Λεπτομέρειες βιβλιογραφικής εγγραφής
| Τίτλος: |
In Vitro and In Vivo Evaluation of Mung Bean Coat–Enriched Coffee for Potential Diabetes Management: Enzyme Inhibition and Impact on Postprandial Glycemia and Insulinaemia in Healthy Individuals. |
| Συγγραφείς: |
Pookate, Wassana, Trachootham, Dunyaporn, Suttisansanee, Uthaiwan, Essiedu, Justice Amakye, Santivarangkna, Chalat, Bose, Anupama |
| Πηγή: |
Journal of Food Biochemistry; 7/17/2026, Vol. 2026, p1-10, 10p |
| Θεματικοί όροι: |
Enzyme inhibitors, Alpha-glucosidases, Hyperinsulinism, Treatment of diabetes, CD26 antigen, Hyperglycemia, Mung bean, Coffee |
| Περίληψη: |
This study investigated the in vitro α‐glucosidase (α‐GLU) and dipeptidyl peptidase‐IV (DPP‐IV) inhibition by mung bean fractions and red kidney bean (RKB) and tested the effect of a mung bean coat (MBC)–enriched coffee blend on postprandial glucose and insulin responses in healthy individuals. The mung bean fraction, particularly its seed coat, showed significantly higher inhibition of α‐GLU (74.20%) and DPP‐IV (55.42%) than all tested RKB samples. Blends of MBC‐enriched coffee were formulated by combining roasted MBC with coffee powder at different ratios. The 75:25 blend exhibited the highest enzyme inhibition (27.10% α‐GLU and 68.93% DPP‐IV inhibition). A 50:50 blend was selected for clinical testing based on its sensory appeal. In the randomized crossover in vivo trial, MBC‐enriched coffee significantly reduced postprandial glucose levels by 6.5 and 5.5 mg/dL at 15 and 30 min and insulin levels by 30.78, 29.36, and 25.92 µIU/mL at 15, 30, and 60 min, respectively, compared to control coffee. These findings suggest that MBC could be an ingredient for managing blood glucose levels in functional products. [ABSTRACT FROM AUTHOR] |
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| Βάση Δεδομένων: |
Complementary Index |