Investigation of whole cell meningococcal glycan interactions using high throughput glycobiology techniques: Glycan array and surface plasmon resonance

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Investigation of whole cell meningococcal glycan interactions using high throughput glycobiology techniques: Glycan array and surface plasmon resonance
Συγγραφείς: Mubaiwa, TD, Hartley-Tassell, LE, Semchenko, EA, Day, CJ, Jennings, MP, Seib, KL
Στοιχεία εκδότη: Springer
Έτος έκδοσης: 2019
Συλλογή: Griffith University: Griffith Research Online
Θεματικοί όροι: Glycobiology, Biochemistry and Cell Biology, Biological Sciences, Other chemical sciences, Medicinal and biomolecular chemistry, Glycan arrays, Surface plasmon resonance (SPR)
Περιγραφή: A growing body of evidence suggests that glycans are important for meningococcal host-pathogen interactions and virulence. The development of glycobiology techniques such as glycan array analysis and surface plasmon resonance (SPR) has increased awareness of the importance of glycans in biological processes and has increased the interest of their study. While these techniques are more routinely used with purified proteins, there is growing interest in their applicability to cell-based studies, to better emulate host-pathogen interactions in vivo. Here we describe the use of glycan array analysis and SPR for the investigation of glycan binding by Neisseria meningitidis cells. Used together, these methods can help identify and characterize N. meningitidis glycointeractions. ; Full Text
Τύπος εγγράφου: book part
Γλώσσα: English
Relation: Neisseria meningitidis: Methods and Protocols; http://purl.org/au-research/grants/nhmrc/1099278; http://purl.org/au-research/grants/nhmrc/1045235; NHMRC; https://hdl.handle.net/10072/384118
DOI: 10.1007/978-1-4939-9202-7_8
Διαθεσιμότητα: https://hdl.handle.net/10072/384118
https://doi.org/10.1007/978-1-4939-9202-7_8
Rights: © 2019 Springer. This is an electronic version of an article published in Methods in Molecular Biology, Vol. 1969:113-121, January 2019. Methods in Molecular Biology (Neisseria meningitidis) is available online at: http://link.springer.com/ with the open URL of your article. ; open access
Αριθμός Καταχώρησης: edsbas.5BA29650
Βάση Δεδομένων: BASE
Περιγραφή
DOI:10.1007/978-1-4939-9202-7_8