Academic Journal
Analysis of rheumatoid factor according to various hepatitis B virus infectious statuses
| Τίτλος: | Analysis of rheumatoid factor according to various hepatitis B virus infectious statuses |
|---|---|
| Συνεισφορές: | S T Choi, H W Lee, J S Song, S K Lee, Y B Park, Park, Yong Beom, Lee, Soo Kon |
| Έτος έκδοσης: | 2014 |
| Θεματικοί όροι: | Adult, Age Factors, DNA, Viral/blood, Female, Hepatitis B*/epidemiology, Hepatitis B*/immunology, Hepatitis B*/physiopathology, Hepatitis B Antibodies/blood, Hepatitis B Surface Antigens/blood, Hepatitis B virus*/genetics, Hepatitis B virus*/immunology, Humans, Male, Middle Aged, Patient Acuity, Republic of Korea/epidemiology, Rheumatoid Factor*/analysis, Rheumatoid Factor*/blood, Sex Factors, Statistics as Topic, Viral Load |
| Περιγραφή: | OBJECTIVES: Rheumatoid factor (RF) can be seen in hepatitis B virus (HBV) infection. We investigated RF positive rates according to various HBV infectious statuses and vaccination, and the relationship between RF titers and serum HBV DNA levels. METHODS: We examined 13,670 individuals who visited the Severance Hospital in Seoul, Korea, for a routine health check-up, and obtained serum samples from all individuals. RESULTS: RF was positive in 3.5% of all subjects, and HBsAg was positive in 4.3%. HBsAg was positive in 21.7% of all RF positive subjects. RF was positive in 17.5% of the HBsAg positive group, while it was positive in 2.9% of the HBsAg negative group (p<0.001). The RF positive rate was increased in positive HBsAg, female sex, and older age. The RF positive rate was lower in those who had anti-HBs after HBV vaccination than in HBsAg positive subjects (2.7% vs. 17.5%, p<0.001). Among the RF positive patients, the RF titer in HBsAg positive patients were higher than that in HBsAg negative patients (159.7±217.1IU/mL vs. 83.0±179.2 IU/mL, p=0.001). The load of HBV DNA may be closely correlated with RF titer in patients with chronic hepatitis B (r=0.508, p=0.005). CONCLUSIONS: Persistent HBV infection is an important cause for the positive RF in HBV endemic areas. Hepatitis B viral load is associated with RF titer. HBV vaccination may reduce the risk of RF formation. ; open |
| Τύπος εγγράφου: | article in journal/newspaper |
| Περιγραφή αρχείου: | 168~173 |
| Γλώσσα: | unknown |
| Relation: | CLINICAL AND EXPERIMENTAL RHEUMATOLOGY; J00555; https://ir.ymlib.yonsei.ac.kr/handle/22282913/138816; http://www.clinexprheumatol.org/abstract.asp?a=7153; T201405670; 54939 |
| Διαθεσιμότητα: | https://ir.ymlib.yonsei.ac.kr/handle/22282913/138816 http://www.clinexprheumatol.org/abstract.asp?a=7153 |
| Rights: | CC BY-NC-ND 2.0 KR ; https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ ; free |
| Αριθμός Καταχώρησης: | edsbas.84EABADB |
| Βάση Δεδομένων: | BASE |
| Η περιγραφή δεν είναι διαθέσιμη |