Variation in cystectomy pathology reporting practice—results from an international survey of 212 pathologists

Bibliographic Details
Title: Variation in cystectomy pathology reporting practice—results from an international survey of 212 pathologists
Authors: Jon Griffin, Arndt Hartmann, Eva Comperat
Source: Virchows Arch
Publisher Information: Springer Science and Business Media LLC, 2024.
Publication Year: 2024
Subject Terms: Pathologists, Bladder cancer, Surveys and Questionnaires [MeSH], Humans [MeSH], Tissue Fixation/methods [MeSH], Urinary Bladder Neoplasms/pathology [MeSH], Cystectomy [MeSH], Neoplasm, Residual/pathology [MeSH], Pathological response score, Cystectomy, Health Care Surveys [MeSH], Pathologists [MeSH], Original Article, Urinary Bladder Neoplasms/surgery [MeSH], Grossing, Practice Patterns, Physicians'/statistics, Dissection, Neoadjuvant chemotherapy, Pathology, Surgical/methods [MeSH], Neoplasm, Residual, Tissue Fixation, Urinary Bladder Neoplasms, Pathology, Surgical, Health Care Surveys, Surveys and Questionnaires, Humans, Practice Patterns, Physicians'
Description: The pathological assessment of cystectomy specimens is important for accurate prognostic information and to inform adjuvant therapy decisions. However, there is limited evidence regarding the best approach to fixation, dissection, block selection and microscopic assessment of cystectomies. We report the results of an international survey of 212 pathologists and their approach to cystectomy pathology. There is variation at all stages of the specimen journey including in fixation and dissection techniques, and in the approach to evaluating residual tumour. This is particularly evident in the post-neoadjuvant chemotherapy setting where there is variable use of response scoring systems and differing approaches to sampling. We also find variation in the use of digital and molecular pathology in cystectomy specimens. Finally, we have suggested areas for future research in cystectomy pathological assessment.
Document Type: Article
Other literature type
Language: English
ISSN: 1432-2307
0945-6317
DOI: 10.1007/s00428-024-03924-3
Access URL: https://pubmed.ncbi.nlm.nih.gov/39243298
https://repository.publisso.de/resource/frl:6503095
Rights: CC BY
Accession Number: edsair.doi.dedup.....19327c62876fce9076b645024edcb1dd
Database: OpenAIRE
Description
ISSN:14322307
09456317
DOI:10.1007/s00428-024-03924-3