Bibliographic Details
| Title: |
Features of the choice and the use of antiepileptic drugs as analgesics in elderly |
| Authors: |
Ushkalova E.A., Zyryanov S.K., Butranova O.I. |
| Source: |
Advances in gerontology = Uspekhi gerontologii. 35(5) |
| Publisher Information: |
2023. |
| Publication Year: |
2023 |
| Subject Terms: |
Analgesics, Levetiracetam, анальгетики, elderly, хроническая боль, Topiramate, analgesics, противоэпилептические средства, Humans, Anticonvulsants, пациенты пожилого возраста, Chronic Pain, antiepileptics, chronic pain, Aged |
| Description: |
High prevalence of chronic pain in elderly results in active search of new approaches for the effective and safe management of this category of patients. Antiepileptic drugs may provide analgesic affect in different types of chronic pain (mainly, in neuropathic pain). Variety of antiepileptics used as analgesics have variable efficacy and safety profile in elderly. «Old» antiepileptics (phenobarbital, clonazepam, ethosuximide, carbamazepine, phenytoin, valproate, etc.) and «new» (gabapentin, pregabalin, oxcarbazepine, lamotrigine, levetiracetam, topiramate, zonisamide, tiagabine) are considered in this review with insights on pharmacokinetic features of these drugs in elderly, profile of side effects, parameters of analgesic efficacy. |
| Document Type: |
Article |
| Language: |
English |
| ISSN: |
1561-9125 |
| Access URL: |
https://pubmed.ncbi.nlm.nih.gov/36617332 |
| Accession Number: |
edsair.pmid.dedup....6ab8e8a2b4d6be89417d6ec72a0c9b3d |
| Database: |
OpenAIRE |