Academic Journal
Use of sedation‐awakening electroencephalography in dogs with epilepsy
| Title: | Use of sedation‐awakening electroencephalography in dogs with epilepsy |
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| Authors: | Marcin Wrzosek, Aleksandra Banasik, Adriana Czerwik, Agnieszka Olszewska, Marta Płonek, Veronika Stein |
| Source: | J Vet Intern Med Journal of Veterinary Internal Medicine, Vol 38, Iss 5, Pp 2578-2589 (2024) Wrzosek, Marcin; Banasik, Aleksandra; Czerwik, Adriana; Olszewska, Agnieszka; Płonek, Marta; Stein, Veronika (2024). Use of sedation-awakening electroencephalography in dogs with epilepsy. Journal of veterinary internal medicine, 38(5), pp. 2578-2589. Wiley 10.1111/jvim.17153 <http://dx.doi.org/10.1111/jvim.17153> |
| Publisher Information: | Wiley, 2024. |
| Publication Year: | 2024 |
| Subject Terms: | Male, canine epilepsy diagnosis, Veterinary medicine, Conscious Sedation, canine electroencephalography, 0403 veterinary science, 03 medical and health sciences, Dogs, 0302 clinical medicine, SF600-1100, Animals, Hypnotics and Sedatives, Dog Diseases, Prospective Studies, Retrospective Studies, Epilepsy, 630 Agriculture, Imidazoles, Electroencephalography, 04 agricultural and veterinary sciences, Medetomidine, 3. Good health, sedation, paroxysmal, ambulatory EEG, epilepsy, Female, SMALL ANIMAL |
| Description: | BackgroundElectroencephalography (EEG) recording protocols have been standardized for humans. Although the utilization of techniques in veterinary medicine is increasing, a standard protocol has not yet been established.HypothesisAssessment of a sedation‐awakening EEG protocol in dogs.AnimalsElectroencephalography examination was performed in a research colony of 6 nonepileptic dogs (control [C]) and 12 dogs with epilepsy admitted to the clinic because of the epileptic seizures.MethodsIt was a prospective study with retrospective control. Dogs with epilepsy were divided into 2 equal groups, wherein EEG acquisition was performed using a “sedation” protocol (IE‐S, n = 6) and a “sedation‐awakening” protocol (IE‐SA, n = 6). All animals were sedated using medetomidine. In IE‐SA group, sedation was reversed 5 minutes after commencing the EEG recording by injecting atipamezole IM. Type of background activity (BGA) and presence of EEG‐defined epileptiform discharges (EDs) were evaluated blindly. Statistical significance was set at P > 0.05.ResultsEpileptiform discharges were found in 1 of 6 of the dogs in group C, 4 of 6 of the dogs in IE‐S group, and 5 of 6 of the dogs in IE‐SA group. A significantly greater number of EDs (spikes, P = .0109; polyspikes, P = .0109; sharp waves, P = .01) were detected in Phase 2 in animals subjected to the “sedation‐awakening” protocol, whereas there was no statistically significant greater number of discharges in sedated animals.Conclusions and Clinical ImportanceA “sedation‐awakening” EEG protocol could be of value for ambulatory use if repeated EEG recordings and monitoring of epilepsy in dogs is needed. |
| Document Type: | Article Other literature type |
| File Description: | application/pdf |
| Language: | English |
| ISSN: | 1939-1676 0891-6640 |
| DOI: | 10.1111/jvim.17153 |
| DOI: | 10.48350/199654 |
| Access URL: | https://pubmed.ncbi.nlm.nih.gov/39133769 https://doaj.org/article/cf8963ef10924e7a90ce9c0c5143fa94 https://boris.unibe.ch/199654/ |
| Rights: | CC BY |
| Accession Number: | edsair.doi.dedup.....f56d359bce14b6b7f044b2065a9e58ef |
| Database: | OpenAIRE |
| ISSN: | 19391676 08916640 |
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| DOI: | 10.1111/jvim.17153 |