Academic Journal
Genetic components of functional connectivity in the brain: The heritability of synchronization likelihood: the heritability of synchronization likelihood
| Τίτλος: | Genetic components of functional connectivity in the brain: The heritability of synchronization likelihood: the heritability of synchronization likelihood |
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| Συγγραφείς: | Posthuma, Danielle, de Geus, Eco J C, Mulder, Elles J C M, Smit, Dirk J A, Boomsma, Dorret I, Stam, Cornelis J |
| Πηγή: | Posthuma, D, de Geus, E J C, Mulder, E J C M, Smit, D J A, Boomsma, D I & Stam, C J 2005, 'Genetic components of functional connectivity in the brain : the heritability of synchronization likelihood', Human Brain Mapping, vol. 26, no. 3, pp. 191-8. https://doi.org/10.1002/hbm.20156 |
| Στοιχεία εκδότη: | Wiley, 2005. |
| Έτος έκδοσης: | 2005 |
| Θεματικοί όροι: | Netherlands Twin Register (NTR), Male, 0301 basic medicine, Genetic Predisposition to Disease/genetics, Inheritance Patterns, Brain, Environment, Neural Pathways/growth & development, Alpha Rhythm, 03 medical and health sciences, Cognition, 0302 clinical medicine, Inheritance Patterns/physiology, Neural Pathways, Humans, Female, Genetic Predisposition to Disease, Genetic Testing, Brain/growth & development, Cortical Synchronization, Cognition/physiology |
| Περιγραφή: | Cognitive functions require the integrated activity of multiple specialized, distributed brain areas. Such functional coupling depends on the existence of anatomical connections between the various brain areas as well as physiological processes whereby the activity in one area influences the activity in another area. Recently, the Synchronization Likelihood (SL) method was developed as a general method to study both linear and nonlinear aspects of coupling. In the present study the genetic architecture of the SL in different frequency bands was investigated. Using a large genetically informative sample of 569 subjects from 282 extended twin families we found that the SL is moderately to highly heritable (41–67%) especially in the alpha frequency (8–13 Hz) range. This index of functional connectivity of the brain has been associated with a number of pathological states of the brain. The significant heritability found here suggests that SL can be used to examine the genetic susceptibility to these conditions. Hum Brain Mapp, 2005. © 2005 Wiley‐Liss, Inc. |
| Τύπος εγγράφου: | Article |
| Γλώσσα: | English |
| ISSN: | 1097-0193 1065-9471 |
| DOI: | 10.1002/hbm.20156 |
| Σύνδεσμος πρόσβασης: | https://europepmc.org/articles/pmc6871713?pdf=render https://pubmed.ncbi.nlm.nih.gov/15929086 https://hdl.handle.net/1871/17998 https://doi.org/10.1002/hbm.20156 https://research.vu.nl/en/publications/20cb1dd8-f010-4d53-82b4-6ee2fbeb7683 https://research.vu.nl/en/publications/genetic-components-of-functional-connectivity-in-the-brain-the-he https://www.narcis.nl/publication/RecordID/oai%3Aresearch.vu.nl%3Apublications%2F20cb1dd8-f010-4d53-82b4-6ee2fbeb7683 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6871713 https://onlinelibrary.wiley.com/doi/abs/10.1002/hbm.20156 https://researchinformation.amsterdamumc.org/en/publications/genetic-components-of-functional-connectivity-in-the-brain-the-he https://www.growkudos.com/publications/10.1002%252Fhbm.20156/reader https://research.vumc.nl/en/publications/2e590c30-82ca-447e-8eb4-ac33500eb127 https://pure.amsterdamumc.nl/en/publications/c56714d1-61c6-4e79-9b46-4b257ba881db https://doi.org/10.1002/hbm.20156 |
| Rights: | Wiley Online Library User Agreement |
| Αριθμός Καταχώρησης: | edsair.doi.dedup.....27e25dfc8037a33359477e8db7f8e9f2 |
| Βάση Δεδομένων: | OpenAIRE |
| ISSN: | 10970193 10659471 |
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| DOI: | 10.1002/hbm.20156 |