Academic Journal
Monitoring mouse brain perfusion with hybrid magnetic resonance optoacoustic tomography
| Τίτλος: | Monitoring mouse brain perfusion with hybrid magnetic resonance optoacoustic tomography |
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| Συγγραφείς: | Ren, Wuwei, Deán-Ben, Xosé Luís, Skachokova, Zhiva, Augath, Mark-Aurel, Ni, Ruiqing, Chen, Zhenyue, Razansky, Daniel |
| Πηγή: | Ren, W., Deán-Ben, X. L., Skachokova, Z., Augath, M.-A., Ni, R., Chen, Z., & Razansky, D. (2023). Monitoring mouse brain perfusion with hybrid magnetic resonance optoacoustic tomography. Biomedical Optics Express, 14, 1192–1204. https://doi.org/10.1364/BOE.482205 |
| Στοιχεία εκδότη: | Optical Society of America |
| Έτος έκδοσης: | 2023 |
| Συλλογή: | University of Zurich (UZH): ZORA (Zurich Open Repository and Archive |
| Θεματικοί όροι: | 170 Ethics, 610 Medicine & health |
| Περιγραφή: | Progress in brain research critically depends on the development of next-generation multi-modal imaging tools capable of capturing transient functional events and multiplexed contrasts noninvasively and concurrently, thus enabling a holistic view of dynamic events in vivo. Here we report on a hybrid magnetic resonance and optoacoustic tomography (MROT) system for murine brain imaging, which incorporates an MR-compatible spherical matrix array transducer and fiber-based light illumination into a 9.4 T small animal scanner. An optimized radiofrequency coil has further been devised for whole-brain interrogation. System's utility is showcased by acquiring complementary angiographic and soft tissue anatomical contrast along with simultaneous dual-modality visualization of contrast agent dynamics in vivo. |
| Τύπος εγγράφου: | article in journal/newspaper |
| Περιγραφή αρχείου: | application/pdf |
| Γλώσσα: | English |
| ISSN: | 2156-7085 |
| Relation: | info:pmid/36950237; urn:issn:2156-7085 |
| DOI: | 10.1364/BOE.482205 |
| Διαθεσιμότητα: | https://www.zora.uzh.ch/handle/20.500.14742/208671 https://hdl.handle.net/20.500.14742/208671 https://doi.org/10.1364/BOE.482205 |
| Rights: | info:eu-repo/semantics/openAccess ; Creative Commons: Attribution 4.0 International (CC BY 4.0) ; http://creativecommons.org/licenses/by/4.0/ |
| Αριθμός Καταχώρησης: | edsbas.955FFF77 |
| Βάση Δεδομένων: | BASE |
| ISSN: | 21567085 |
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| DOI: | 10.1364/BOE.482205 |