Academic Journal
Genomic epidemiology of Vibrio cholerae during a mass vaccination campaign of displaced communities in Bangladesh
| Τίτλος: | Genomic epidemiology of Vibrio cholerae during a mass vaccination campaign of displaced communities in Bangladesh |
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| Συγγραφείς: | Taylor-Brown, A, Afrad, MH, Khan, AI, Lassalle, F, Islam, MT, Tanvir, NA, Thomson, NR, Qadri, F |
| Στοιχεία εκδότη: | Nature Publishing |
| Έτος έκδοσης: | 2023 |
| Συλλογή: | Griffith University: Griffith Research Online |
| Περιγραφή: | Ongoing diarrheal disease surveillance throughout Bangladesh over the last decade has revealed seasonal localised cholera outbreaks in Cox’s Bazar, where both Bangladeshi Nationals and Forcibly Displaced Myanmar Nationals (FDMNs) reside in densely populated settlements. FDMNs were recently targeted for the largest cholera vaccination campaign in decades. We aimed to infer the epidemic risk of circulating Vibrio cholerae strains by determining if isolates linked to the ongoing global cholera pandemic (“7PET” lineage) were responsible for outbreaks in Cox’s Bazar. We found two sublineages of 7PET in this setting during the study period; one with global distribution, and a second lineage restricted to Asia and the Middle East. These subclades were associated with different disease patterns that could be partially explained by genomic differences. Here we show that as the pandemic V. cholerae lineage circulates in this vulnerable population, without a vaccine intervention, the risk of an epidemic was very high. ; Full Text |
| Τύπος εγγράφου: | article in journal/newspaper |
| Γλώσσα: | English |
| Relation: | Nature Communications; Taylor-Brown, A; Afrad, MH; Khan, AI; Lassalle, F; Islam, MT; Tanvir, NA; Thomson, NR; Qadri, F, Genomic epidemiology of Vibrio cholerae during a mass vaccination campaign of displaced communities in Bangladesh, Nature Communications, 2023, 14 (1), pp. 3773; https://hdl.handle.net/10072/432745 |
| DOI: | 10.1038/s41467-023-39415-3 |
| Διαθεσιμότητα: | https://hdl.handle.net/10072/432745 https://doi.org/10.1038/s41467-023-39415-3 |
| Rights: | https://creativecommons.org/licenses/by/4.0/ ; © The Author(s) 2023. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. ; open access |
| Αριθμός Καταχώρησης: | edsbas.13573C6F |
| Βάση Δεδομένων: | BASE |
| DOI: | 10.1038/s41467-023-39415-3 |
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