Academic Journal
An Expert Opinion on the Role of the Rosuvastatin/Amlodipine Single Pill Fixed Dose Combination in Cardiovascular Prevention
| Title: | An Expert Opinion on the Role of the Rosuvastatin/Amlodipine Single Pill Fixed Dose Combination in Cardiovascular Prevention |
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| Authors: | Gallo, Giovanna, Sarzani, Riccardo, Cicero, Arrigo Francesco Giuseppe, Genovese, Stefano, Pirro, Matteo, Gallelli, Luca, Faggiano, Andrea, Volpe, Massimo |
| Source: | High Blood Press Cardiovasc Prev |
| Publisher Information: | Springer Science and Business Media LLC, 2023. |
| Publication Year: | 2023 |
| Subject Terms: | Dyslipidaemia, cardiovascular prevention, dyslipidaemia, fixed dose combination, hypertension, rosuvastatin/amlodipine, Fixed dose combination, 3. Good health, Rosuvastatin/Amlodipine, Cardiovascular prevention, Hypertension, Drug Combinations, Cardiovascular Diseases, Humans, Amlodipine, Rosuvastatin Calcium, Consensus Document, Antihypertensive Agents |
| Description: | Current cardiovascular disease prevention strategies are based on the management of cardiovascular risk as a continuum, redefining the therapeutic goals for each individual based on the estimated global risk profile. Given the frequent clustering of the principal cardiovascular risk factors, such as hypertension, diabetes and dyslipidaemia, in the same individual, patients are required to take multiple drugs to achieve therapeutic targets. The adoption of single pill fixed dose combinations may contribute to achieve better control of blood pressure and cholesterol compared to the separate administration of the individual drugs, mostly due to better adherence related to therapeutic simplicities. This paper reports the outcomes of an Expert multidisciplinary Roundtable. In particular, the rational and potential clinical use of the single pill fixed dose combination "Rosuvastatin-Amlodipine" for the management of concomitant hypertension/hypercholesterolemia in different clinical fields are discussed. This Expert Opinion also illustrates the importance of an early and effective management of total cardiovascular risk, highlights the substantial benefits of combining blood pressure and lipid-lowering treatments in a single-pill fixed dose combination and attempts to identify and overcome the barriers to the implementation in clinical practice of the fixed dose combinations with dual targets. This Expert Panel identifies and proposes the categories of patients who may benefit the most from this fixed dose combination. |
| Document Type: | Article Other literature type |
| File Description: | application/pdf |
| Language: | English |
| ISSN: | 1179-1985 |
| DOI: | 10.1007/s40292-023-00570-9 |
| Access URL: | https://pubmed.ncbi.nlm.nih.gov/37020154 https://hdl.handle.net/11573/1691027 https://doi.org/10.1007/s40292-023-00570-9 https://hdl.handle.net/11391/1548735 https://doi.org/10.1007/s40292-023-00570-9 https://pubmed.ncbi.nlm.nih.gov/37020154/ https://hdl.handle.net/11585/937915 https://doi.org/10.1007/s40292-023-00570-9 |
| Rights: | CC BY NC URL: http://creativecommons.org/licenses/by-nc/4.0/Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (http://creativecommons.org/licenses/by-nc/4.0/) . |
| Accession Number: | edsair.doi.dedup.....15410d4ca1482967406c08546d81b78c |
| Database: | OpenAIRE |
| ISSN: | 11791985 |
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| DOI: | 10.1007/s40292-023-00570-9 |