Academic Journal
Multiple primary cancer in Leser — Trelat syndrome (description of a clinical case)
| Τίτλος: | Multiple primary cancer in Leser — Trelat syndrome (description of a clinical case) |
|---|---|
| Συγγραφείς: | Bondar, V. G., Kayryak, O. V., Vasiliev, V. V., Gubergrits, N. B., Mozhyna, T. L. |
| Πηγή: | Modern Gastroenterology; № 5 (2020); 65—70 Современная гастроэнтерология; № 5 (2020); 65—70 Сучасна гастроентерологія; № 5 (2020); 65—70 |
| Στοιχεία εκδότη: | Publishing Company VIT-A-POL, 2020. |
| Έτος έκδοσης: | 2020 |
| Θεματικοί όροι: | синдром Лезера — Трела, паранеоплазия, себорейная кератома, первично‑множественный рак, паранеоплазії, себорейна кератома, первинно‑множинний рак, Leser — Trelat syndrome, paraneoplasia, seborrheic keratoma, multiple primary cancer, 3. Good health |
| Περιγραφή: | The article provides information about one of the typical paraneoplastic syndromes — Leser — Trelat syndrome, a condition that develops jointly and sometimes precedes the appearance of a malignant visceral tumor. Brief clinical characteristics of Leser — Trelat syndrome are presented. Its predominant development in elderly and senile patients has been outlined, as well as its predominant association with malignant neoplasms of the gastrointestinal tract (47.7 %), lungs, mammary glands, prostate, kidneys, liver, T‑cell lymphomas (fungal mycosis, Sesari syndrome). Possible atypical relationships of Leser — Trelat syndrome with basalioma of the lower eyelid, skin melanoma are disclosed. Cases of fast (several months) and slow (years) formation of this paraneoplastic syndrome with a typical widespread nature of the lesion and a rare focal localization of keratomas are described. A clinical case with typical manifestations of dermatological paraneoplastic syndrome in the form of Leser — Trelat syndrome in a patient with multiple primary metachronous cancer is presented: right breast cancer (T2N0M0; ER‑, PR‑, HER2neu‑; 2017), right kidney cancer (T1N0M0; 24.02.2020), cancer of the rectum and sigmoid colon (T4N0M0; 22.07.2020). Pathological signs of malignant transformation of female genitals, peripheral lymph nodes were not found. Combined treatment (surgical intervention: resection of right kidney, combined resection of sigmoid colon, extirpation of uterus with appendages, polypectomy of colon in combination with a course of chemotherapy in a neoadjuvant mode) facilitated the resolution of seborrheic adenomas, which confirmed the paraneoplastic nature of Leser — Trelat syndrome. |
| Τύπος εγγράφου: | Article Other literature type |
| Περιγραφή αρχείου: | application/pdf |
| ISSN: | 2521-649X 1727-5725 |
| DOI: | 10.30978/mg-2020-5-65 |
| Σύνδεσμος πρόσβασης: | http://sgastro.com.ua/article/view/MG-2020-5-65 |
| Αριθμός Καταχώρησης: | edsair.doi.dedup.....e49694b64d2907470a8cf7dc2bc0e4d4 |
| Βάση Δεδομένων: | OpenAIRE |
| FullText | Text: Availability: 0 |
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| Header | DbId: edsair DbLabel: OpenAIRE An: edsair.doi.dedup.....e49694b64d2907470a8cf7dc2bc0e4d4 RelevancyScore: 887 AccessLevel: 3 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 887.259948730469 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Multiple primary cancer in Leser — Trelat syndrome (description of a clinical case) – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Bondar%2C+V%2E+G%2E%22">Bondar, V. G.</searchLink><br /><searchLink fieldCode="AR" term="%22Kayryak%2C+O%2E+V%2E%22">Kayryak, O. V.</searchLink><br /><searchLink fieldCode="AR" term="%22Vasiliev%2C+V%2E+V%2E%22">Vasiliev, V. V.</searchLink><br /><searchLink fieldCode="AR" term="%22Gubergrits%2C+N%2E+B%2E%22">Gubergrits, N. B.</searchLink><br /><searchLink fieldCode="AR" term="%22Mozhyna%2C+T%2E+L%2E%22">Mozhyna, T. L.</searchLink> – Name: TitleSource Label: Source Group: Src Data: Modern Gastroenterology; № 5 (2020); 65—70<br />Современная гастроэнтерология; № 5 (2020); 65—70<br />Сучасна гастроентерологія; № 5 (2020); 65—70 – Name: Publisher Label: Publisher Information Group: PubInfo Data: Publishing Company VIT-A-POL, 2020. – Name: DatePubCY Label: Publication Year Group: Date Data: 2020 – Name: Subject Label: Subject Terms Group: Su Data: <searchLink fieldCode="DE" term="%22синдром+Лезера+—+Трела%22">синдром Лезера — Трела</searchLink><br /><searchLink fieldCode="DE" term="%22паранеоплазия%22">паранеоплазия</searchLink><br /><searchLink fieldCode="DE" term="%22себорейная+кератома%22">себорейная кератома</searchLink><br /><searchLink fieldCode="DE" term="%22первично‑множественный+рак%22">первично‑множественный рак</searchLink><br /><searchLink fieldCode="DE" term="%22паранеоплазії%22">паранеоплазії</searchLink><br /><searchLink fieldCode="DE" term="%22себорейна+кератома%22">себорейна кератома</searchLink><br /><searchLink fieldCode="DE" term="%22первинно‑множинний+рак%22">первинно‑множинний рак</searchLink><br /><searchLink fieldCode="DE" term="%22Leser+—+Trelat+syndrome%22">Leser — Trelat syndrome</searchLink><br /><searchLink fieldCode="DE" term="%22paraneoplasia%22">paraneoplasia</searchLink><br /><searchLink fieldCode="DE" term="%22seborrheic+keratoma%22">seborrheic keratoma</searchLink><br /><searchLink fieldCode="DE" term="%22multiple+primary+cancer%22">multiple primary cancer</searchLink><br /><searchLink fieldCode="DE" term="%223%2E+Good+health%22">3. Good health</searchLink> – Name: Abstract Label: Description Group: Ab Data: The article provides information about one of the typical paraneoplastic syndromes — Leser — Trelat syndrome, a condition that develops jointly and sometimes precedes the appearance of a malignant visceral tumor. Brief clinical characteristics of Leser — Trelat syndrome are presented. Its predominant development in elderly and senile patients has been outlined, as well as its predominant association with malignant neoplasms of the gastrointestinal tract (47.7 %), lungs, mammary glands, prostate, kidneys, liver, T‑cell lymphomas (fungal mycosis, Sesari syndrome). Possible atypical relationships of Leser — Trelat syndrome with basalioma of the lower eyelid, skin melanoma are disclosed. Cases of fast (several months) and slow (years) formation of this paraneoplastic syndrome with a typical widespread nature of the lesion and a rare focal localization of keratomas are described. A clinical case with typical manifestations of dermatological paraneoplastic syndrome in the form of Leser — Trelat syndrome in a patient with multiple primary metachronous cancer is presented: right breast cancer (T2N0M0; ER‑, PR‑, HER2neu‑; 2017), right kidney cancer (T1N0M0; 24.02.2020), cancer of the rectum and sigmoid colon (T4N0M0; 22.07.2020). Pathological signs of malignant transformation of female genitals, peripheral lymph nodes were not found. Combined treatment (surgical intervention: resection of right kidney, combined resection of sigmoid colon, extirpation of uterus with appendages, polypectomy of colon in combination with a course of chemotherapy in a neoadjuvant mode) facilitated the resolution of seborrheic adenomas, which confirmed the paraneoplastic nature of Leser — Trelat syndrome. – Name: TypeDocument Label: Document Type Group: TypDoc Data: Article<br />Other literature type – Name: Format Label: File Description Group: SrcInfo Data: application/pdf – Name: ISSN Label: ISSN Group: ISSN Data: 2521-649X<br />1727-5725 – Name: DOI Label: DOI Group: ID Data: 10.30978/mg-2020-5-65 – Name: URL Label: Access URL Group: URL Data: <link linkTarget="URL" linkTerm="http://sgastro.com.ua/article/view/MG-2020-5-65" linkWindow="_blank">http://sgastro.com.ua/article/view/MG-2020-5-65</link> – Name: AN Label: Accession Number Group: ID Data: edsair.doi.dedup.....e49694b64d2907470a8cf7dc2bc0e4d4 |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsair&AN=edsair.doi.dedup.....e49694b64d2907470a8cf7dc2bc0e4d4 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.30978/mg-2020-5-65 Languages: – Text: Undetermined PhysicalDescription: Pagination: PageCount: 6 StartPage: 65 Subjects: – SubjectFull: синдром Лезера — Трела Type: general – SubjectFull: паранеоплазия Type: general – SubjectFull: себорейная кератома Type: general – SubjectFull: первично‑множественный рак Type: general – SubjectFull: паранеоплазії Type: general – SubjectFull: себорейна кератома Type: general – SubjectFull: первинно‑множинний рак Type: general – SubjectFull: Leser — Trelat syndrome Type: general – SubjectFull: paraneoplasia Type: general – SubjectFull: seborrheic keratoma Type: general – SubjectFull: multiple primary cancer Type: general – SubjectFull: 3. Good health Type: general Titles: – TitleFull: Multiple primary cancer in Leser — Trelat syndrome (description of a clinical case) Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Bondar, V. G. – PersonEntity: Name: NameFull: Kayryak, O. V. – PersonEntity: Name: NameFull: Vasiliev, V. V. – PersonEntity: Name: NameFull: Gubergrits, N. B. – PersonEntity: Name: NameFull: Mozhyna, T. L. IsPartOfRelationships: – BibEntity: Dates: – D: 16 M: 11 Type: published Y: 2020 Identifiers: – Type: issn-print Value: 2521649X – Type: issn-print Value: 17275725 – Type: issn-locals Value: edsair Numbering: – Type: volume Value: 0 Titles: – TitleFull: Modern Gastroenterology Type: main |
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