Academic Journal
Complete genome sequence of Porphyromonas gingivalis strain KCOM 3131 isolated from subgingival dental plaque of a periodontitis patient
| Τίτλος: | Complete genome sequence of Porphyromonas gingivalis strain KCOM 3131 isolated from subgingival dental plaque of a periodontitis patient |
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| Συγγραφείς: | Park, SN, Lim, YK, Ji, S, Kook, JK |
| Συνεισφορές: | 110562, Ji, S |
| Έτος έκδοσης: | 2026 |
| Θεματικοί όροι: | complete genome, periodontitis, Porphyromonas gingivalis, virulence factors |
| Περιγραφή: | We present the complete genome sequence of Porphyromonas gingivalis strain KCOM 3131 (clinical isolate JS238), isolated from the subgingival plaque of a patient with chronic periodontitis. The genome consists of a single circular chromosome (2,359,159 bp; 48.2% G + C content), containing 2,098 genes, including 1,922 protein-coding sequences, 12 rRNA genes, 53 tRNA genes, and 3 CRISPR arrays. Comparative genomic analysis confirmed its taxonomic identity, showing 99.52% 16S rRNA gene similarity, 98.39% OrthoANI, and 87.3% digital DNA-DNA hybridization with the type strain ATCC 33277T. The genome harbors multiple virulence determinants, such as fimbriae, gingipains, hemagglutinins, heme acquisition systems, capsular polysaccharide biosynthesis genes, and type IX secretion system components. This genomic resource will facilitate comparative analyses of P. gingivalis clinical isolates and provide valuable insights into the pathogenic mechanisms underlying chronic periodontitis. |
| Τύπος εγγράφου: | article in journal/newspaper |
| Γλώσσα: | English |
| Relation: | J004402413; https://repository.ajou.ac.kr/handle/201003/38099 |
| DOI: | 10.7845/kjm.2026.5079 |
| Διαθεσιμότητα: | https://repository.ajou.ac.kr/handle/201003/38099 https://doi.org/10.7845/kjm.2026.5079 |
| Αριθμός Καταχώρησης: | edsbas.9FC66C46 |
| Βάση Δεδομένων: | BASE |
| DOI: | 10.7845/kjm.2026.5079 |
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