Academic Journal

Multiple primary cancer in Leser — Trelat syndrome (description of a clinical case)

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Multiple primary cancer in Leser — Trelat syndrome (description of a clinical case)
Συγγραφείς: Bondar, V. G., Kayryak, O. V., Vasiliev, V. V., Gubergrits, N. B., Mozhyna, T. L.
Πηγή: Modern Gastroenterology; № 5 (2020); 65—70
Современная гастроэнтерология; № 5 (2020); 65—70
Сучасна гастроентерологія; № 5 (2020); 65—70
Στοιχεία εκδότη: Publishing Company VIT-A-POL, 2020.
Έτος έκδοσης: 2020
Θεματικοί όροι: синдром Лезера — Трела, паранеоплазия, себорейная кератома, первично‑множественный рак, паранеоплазії, себорейна кератома, первинно‑множинний рак, Leser — Trelat syndrome, paraneoplasia, seborrheic keratoma, multiple primary cancer, 3. Good health
Περιγραφή: The article provides information about one of the typical paraneoplastic syndromes — Leser — Trelat syndrome, a condition that develops jointly and sometimes precedes the appearance of a malignant visceral tumor. Brief clinical characteristics of Leser — Trelat syndrome are presented. Its predominant development in elderly and senile patients has been outlined, as well as its predominant association with malignant neoplasms of the gastrointestinal tract (47.7 %), lungs, mammary glands, prostate, kidneys, liver, T‑cell lymphomas (fungal mycosis, Sesari syndrome). Possible atypical relationships of Leser — Trelat syndrome with basalioma of the lower eyelid, skin melanoma are disclosed. Cases of fast (several months) and slow (years) formation of this paraneoplastic syndrome with a typical widespread nature of the lesion and a rare focal localization of keratomas are described. A clinical case with typical manifestations of dermatological paraneoplastic syndrome in the form of Leser — Trelat syndrome in a patient with multiple primary metachronous cancer is presented: right breast cancer (T2N0M0; ER‑, PR‑, HER2neu‑; 2017), right kidney cancer (T1N0M0; 24.02.2020), cancer of the rectum and sigmoid colon (T4N0M0; 22.07.2020). Pathological signs of malignant transformation of female genitals, peripheral lymph nodes were not found. Combined treatment (surgical intervention: resection of right kidney, combined resection of sigmoid colon, extirpation of uterus with appendages, polypectomy of colon in combination with a course of chemotherapy in a neoadjuvant mode) facilitated the resolution of seborrheic adenomas, which confirmed the paraneoplastic nature of Leser — Trelat syndrome.
Τύπος εγγράφου: Article
Other literature type
Περιγραφή αρχείου: application/pdf
ISSN: 2521-649X
1727-5725
DOI: 10.30978/mg-2020-5-65
Σύνδεσμος πρόσβασης: http://sgastro.com.ua/article/view/MG-2020-5-65
Αριθμός Καταχώρησης: edsair.doi.dedup.....e49694b64d2907470a8cf7dc2bc0e4d4
Βάση Δεδομένων: OpenAIRE
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  Data: Multiple primary cancer in Leser — Trelat syndrome (description of a clinical case)
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  Data: <searchLink fieldCode="AR" term="%22Bondar%2C+V%2E+G%2E%22">Bondar, V. G.</searchLink><br /><searchLink fieldCode="AR" term="%22Kayryak%2C+O%2E+V%2E%22">Kayryak, O. V.</searchLink><br /><searchLink fieldCode="AR" term="%22Vasiliev%2C+V%2E+V%2E%22">Vasiliev, V. V.</searchLink><br /><searchLink fieldCode="AR" term="%22Gubergrits%2C+N%2E+B%2E%22">Gubergrits, N. B.</searchLink><br /><searchLink fieldCode="AR" term="%22Mozhyna%2C+T%2E+L%2E%22">Mozhyna, T. L.</searchLink>
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  Data: Modern Gastroenterology; № 5 (2020); 65—70<br />Современная гастроэнтерология; № 5 (2020); 65—70<br />Сучасна гастроентерологія; № 5 (2020); 65—70
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  Data: 2020
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  Data: <searchLink fieldCode="DE" term="%22синдром+Лезера+—+Трела%22">синдром Лезера — Трела</searchLink><br /><searchLink fieldCode="DE" term="%22паранеоплазия%22">паранеоплазия</searchLink><br /><searchLink fieldCode="DE" term="%22себорейная+кератома%22">себорейная кератома</searchLink><br /><searchLink fieldCode="DE" term="%22первично‑множественный+рак%22">первично‑множественный рак</searchLink><br /><searchLink fieldCode="DE" term="%22паранеоплазії%22">паранеоплазії</searchLink><br /><searchLink fieldCode="DE" term="%22себорейна+кератома%22">себорейна кератома</searchLink><br /><searchLink fieldCode="DE" term="%22первинно‑множинний+рак%22">первинно‑множинний рак</searchLink><br /><searchLink fieldCode="DE" term="%22Leser+—+Trelat+syndrome%22">Leser — Trelat syndrome</searchLink><br /><searchLink fieldCode="DE" term="%22paraneoplasia%22">paraneoplasia</searchLink><br /><searchLink fieldCode="DE" term="%22seborrheic+keratoma%22">seborrheic keratoma</searchLink><br /><searchLink fieldCode="DE" term="%22multiple+primary+cancer%22">multiple primary cancer</searchLink><br /><searchLink fieldCode="DE" term="%223%2E+Good+health%22">3. Good health</searchLink>
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  Data: The article provides information about one of the typical paraneoplastic syndromes — Leser — Trelat syndrome, a condition that develops jointly and sometimes precedes the appearance of a malignant visceral tumor. Brief clinical characteristics of Leser — Trelat syndrome are presented. Its predominant development in elderly and senile patients has been outlined, as well as its predominant association with malignant neoplasms of the gastrointestinal tract (47.7 %), lungs, mammary glands, prostate, kidneys, liver, T‑cell lymphomas (fungal mycosis, Sesari syndrome). Possible atypical relationships of Leser — Trelat syndrome with basalioma of the lower eyelid, skin melanoma are disclosed. Cases of fast (several months) and slow (years) formation of this paraneoplastic syndrome with a typical widespread nature of the lesion and a rare focal localization of keratomas are described. A clinical case with typical manifestations of dermatological paraneoplastic syndrome in the form of Leser — Trelat syndrome in a patient with multiple primary metachronous cancer is presented: right breast cancer (T2N0M0; ER‑, PR‑, HER2neu‑; 2017), right kidney cancer (T1N0M0; 24.02.2020), cancer of the rectum and sigmoid colon (T4N0M0; 22.07.2020). Pathological signs of malignant transformation of female genitals, peripheral lymph nodes were not found. Combined treatment (surgical intervention: resection of right kidney, combined resection of sigmoid colon, extirpation of uterus with appendages, polypectomy of colon in combination with a course of chemotherapy in a neoadjuvant mode) facilitated the resolution of seborrheic adenomas, which confirmed the paraneoplastic nature of Leser — Trelat syndrome.
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  Data: 10.30978/mg-2020-5-65
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  Data: <link linkTarget="URL" linkTerm="http://sgastro.com.ua/article/view/MG-2020-5-65" linkWindow="_blank">http://sgastro.com.ua/article/view/MG-2020-5-65</link>
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      – SubjectFull: синдром Лезера — Трела
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      – SubjectFull: паранеоплазия
        Type: general
      – SubjectFull: себорейная кератома
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      – SubjectFull: первично‑множественный рак
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