Academic Journal
Long-term continuous exercise training counteracts the negative impact of the menopause transition on cardiometabolic health in hypertensive women - a 9-year RCT follow-up
| Title: | Long-term continuous exercise training counteracts the negative impact of the menopause transition on cardiometabolic health in hypertensive women - a 9-year RCT follow-up |
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| Authors: | Mohr, Magni, Sjúrðarson, Tórur, Skoradal, May Britt, Nordsborg, Nikolai B., Krustrup, Peter |
| Source: | Mohr, M, Sjúrðarson, T, Skoradal, M B, Nordsborg, N B & Krustrup, P 2024, ' Long-term continuous exercise training counteracts the negative impact of the menopause transition on cardiometabolic health in hypertensive women : a 9-year RCT follow-up ', Progress in Cardiovascular Diseases, vol. 85, pp. 54-62 . https://doi.org/10.1016/j.pcad.2023.12.001 |
| Publisher Information: | Elsevier BV, 2024. |
| Publication Year: | 2024 |
| Subject Terms: | Adult, Aging, Time Factors, Football, Soccer, Humans, 2. Zero hunger, Hypertension/physiopathology, Prevention, Cardiometabolic Risk Factors, Middle Aged, 16. Peace & justice, Exercise Therapy/methods, Exercise Therapy, 3. Good health, Treatment, Cardiovascular diseases, Treatment Outcome, Hypertension, Female, Menopause, Sedentary Behavior, Risk Reduction Behavior, Biomarkers/blood, Biomarkers, Follow-Up Studies |
| Description: | The study examined effects of 9-yrs of multicomponent exercise training during the menopause interval on cardiometabolic health in hypertensive women.Sedentary, middle-aged women (n = 25) with mild-to-moderate arterial hypertension were randomized into a soccer training (multicomponent exercise; EX; n = 12) or control group (CON; n = 13). EX took part in 1-h football training sessions, 1-3 times weekly, for a consecutive 9-years, totaling ∼800 training sessions, while CON did not take part in regular exercise training. 22 participants entered menopause during the intervention.A time×group interaction effect (P = 0.04) of 8.5 mmHg in favour of EX was observed for changes in mean arterial pressure (MAP) (EX: -4.8 [-10.7;1.1] mmHg, CON +3.7 [-2.0;9.3] mmHg). Time×group interaction effects in favour of EX were also observed for total body weight (4.6 kg, P = 0.008, EX: +0.7 [-1.7;3.0] kg, CON: +5.3 [3.0;7.6] kg, total fat percentage (5.7%-points, P = 0.02; EX (-1.9 [-4.4;0.6] %-points; P = 0.13), CON +3.8 [1.4;6.2] %-points and for total cholesterol (1.2 mmol/l, P = 0.03, EX: -0.5 [-1.0;-0.1] mmol/l, CON: +0.7 [0.2;1.1] mmol/l. EX reduced (P = 0.02) plasma low-density lipoprotein cholesterol by -0.4 [-0.8;-0.1] mmol/l, whereas an increase (P = 0.01) of 0.4 [0.1;0.8] mmol/l occurred in CON (interaction. P |
| Document Type: | Article |
| File Description: | application/pdf |
| Language: | English |
| ISSN: | 0033-0620 |
| DOI: | 10.1016/j.pcad.2023.12.001 |
| Access URL: | https://pubmed.ncbi.nlm.nih.gov/38070694 https://curis.ku.dk/ws/files/403384708/1_s2.0_S0033062023001238_main.pdf |
| Rights: | CC BY NC ND |
| Accession Number: | edsair.doi.dedup.....aa1e42436d41a93a6a4e5f3dc4cc2c2e |
| Database: | OpenAIRE |
| ISSN: | 00330620 |
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| DOI: | 10.1016/j.pcad.2023.12.001 |