Academic Journal
Naphthalimide coupled histidine based fluorescent approach towards the recognition of p-hydroxybenzoic acid: a biomarker
| Title: | Naphthalimide coupled histidine based fluorescent approach towards the recognition of p-hydroxybenzoic acid: a biomarker |
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| Authors: | Monika Bhattu, Deepika Kathuria, Vishal Mutreja, Meenakshi Verma |
| Source: | International Journal of Environmental Analytical Chemistry. 104:6579-6591 |
| Publisher Information: | Informa UK Limited, 2022. |
| Publication Year: | 2022 |
| Subject Terms: | 02 engineering and technology, 0210 nano-technology, 01 natural sciences, 3. Good health, 0104 chemical sciences |
| Description: | Recognition of disease biomarkers are crucial to predict the outbursts of certain diseases thus avoiding harmful effects of disease. Thus, discovering new methods for fast and precise detection is need of the hour. In this recent work, a novel naphthalimide coupled histidine-based fluorescent organic cation was synthesised. The synthesised organic cation has been processed into its fluorescent aggregates employing SDS and SDBS as anionic surfactants. It was observed that the developed fluorescent aggregates exhibit aggregation-induced emission enhancement (AIEE). The aggregates (4/SDBS) display considerable change in the fluorescent profile in presence of p-hydroxybenzoic acid, a biomarker for tuberculosis (TB) and gastric cancer, which is modulated by aggregation – disaggregation process. However, the individual 4 has not shown any response in emission profile on addition of p-hydroxybenzoic acid thus, it was hypothesised that imidazolium cation actively contributed towards the recognition of TB biomarker. The limit of detection was calculated 55 nM using 3σmethod. |
| Document Type: | Article Other literature type |
| Language: | English |
| ISSN: | 1029-0397 0306-7319 |
| DOI: | 10.1080/03067319.2022.2149329 |
| DOI: | 10.6084/m9.figshare.21655844.v1 |
| DOI: | 10.6084/m9.figshare.21655844 |
| Rights: | CC BY |
| Accession Number: | edsair.doi.dedup.....755e1ccafe15c73086b2940340b164be |
| Database: | OpenAIRE |
| ISSN: | 10290397 03067319 |
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| DOI: | 10.1080/03067319.2022.2149329 |