Academic Journal

Features of the choice and the use of antiepileptic drugs as analgesics in elderly

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Features of the choice and the use of antiepileptic drugs as analgesics in elderly
Συγγραφείς: Ushkalova E.A., Zyryanov S.K., Butranova O.I.
Πηγή: Advances in gerontology = Uspekhi gerontologii. 35(5)
Στοιχεία εκδότη: 2023.
Έτος έκδοσης: 2023
Θεματικοί όροι: Analgesics, Levetiracetam, анальгетики, elderly, хроническая боль, Topiramate, analgesics, противоэпилептические средства, Humans, Anticonvulsants, пациенты пожилого возраста, Chronic Pain, antiepileptics, chronic pain, Aged
Περιγραφή: High prevalence of chronic pain in elderly results in active search of new approaches for the effective and safe management of this category of patients. Antiepileptic drugs may provide analgesic affect in different types of chronic pain (mainly, in neuropathic pain). Variety of antiepileptics used as analgesics have variable efficacy and safety profile in elderly. «Old» antiepileptics (phenobarbital, clonazepam, ethosuximide, carbamazepine, phenytoin, valproate, etc.) and «new» (gabapentin, pregabalin, oxcarbazepine, lamotrigine, levetiracetam, topiramate, zonisamide, tiagabine) are considered in this review with insights on pharmacokinetic features of these drugs in elderly, profile of side effects, parameters of analgesic efficacy.
Τύπος εγγράφου: Article
Γλώσσα: English
ISSN: 1561-9125
Σύνδεσμος πρόσβασης: https://pubmed.ncbi.nlm.nih.gov/36617332
Αριθμός Καταχώρησης: edsair.pmid.dedup....6ab8e8a2b4d6be89417d6ec72a0c9b3d
Βάση Δεδομένων: OpenAIRE