Academic Journal
How does the macroenvironment influence brain and behaviour – a review of current status and future perspectives
| Title: | How does the macroenvironment influence brain and behaviour – a review of current status and future perspectives |
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| Authors: | Polemiti, Elli, Hese, Sören, Schepanski, Kerstin, Yuan, Jiacan, environMENTAL consortium, Schumann, Gunter |
| Source: | medRxiv Mol Psychiatry Molecular Psychiatry medRxiv [Preprint] |
| Publication Status: | Preprint |
| Publisher Information: | Cold Spring Harbor Laboratory, 2023. |
| Publication Year: | 2023 |
| Subject Terms: | Expert Review, Climate Change [MeSH], Humans [MeSH], Mental Health [MeSH], Brain/physiology [MeSH], 692/699/476, Mental Disorders [MeSH], expert-review, 631/477, Neuroimaging/methods [MeSH], Behavior/physiology [MeSH], Environment [MeSH], 631/378, Behavior, Mental Disorders, Climate Change, Brain, Neuroimaging, Environment, 15. Life on land, Article, 3. Good health, Mental Health, 13. Climate action, 11. Sustainability, Humans, 14. Life underwater |
| Description: | The environment influences mental health, both detrimentally and beneficially. Current research has emphasized the individual psychosocial ‘microenvironment’. Less attention has been paid to ‘macro-environmental’ challenges including climate change, pollution, urbanicity and socioeconomic disparity. With the advent of large-scale big-data cohorts and an increasingly dense mapping of macroenvironmental parameters, we are now in a position to characterise the relation between macroenvironment, brain, and behaviour across different geographic and cultural locations globally. This review synthesises findings from recent epidemiological and neuroimaging studies, aiming to provide a comprehensive overview of the existing evidence between the macroenvironment and the structure and functions of the brain, with a particular emphasis on its implications for mental illness. We discuss putative underlying mechanisms and address the most common exposures of the macroenvironment. Finally, we identify critical areas for future research to enhance our understanding of the aetiology of mental illness and to inform effective interventions for healthier environments and mental health promotion. |
| Document Type: | Article Other literature type |
| ISSN: | 1476-5578 1359-4184 |
| DOI: | 10.1101/2023.10.09.23296785 |
| DOI: | 10.1038/s41380-024-02557-x |
| Access URL: | https://pubmed.ncbi.nlm.nih.gov/38658771 https://pubmed.ncbi.nlm.nih.gov/37873310 https://repository.publisso.de/resource/frl:6509459 |
| Rights: | CC BY URL: http://creativecommons.org/licenses/by-nd/4.0/This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License (http://creativecommons.org/licenses/by-nd/4.0/) , which allows reusers to copy and distribute the material in any medium or format in unadapted form only, and only so long as attribution is given to the creator. The license allows for commercial use. |
| Accession Number: | edsair.doi.dedup.....a1e4fe4d328b3751ae38dec9bb58db73 |
| Database: | OpenAIRE |
| ISSN: | 14765578 13594184 |
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| DOI: | 10.1101/2023.10.09.23296785 |