Academic Journal
Metabolic syndrome in adults with autistic traits: associated psychological, behavioral, and biological factors in females and males – a PharmLines initiative
| Τίτλος: | Metabolic syndrome in adults with autistic traits: associated psychological, behavioral, and biological factors in females and males – a PharmLines initiative |
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| Συγγραφείς: | Warreman, E.B., Nooteboom, L.A., Leenen, P.J.M., Geurts, H.M., Terry, M.B., Bos, J.H.J., Hak, E., Hoek, H.W., van Rossum, E.F.C., Vermeiren, R.R.J.M., Ester, W.A. |
| Πηγή: | Warreman, E B, Nooteboom, L A, Leenen, P J M, Geurts, H M, Terry, M B, Bos, J H J, Hak, E, Hoek, H W, van Rossum, E F C, Vermeiren, R R J M & Ester, W A 2023, 'Metabolic syndrome in adults with autistic traits: associated psychological, behavioral, and biological factors in females and males – a PharmLines initiative', Frontiers in Psychiatry, vol. 14, 1303840. https://doi.org/10.3389/fpsyt.2023.1303840 |
| Έτος έκδοσης: | 2023 |
| Συλλογή: | Universiteit van Amsterdam: Digital Academic Repository (UvA DARE) |
| Περιγραφή: | Background: While cardiovascular diseases is highly prevalent and an important cause of mortality in autistic adults, knowledge on their increased cardiovascular risk is limited. Hence, this study aimed to investigate psychological, behavioral, and physical factors associated with metabolic syndrome (MetS) in adults with autistic traits. Methods: In total, 17,705 adults from the Lifelines Cohort were included and categorized using Autism Spectrum Quotient-10 sum-scores. The quartiles with highest (HQ-traits-group females: n = 2,635; males: n = 1803) and lowest levels of autistic traits (LQ-traits-group, n = idem) were analyzed. Using multivariable logistic regression, the associations between MetS and (self-reported and interviewed) psychological, behavioral, and physically measured factors in these stratified groups were investigated. Results: Among females, MetS was more common in the HQ-traits-group than in the LQ-traits-group (10.0% versus 7.5%, p < 0.01), while this was not the case among males (HQ-traits-group 13.8% versus LQ-traits-group 13.1%, p = 0.52). In both the female and male HQ-traits-group, the presence of MetS was associated with poorer self-reported health, less daily physical activity, and altered leukocyte counts. Conclusion: These findings underline the relevance of adequate cardiovascular prevention in adults with higher levels of autistic traits. Future research could gain more insight into the relationship between cardiovascular risk and autistic traits in females, and into tailored cardiovascular prevention. |
| Τύπος εγγράφου: | article in journal/newspaper |
| Περιγραφή αρχείου: | application/pdf |
| Γλώσσα: | English |
| ISSN: | 1664-0640 |
| Relation: | info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/11245.1/b71043fd-d8bb-45b5-9be4-94e6d44c5046; info:eu-repo/semantics/altIdentifier/pissn/1664-0640 |
| DOI: | 10.3389/fpsyt.2023.1303840 |
| Διαθεσιμότητα: | https://dare.uva.nl/personal/pure/en/publications/metabolic-syndrome-in-adults-with-autistic-traits-associated-psychological-behavioral-and-biological-factors-in-females-and-males--a-pharmlines-initiative(b71043fd-d8bb-45b5-9be4-94e6d44c5046).html https://doi.org/10.3389/fpsyt.2023.1303840 https://hdl.handle.net/11245.1/b71043fd-d8bb-45b5-9be4-94e6d44c5046 https://pure.uva.nl/ws/files/186238105/fpsyt-14-1303840.pdf https://www.scopus.com/pages/publications/85181191856 |
| Rights: | info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by/4.0/ |
| Αριθμός Καταχώρησης: | edsbas.A0758649 |
| Βάση Δεδομένων: | BASE |
| ISSN: | 16640640 |
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| DOI: | 10.3389/fpsyt.2023.1303840 |