Academic Journal
Phytochemicals in Helicobacter pylori infections: What are we doing now?
| Title: | Phytochemicals in Helicobacter pylori infections: What are we doing now? |
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| Authors: | Salehi, B, Sharopov, F, Martorell, M, Rajkovic, J, Ademiluyi, A, Sharifi-Rad, M, Fokou, P, Martins, N, Iriti, M, Sharifi-Rad, J |
| Contributors: | Instituto de Investigação e Inovação em Saúde |
| Publisher Information: | MDPI |
| Publication Year: | 2018 |
| Collection: | Repositório Aberto da Universidade do Porto |
| Subject Terms: | Animals, Bacterial Proteins/ antagonists & inhibitors, Bacterial Proteins / metabolismo, Helicobacter Infections/drug therapy, Helicobacter Infections / enzymology, Helicobacter Infections / pathology, Helicobacter pylori/enzymology, Humans, Phytotherapy, Plant Extracts/ therapeutic use, Urease/ antagonists & inhibitors, Urease / metabolism |
| Description: | In this critical review, plant sources used as effective antibacterial agents against Helicobacter pylori infections are carefully described. The main intrinsic bioactive molecules, responsible for the observed effects are also underlined and their corresponding modes of action specifically highlighted. In addition to traditional uses as herbal remedies, in vitro and in vivo studies focusing on plant extracts and isolated bioactive compounds with anti-H. pylori activity are also critically discussed. Lastly, special attention was also given to plant extracts with urease inhibitory effects, with emphasis on involved modes of action. ; Acknowledgments: N. Martins would like to thank the Portuguese Foundation for Science and Technology (FCT–Portugal) for the Strategic project ref. UID/BIM/04293/2013 and “NORTE2020—Programa Operacional Regional do Norte” (NORTE-01-0145-FEDER-000012). |
| Document Type: | article in journal/newspaper |
| File Description: | application/pdf |
| Language: | English |
| Relation: | info:eu-repo/grantAgreement/FCT/5876/147342/PT; International Journal of Molecular Sciences, vol.19(8)):2361; https://www.mdpi.com/1422-0067/19/8/2361; https://hdl.handle.net/10216/127037 |
| DOI: | 10.3390/ijms19082361 |
| Availability: | https://hdl.handle.net/10216/127037 https://doi.org/10.3390/ijms19082361 |
| Rights: | info:eu-repo/semantics/openAccess |
| Accession Number: | edsbas.B583FD36 |
| Database: | BASE |
| DOI: | 10.3390/ijms19082361 |
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