Academic Journal
Efficacy of interventions for myopia control in children:A systematic review with network meta-analyses
| Τίτλος: | Efficacy of interventions for myopia control in children:A systematic review with network meta-analyses |
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| Συγγραφείς: | Schmidt, Diana Chabané, Hvid-Hansen, Anders, Jacobsen, Nina, Jakobsen, Trine Møldrup, Larsen, Per Michael, Lindblad, Kjersti Kristin, Møller, Flemming, Slyngborg, Annette, Subhi, Yousif, Kessel, Line |
| Πηγή: | Schmidt, D C, Hvid-Hansen, A, Jacobsen, N, Jakobsen, T M, Larsen, P M, Lindblad, K K, Møller, F, Slyngborg, A, Subhi, Y & Kessel, L 2025, 'Efficacy of interventions for myopia control in children : A systematic review with network meta-analyses', Acta Ophthalmologica, vol. 103, no. 8, pp. 939-965. https://doi.org/10.1111/aos.17496 |
| Έτος έκδοσης: | 2025 |
| Συλλογή: | University of Southern Denmark: Research Output / Syddansk Universitet |
| Θεματικοί όροι: | axial length, efficacy comparison, myopia control, network meta-analysis |
| Περιγραφή: | To determine the effectiveness of various interventions in reducing myopia progression in children. Literature databases were searched on December 2, 2023: PubMed, Embase, the Cochrane Central, Web of Science Core Collection, BIOSIS Previews, Current Contents Connect, Data Citation Index, Derwent Innovations Index, KCI-Korean Journal Database, Preprint Citation Index, ProQuest™ Dissertations and Theses Citation Index and SciELO Citation Index. PRISMA guidelines and the Cochrane Handbook recommendations were followed. All unique interventions were analyzed individually in order to generate clinically applicable results. The main outcome was axial length progression. Secondary outcomes were incident corneal infiltrates, photophobia, development of an allergic response towards the intervention, visual acuity at near and distance and drop-out from allocated intervention/control. We identified 74 RCTs involving 12 154 participants aged 6–18 years. Network meta-analysis compared axial length after 1 year between 45 interventions and placebo or single-vision spectacles. The most effective interventions reported in weighted mean difference and 95% confidence interval were low-level red-light (−0.33 mm (−0.40, −0.25)), ortho-K with 5 mm treatment zone (−0.32 mm (−0.41, −0.24)), ortho-K with aspheric base curve (−0.29 mm (−0.37, −0.22)), atropine 1.0% (−0.28 mm (−0.30, −0.26)), combined atropine 0.01% and ortho-K (−0.24 mm (−0.37, −0.11)), spectacles with highly aspherical lenslets (−0.23 mm (−0.26, −0.19)), ortho-K with increased compression factor (−0.23 mm (−0.28, −0.17), atropine 0.05% (−0.21 mm (−0.30, −0.13)) and defocus incorporated multiple segments spectacles (−0.21 mm (−0.27, −0.15)). Photophobia and reduced near-visual acuity were reported for atropine, and lower adherence to treatment was found for atropine at 1.0%. There was no significant association between any interventions and corneal infiltrates or allergic reactions. Over 70% of the studies were conducted in Asian populations. This systematic review and ... |
| Τύπος εγγράφου: | article in journal/newspaper |
| Περιγραφή αρχείου: | application/pdf |
| Γλώσσα: | English |
| ISSN: | 1755-375X 1755-3768 |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/40219611; info:eu-repo/semantics/altIdentifier/pissn/1755-375X; info:eu-repo/semantics/altIdentifier/eissn/1755-3768 |
| DOI: | 10.1111/aos.17496 |
| Διαθεσιμότητα: | https://portal.findresearcher.sdu.dk/da/publications/80bd957a-900a-4f41-9877-711a8cc14df3 https://doi.org/10.1111/aos.17496 https://findresearcher.sdu.dk/ws/files/298731000/Open_Access_Version.pdf |
| Rights: | info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by-nc/4.0/ |
| Αριθμός Καταχώρησης: | edsbas.ACF5C133 |
| Βάση Δεδομένων: | BASE |
| ISSN: | 1755375X 17553768 |
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| DOI: | 10.1111/aos.17496 |