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Effects of parenteral nutrition + best supportive nutritional care vs. best supportive nutritional care alone on quality of life in patients with pancreatic cancer—a secondary analysis of PANUSCO

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Effects of parenteral nutrition + best supportive nutritional care vs. best supportive nutritional care alone on quality of life in patients with pancreatic cancer—a secondary analysis of PANUSCO
Συγγραφείς: Emanuel, Aline, Rosenberger, Friederike, Krampitz, Julia, Decker-Baumann, Christiane, Märten, Angela, Jäger, Dirk, Rötzer, Ingeborg
Πηγή: http://lobid.org/resources/99370678536206441#!, 32(7):466.
Έτος έκδοσης: 2024
Συλλογή: Publisso (ZB MED-Publikationsportal Lebenswissenschaften)
Θεματικοί όροι: QLQ-C30, Female [MeSH], Aged [MeSH], Humans [MeSH], QLQ-PAN26, Middle Aged [MeSH], Pancreatic Neoplasms/psychology [MeSH], Parenteral nutrition, Parenteral Nutrition/methods [MeSH], Quality of life, Male [MeSH], Pancreatic Neoplasms/therapy [MeSH], Quality of Life [MeSH], Research, Nutritional Status [MeSH], Nutritional Support/methods [MeSH], Pancreatic cancer
Περιγραφή: Abstract Purpose Parenteral nutrition (PN) can be an effective treatment to improve the nutritional status of patients with pancreatic cancer, but the effects of PN on quality of life (QoL) are still understudied. Therefore, we aimed at investigating whether the best supportive nutritional care (BSNC) in combination with PN at home compared to BSNC alone changed QoL in patients with advanced pancreatic cancer undergoing chemotherapy over a period of 7 weeks. Methods n = 12 patients in the PANUSCO study received nutritional counseling only (control group (CG)) and n = 9 patients were also given supportive PN (intervention group (IG)). The primary endpoint was the change of QoL (EORTC-QLQ-C30 and QLQ-PAN26) over 7 weeks between the groups. Results There was a significant worsening in social functioning in IG (p = 0.031) and a significant difference between groups in change of social functioning (p = 0.020). In all other domains of QoL, there was no significant difference between groups. Within groups, there was a significant improvement in the domain weight loss in IG (p = 0.031), showing that patients were less worried about their weight being too low. Furthermore, there was a significant difference in the change of BW over time between groups (p < 0.001) with IG showing an increase (p = 0.004) and CG showing no change (p = 0.578). ...
Τύπος εγγράφου: article in journal/newspaper
Γλώσσα: English
Relation: https://repository.publisso.de/resource/frl:6500795; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11211116/
DOI: 10.1007/s00520-024-08666-1
Διαθεσιμότητα: https://repository.publisso.de/resource/frl:6500795
https://doi.org/10.1007/s00520-024-08666-1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11211116/
Rights: https://creativecommons.org/licenses/by/4.0/
Αριθμός Καταχώρησης: edsbas.D47A6F07
Βάση Δεδομένων: BASE
Περιγραφή
DOI:10.1007/s00520-024-08666-1