Academic Journal
Sleep apnea phenotypes based on multi-night assessment of sleep perception
| Τίτλος: | Sleep apnea phenotypes based on multi-night assessment of sleep perception |
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| Συγγραφείς: | Kuhn, Jasmin, Schiphorst, Laura R.B., Wulterkens, Bernice M., Asin, Jerryll, Overeem, Sebastiaan, van Gilst, Merel M., Fonseca, Pedro |
| Πηγή: | Kuhn, J, Schiphorst, L R B, Wulterkens, B M, Asin, J, Overeem, S, van Gilst, M M & Fonseca, P 2026, 'Sleep apnea phenotypes based on multi-night assessment of sleep perception', Behavioral Sleep Medicine, vol. 24, no. 4, pp. 430-442. https://doi.org/10.1080/15402002.2026.2630936 |
| Έτος έκδοσης: | 2026 |
| Θεματικοί όροι: | Humans, Female, Male, Phenotype, Middle Aged, Polysomnography/methods, Adult, Sleep Apnea, Obstructive/physiopathology, Sleep Duration, Sleep/physiology, Photoplethysmography/methods, Perception/physiology, Aged, Sleep Quality, Quality of Life |
| Περιγραφή: | OBJECTIVES: Sleep time discrepancy is associated with a lower quality of life and is common in individuals with obstructive sleep apnea (OSA) during polysomnography (PSG), but little is known about multi-night sleep perception patterns in the habitual sleeping environment. We conducted multi-night measurements using a validated wrist-worn photoplethysmography sensor and a digital sleep diary, to identify OSA phenotypes based on sleep perception patterns. METHOD: Sleep time discrepancy was evaluated using the misperception index (MI). K-means clustering was used to identify sleep perception patterns using two features: the median and median absolute deviation of a participant's multi-night MI values. Clusters were compared across clinical and demographic parameters. RESULTS: Based on 1485 recording nights of 120 individuals with OSA we identified four sleep perception clusters: accurate estimation ( n = 64), underestimation ( n = 33, with more insomnia symptoms and lower self-reported sleep quality), severe underestimation ( n = 6, similar to underestimation, with high pre-sleep cognitive arousal) and variable overestimation ( n = 17, older age, with higher apnea-hypopnea index and more disrupted sleep). CONCLUSIONS: Distinct OSA phenotypes can be identified based on multi-night sleep perception patterns, and they present with diverging clinical characteristics. This highlights the heterogeneity of the OSA population and may facilitate the development of more personalized treatment approaches. |
| Τύπος εγγράφου: | article in journal/newspaper |
| Περιγραφή αρχείου: | application/pdf |
| Γλώσσα: | English |
| ISSN: | 1540-2002 1540-2010 |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/41689504; info:eu-repo/semantics/altIdentifier/pissn/1540-2002; info:eu-repo/semantics/altIdentifier/eissn/1540-2010 |
| DOI: | 10.1080/15402002.2026.2630936 |
| Διαθεσιμότητα: | https://research.tue.nl/en/publications/7157ec5a-a9ce-47e3-8f3b-3301bc392017 https://doi.org/10.1080/15402002.2026.2630936 https://pure.tue.nl/ws/files/396042495/Sleep_apnea_phenotypes_based_on_multi-night_assessment_of_sleep_perception.pdf https://www.scopus.com/pages/publications/105030191069 |
| Rights: | info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by/4.0/ |
| Αριθμός Καταχώρησης: | edsbas.2078D6C1 |
| Βάση Δεδομένων: | BASE |
| ISSN: | 15402002 15402010 |
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| DOI: | 10.1080/15402002.2026.2630936 |