Λεπτομέρειες βιβλιογραφικής εγγραφής
| Τίτλος: |
A Systematic Review of β-Lactamase and Carbapenemase-Producing Escherichia coli at the Animal–Food Interface in the Middle East and North Africa. |
| Συγγραφείς: |
Sodagari, Hamid Reza, Habib, Ihab |
| Πηγή: |
Veterinary Sciences; Sep2026, Vol. 13 Issue 9, p994, 19p |
| Θεματικοί όροι: |
Beta lactamases, Carbapenemase, Food animals, Drug resistance in microorganisms, Escherichia coli |
| Γεωγραφικοί όροι: |
Middle East, North Africa |
| Περίληψη: |
Simple Summary: Antimicrobial resistance is a growing global health problem that makes infections in humans and animals more difficult to treat. Food-producing animals and foods derived from animals may serve as potential reservoirs or vehicles for bacteria carrying antimicrobial resistance traits, which could contribute to the dissemination of resistance through the food production chain. This review examined published studies from the Middle East and North Africa region over the last 10 years to assess the occurrence of antimicrobial-resistant Escherichia coli in food animals and animal-derived foods. The findings showed that resistant bacteria have been reported in several countries, with poultry and seafood products identified as important sources of resistant E. coli. Genes associated with resistance to commonly used antibiotics were frequently detected, including genes that can make bacteria resistant to some of the most important medicines used for treating serious infections. These findings highlight the need for improved monitoring of antimicrobial resistance in food production systems and stronger collaboration between human, animal, and environmental health sectors. Enhanced surveillance and responsible antimicrobial use in animal production are essential to limit the emergence and spread of resistant bacteria and protect public health. Antimicrobial resistance is a major global health challenge, and food-producing animals and foods of animal origin may contribute to the dissemination of resistant bacteria through the food chain. This review aimed to summarize recent evidence on extended-spectrum β-lactamase- and carbapenemase-producing Escherichia coli in food animals and animal-derived foods across Middle East and North Africa countries. A structured literature search was conducted to identify peer-reviewed studies published between 2016 and 2025. Data regarding country, sample type, prevalence, and resistance genes were extracted and analyzed descriptively. Twenty-eight studies from nine MENA countries revealed the presence of resistant E. coli in poultry, cattle, sheep, swine, camels, seafood, and other animal-derived products. Poultry showed a higher reported prevalence of extended-spectrum β-lactamase-producing E. coli, while carbapenem-resistant isolates were less frequently reported but were detected in several countries. The blaCTX-M family was the predominant extended-spectrum β-lactamase determinant, whereas blaNDM, blaOXA-48-like, and blaKPC were among the commonly identified carbapenemase genes. These findings demonstrate that food animals and animal-derived foods may represent important reservoirs of clinically relevant resistance genes in the Middle East and North Africa region. Strengthening One Health surveillance, antimicrobial stewardship, and regional collaboration is essential to limit the spread of resistant bacteria. [ABSTRACT FROM AUTHOR] |
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| Βάση Δεδομένων: |
Complementary Index |