&lt;br /&gt;Russell, A.&lt;br /&gt;Webb, A.&lt;br /&gt;Garcia de Jalon, A.&lt;br /&gt;Desai, A.&lt;br /&gt;Czech, A. K.&lt;br /&gt;Mainwaring, A.&lt;br /&gt;Adimonye, A.&lt;br /&gt;Das, A.&lt;br /&gt;Figueiredo, A.&lt;br /&gt;Villers, A.&lt;br /&gt;Leminski, A.&lt;br /&gt;Chippagiri, A.&lt;br /&gt;Yildirim, A.&lt;br /&gt;Voulgaris, A. M.&lt;br /&gt;Uzan, A.&lt;br /&gt;Oo, A. M. M.&lt;br /&gt;Younis, A.&lt;br /&gt;Zelhof, B.&lt;br /&gt;Mukhtar, B.&lt;br /&gt;Ayres, B.&lt;br /&gt;Challacombe, B.&lt;br /&gt;Sherwood, B.&lt;br /&gt;Ristau, B.&lt;br /&gt;Lai, B.&lt;br /&gt;Nellensteijn, B.&lt;br /&gt;Schreiter, B.&lt;br /&gt;Trombetta, C.&lt;br /&gt;Dowling, C.&lt;br /&gt;Hobbs, C.&lt;br /&gt;Benitez, C. A. E.&lt;br /&gt;Lebacle, C.&lt;br /&gt;Ho, C. W. Y.&lt;br /&gt;Ng, C. -F.&lt;br /&gt;Mount, C.&lt;br /&gt;Lam, C. M.&lt;br /&gt;Blick, C.&lt;br /&gt;Brown, C.&lt;br /&gt;Gallegos, C.&lt;br /&gt;Higgs, C.
– Name: DatePubCY
  Label: Publication Year
  Group: Date
  Data: 2021
– Name: Subset
  Label: Collection
  Group: HoldingsInfo
  Data: Universit&#224; Politecnica delle Marche: IRIS
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22bladder+cancer%22&quot;&gt;bladder cancer&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22cancer+prevalence%22&quot;&gt;cancer prevalence&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22haematuria%22&quot;&gt;haematuria&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22hematuria%22&quot;&gt;hematuria&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22prostate+cancer%22&quot;&gt;prostate cancer&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22renal+cancer%22&quot;&gt;renal cancer&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22upper+tract+urothelial+cancer%22&quot;&gt;upper tract urothelial cancer&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22urinary+tract+cancer%22&quot;&gt;urinary tract cancer&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Adult%22&quot;&gt;Adult&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Aged%22&quot;&gt;Aged&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Female%22&quot;&gt;Female&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Human%22&quot;&gt;Human&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Kidney+Neoplasm%22&quot;&gt;Kidney Neoplasm&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Male%22&quot;&gt;Male&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Middle+Aged%22&quot;&gt;Middle Aged&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Prospective+Studie%22&quot;&gt;Prospective Studie&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Referral+and+Consultation%22&quot;&gt;Referral and Consultation&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Ureteral+Neoplasm%22&quot;&gt;Ureteral Neoplasm&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Urinary+Bladder+Neoplasms%22&quot;&gt;Urinary Bladder Neoplasms&lt;/searchLink&gt;
– Name: Abstract
  Label: Description
  Group: Ab
  Data: Objective: To evaluate the contemporary prevalence of urinary tract cancer (bladder cancer, upper tract urothelial cancer [UTUC] and renal cancer) in patients referred to secondary care with haematuria, adjusted for established patient risk markers and geographical variation. Patients and Methods: This was an international multicentre prospective observational study. We included patients aged ≥16 years, referred to secondary care with suspected urinary tract cancer. Patients with a known or previous urological malignancy were excluded. We estimated the prevalence of bladder cancer, UTUC, renal cancer and prostate cancer; stratified by age, type of haematuria, sex, and smoking. We used a multivariable mixed-effects logistic regression to adjust cancer prevalence for age, type of haematuria, sex, smoking, hospitals, and countries. Results: Of the 11 059 patients assessed for eligibility, 10 896 were included from 110 hospitals across 26 countries. The overall adjusted cancer prevalence (n = 2257) was 28.2% (95% confidence interval [CI] 22.3–34.1), bladder cancer (n = 1951) 24.7% (95% CI 19.1–30.2), UTUC (n = 128) 1.14% (95% CI 0.77–1.52), renal cancer (n = 107) 1.05% (95% CI 0.80–1.29), and prostate cancer (n = 124) 1.75% (95% CI 1.32–2.18). The odds ratios for patient risk markers in the model for all cancers were: age 1.04 (95% CI 1.03–1.05; P &lt; 0.001), visible haematuria 3.47 (95% CI 2.90–4.15; P &lt; 0.001), male sex 1.30 (95% CI 1.14–1.50; P &lt; 0.001), and smoking 2.70 (95% CI 2.30–3.18; P &lt; 0.001). Conclusions: A better understanding of cancer prevalence across an international population is required to inform clinical guidelines. We are the first to report urinary tract cancer prevalence across an international population in patients referred to secondary care, adjusted for patient risk markers and geographical variation. Bladder cancer was the most prevalent disease. Visible haematuria was the strongest predictor for urinary tract cancer.
– Name: TypeDocument
  Label: Document Type
  Group: TypDoc
  Data: article in journal/newspaper
– Name: Language
  Label: Language
  Group: Lang
  Data: English
– Name: NoteTitleSource
  Label: Relation
  Group: SrcInfo
  Data: info:eu-repo/semantics/altIdentifier/pmid/33991045; info:eu-repo/semantics/altIdentifier/wos/WOS:000693631300001; volume:128; issue:4; firstpage:440; lastpage:450; numberofpages:11; journal:BJU INTERNATIONAL; https://hdl.handle.net/11566/296889
– Name: DOI
  Label: DOI
  Group: ID
  Data: 10.1111/bju.15483
– Name: URL
  Label: Availability
  Group: URL
  Data: https://hdl.handle.net/11566/296889&lt;br /&gt;https://doi.org/10.1111/bju.15483
– Name: Copyright
  Label: Rights
  Group: Cpyrght
  Data: info:eu-repo/semantics/openAccess
– Name: AN
  Label: Accession Number
  Group: ID
  Data: edsbas.D606F767
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsbas&AN=edsbas.D606F767
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/bju.15483
    Languages:
      – Text: English
    Subjects:
      – SubjectFull: bladder cancer
        Type: general
      – SubjectFull: cancer prevalence
        Type: general
      – SubjectFull: haematuria
        Type: general
      – SubjectFull: hematuria
        Type: general
      – SubjectFull: prostate cancer
        Type: general
      – SubjectFull: renal cancer
        Type: general
      – SubjectFull: upper tract urothelial cancer
        Type: general
      – SubjectFull: urinary tract cancer
        Type: general
      – SubjectFull: Adult
        Type: general
      – SubjectFull: Aged
        Type: general
      – SubjectFull: Female
        Type: general
      – SubjectFull: Human
        Type: general
      – SubjectFull: Kidney Neoplasm
        Type: general
      – SubjectFull: Male
        Type: general
      – SubjectFull: Middle Aged
        Type: general
      – SubjectFull: Prospective Studie
        Type: general
      – SubjectFull: Referral and Consultation
        Type: general
      – SubjectFull: Ureteral Neoplasm
        Type: general
      – SubjectFull: Urinary Bladder Neoplasms
        Type: general
    Titles:
      – TitleFull: The IDENTIFY study: the investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer – a multicentre observational study
        Type: main
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