Academic Journal
Voltammetric studies of the effect of Cisplatin-liposome on Hela cells
| Τίτλος: | Voltammetric studies of the effect of Cisplatin-liposome on Hela cells |
|---|---|
| Συγγραφείς: | Ci, YX, Zhai, Q, Wang, S, Chang, WB, Zhang, CY, Ma, H, Chen, DY, Zhao, MZ, Hu, SW |
| Συνεισφορές: | Ci, YX (reprint author), Peking Univ, Coll Chem & Mol Engn, Dept Chem, Beijing 100871, Peoples R China., Peking Univ, Coll Chem & Mol Engn, Dept Chem, Beijing 100871, Peoples R China., Tsing Hua Univ, Dept Phys, Beijing 100084, Peoples R China., Inst Noble Met, Kunming, Peoples R China. |
| Πηγή: | EI ; SCI ; PubMed |
| Στοιχεία εκδότη: | talanta |
| Έτος έκδοσης: | 2001 |
| Συλλογή: | Peking University Institutional Repository (PKU IR) / 北京大学机构知识库 |
| Θεματικοί όροι: | Cisplatin-liposome, Hela cells, voltammetry, DNA |
| Περιγραφή: | In this paper, the voltammetric method was used for the first time to study the effect of Cisplatin-liposome on Hela cells. The results showed the voltammetric behavior of Hela cells was irreversible and the peak current had linear relationship with the cell number. With both Cisplatin-liposome concentration and treating time increasing, the peak current decreased. The peak current decreasing was in accordance with the nuclear damage and loss of mitochondrial membrane potential revealed by two-photon laser scanning microscopy and confocal laser scanning microscopy. This voltammetric method may provide a simple way to study the electron-transfer mechanism in drug-treating cells. (C) 2001 Elsevier Science B.V. All rights reserved. ; Chemistry, Analytical ; SCI(E) ; EI ; PubMed ; 10 ; ARTICLE ; 4 ; 693-698 ; 55 |
| Τύπος εγγράφου: | journal/newspaper |
| Γλώσσα: | English |
| ISBN: | 978-0-00-173288-9 0-00-173288-9 |
| Relation: | 672051; https://hdl.handle.net/20.500.11897/150188; WOS:000173288900005 |
| DOI: | 10.1016/S0039-9140(01)00480-5 |
| Διαθεσιμότητα: | https://hdl.handle.net/20.500.11897/150188 https://doi.org/10.1016/S0039-9140(01)00480-5 |
| Αριθμός Καταχώρησης: | edsbas.B39C3625 |
| Βάση Δεδομένων: | BASE |
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