Academic Journal
The impact of thrombophilia on in-hospital outcomes in patients with acute coronary syndrome: insights from the United States National Inpatient Sample
| Title: | The impact of thrombophilia on in-hospital outcomes in patients with acute coronary syndrome: insights from the United States National Inpatient Sample |
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| Authors: | Chun Shing Kwok, Tom Gibbs, Malik Majeed, Josip Andelo Borovac, Maximilian Will, Konstantin Schwarz, Muhammed Ayyaz Ul Haq, Gregory Y. H. Lip, Adnan Qureshi, Eric Holroyd |
| Source: | Kwok, C S, Gibbs, T, Majeed, M, Borovac, J A, Will, M, Schwarz, K, Haq, M A U, Lip, G Y H, Qureshi, A & Holroyd, E 2025, 'The impact of thrombophilia on in-hospital outcomes in patients with acute coronary syndrome: insights from the United States National Inpatient Sample', Journal of Thrombosis and Thrombolysis, vol. 58, no. 2, pp. 178-187. https://doi.org/10.1007/s11239-025-03068-4 |
| Publisher Information: | Springer Science and Business Media LLC, 2025. |
| Publication Year: | 2025 |
| Subject Terms: | Male, Cost, Inpatients/statistics & numerical data, outcomes, Acute Coronary Syndrome/mortality, length of stay, Hospital Costs/statistics & numerical data, cost, Prevalence, Humans, Thrombophilia, acute coronary syndromes, Hospital Mortality, Mortality, Acute Coronary Syndrome, Hospital Costs, thrombophilia, Aged, Retrospective Studies, national inpatient sample, Inpatients, percutaneous coronary intervention, NIS, Middle Aged, Length of Stay, ACS, United States/epidemiology, mortality, United States, Hospitalization, Length of Stay/statistics & numerical data, Length of stay, Female, Acute coronary syndrome |
| Description: | The prevalence of thrombophilia among patients who are hospitalized with acute coronary syndrome (ACS) and whether the condition affects outcomes is unknown. We conducted a retrospective cohort study of patients hospitalized with ACS by analyzing data from the United State National Inpatient Sample (NIS) between 2016 and 2021. Multiple logistic and linear regressions were used to determine the association between thrombophilia and in-hospital mortality, length of stay and cost. There were a total of 5,627,065 hospital admissions with ACS and 43,040 had thrombophilia (0.76%). Patients with thrombophilia were younger (median age 66 vs. 69 years, p |
| Document Type: | Article |
| Language: | English |
| ISSN: | 1573-742X |
| DOI: | 10.1007/s11239-025-03068-4 |
| Access URL: | https://pubmed.ncbi.nlm.nih.gov/39954039 http://www.scopus.com/inward/record.url?scp=85218213678&partnerID=8YFLogxK https://vbn.aau.dk/da/publications/3ba77617-a05b-40d2-8793-c68bc4a8c209 https://doi.org/10.1007/s11239-025-03068-4 |
| Rights: | Springer Nature TDM |
| Accession Number: | edsair.doi.dedup.....59ab4c1eabaa3f1bb49c669f94562a8b |
| Database: | OpenAIRE |
| ISSN: | 1573742X |
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| DOI: | 10.1007/s11239-025-03068-4 |