Academic Journal
Patient-centred outcome following endoscopic management of benign central airway obstruction
| Τίτλος: | Patient-centred outcome following endoscopic management of benign central airway obstruction |
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| Συγγραφείς: | Mads Bøgh, Dalia Gustaityté Larsen, Matilde Lonka, Sten Schytte, Ulrik Pedersen, Søren Gade, Padraig O’Leary, Thomas Kjaergaard |
| Πηγή: | Eur Arch Otorhinolaryngol Bøgh, M, Larsen, D G, Lonka, M, Schytte, S, Pedersen, U, Gade, S, O'Leary, P & Kjaergaard, T 2025, 'Patient-centred outcome following endoscopic management of benign central airway obstruction', European Archives of Oto-Rhino-Laryngology, vol. 282, no. 4, pp. 2001-2007. https://doi.org/10.1007/s00405-025-09230-1 |
| Στοιχεία εκδότη: | Springer Science and Business Media LLC, 2025. |
| Έτος έκδοσης: | 2025 |
| Θεματικοί όροι: | Postoperative Complications/epidemiology, Male, Adult, Reoperation, Tracheal Stenosis/surgery, Endoscopy/methods, Laryngology, Young Adult, Postoperative complications, Therapeutic bronchoscopy, Postoperative Complications, Dilatation/methods, Humans, Aged, Retrospective Studies, Aged, 80 and over, Tracheobronchomalacia, Airway Obstruction/surgery, Endoscopy, Middle Aged, Airway Obstruction, Reoperation/statistics & numerical data, Treatment Outcome, Benign, Central airway obstruction, Female, Stents, Patient-relevant outcome |
| Περιγραφή: | Purpose To examine patient-centred outcome following endoscopic treatment of central airway stenosis in terms of days alive and out of hospital (DAOH), need for re-intervention, and complications, with reference to aetiology of disease and applied treatment methodology. Methods Analyses were based on data from consecutive adult patients treated endoscopically for benign central airway obstruction at Aarhus University Hospital from 2012 to 2022, with a minimum follow-up of one year. DAOH was calculated for 30 and 365 days. Complications were graded based on the Clavien-Dindo classification. Univariate and multivariate analyses were performed to identify predictors for DAOH, re-intervention and complications. Results 82 consecutive adult patients underwent endoscopic treatment during the period of inclusion, comprising a total of 175 dilatations, 42 benign tumour resections, and 67 stent insertions. Multiple interventions and short re-intervention intervals was more likely amongst patients reporting significant preoperative dyspnoea or requiring preoperative respiratory support, as well as patients treated with endoscopic insertion of silicone stents. The overall complication rate per procedure was 11.7%, and complications were more likely to occur in patients with high age, high BMI and comorbidity. Overall DAOH during the first year after intervention was 343 days, lowest amongst patients with tracheobronchomalacia or severe airway stenosis, and in those who underwent endoscopic stent insertion. Conclusion Endoscopic treatment is a safe and viable intervention in the management of benign central airway obstruction in adults with few complications and a high overall outcome. |
| Τύπος εγγράφου: | Article Other literature type |
| Περιγραφή αρχείου: | application/pdf |
| Γλώσσα: | English |
| ISSN: | 1434-4726 0937-4477 |
| DOI: | 10.1007/s00405-025-09230-1 |
| Σύνδεσμος πρόσβασης: | https://pubmed.ncbi.nlm.nih.gov/39979626 https://vbn.aau.dk/da/publications/9cd66eb1-f283-4eea-8ac9-b081074fc025 https://vbn.aau.dk/ws/files/773316418/B_gh_et_al._2025_._Patient-centred_outcome_following_endoscopic_management_of_benign_central_airway_obstruction.pdf http://www.scopus.com/inward/record.url?scp=85218674466&partnerID=8YFLogxK https://doi.org/10.1007/s00405-025-09230-1 http://www.scopus.com/inward/record.url?scp=85218674466&partnerID=8YFLogxK https://pure.au.dk/portal/en/publications/c2234b59-bf57-4962-976f-10e6fe8cecd4 https://doi.org/10.1007/s00405-025-09230-1 |
| Rights: | CC BY |
| Αριθμός Καταχώρησης: | edsair.doi.dedup.....c39fb7b194b05be7d36c86f2b2e2a954 |
| Βάση Δεδομένων: | OpenAIRE |
| ISSN: | 14344726 09374477 |
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| DOI: | 10.1007/s00405-025-09230-1 |