Academic Journal
Data from: A low-threshold potassium current enhances sparseness and reliability in a model of avian auditory cortex
| Τίτλος: | Data from: A low-threshold potassium current enhances sparseness and reliability in a model of avian auditory cortex |
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| Συγγραφείς: | Bjoring, Margot C., Meliza, C. Daniel |
| Έτος έκδοσης: | 2019 |
| Συλλογή: | Dryad Digital Repository (Duke University) |
| Θεματικοί όροι: | auditory processing, intrinsic dynamics, decoding models, selectivity, tolerance, object recognition |
| Περιγραφή: | Birdsong is a complex vocal communication signal, and like humans, birds need to discriminate between similar sequences of sound with different meanings. The caudal mesopallium (CM) is a cortical-level auditory area implicated in song discrimination. CM neurons respond sparsely to conspecific song and are tolerant of production variability. Intracellular recordings in CM have identified a diversity of intrinsic membrane dynamics, which could contribute to the emergence of these higher-order functional properties. We investigated this hypothesis using a novel linear-dynamical cascade model that incorporated detailed biophysical dynamics to simulate auditory responses to birdsong. Neuron models that included a low-threshold potassium current present in a subset of CM neurons showed increased selectivity and coding efficiency relative to models without this current. These results demonstrate the impact of intrinsic dynamics on sensory coding and the importance of including the biophysical characteristics of neural populations in simulation studies. |
| Τύπος εγγράφου: | article in journal/newspaper |
| Γλώσσα: | unknown |
| Relation: | Bjoring MC, Meliza CD (2019) A low-threshold potassium current enhances sparseness and reliability in a model of avian auditory cortex. PLOS Computational Biology 15(1): e1006723.; http://hdl.handle.net/10255/dryad.203534 |
| DOI: | 10.5061/dryad.js11601 |
| Διαθεσιμότητα: | http://hdl.handle.net/10255/dryad.203534 https://doi.org/10.5061/dryad.js11601 |
| Αριθμός Καταχώρησης: | edsbas.34D34D48 |
| Βάση Δεδομένων: | BASE |
| DOI: | 10.5061/dryad.js11601 |
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