Academic Journal
Acupuncture is associated with lower accidental injury risk among patients with Parkinson's disease: a nationwide retrospective cohort study.
| Τίτλος: | Acupuncture is associated with lower accidental injury risk among patients with Parkinson's disease: a nationwide retrospective cohort study. |
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| Συγγραφείς: | Chou HJ; Department of Chinese Medicine, Taipei City Hospital, Taipei, Taiwan.; Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University, Taipei, Taiwan., Wang MJ; Department of Chinese Medicine, Taipei City Hospital, Taipei, Taiwan.; Institute of Traditional Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Lin SK; Department of Chinese Medicine, Taipei City Hospital, Taipei, Taiwan.; Institute of Traditional Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Public Health, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; General Education Center, University of Taipei, Taipei, Taiwan. |
| Πηγή: | Frontiers in neurology [Front Neurol] 2026 Sep 30; Vol. 17, pp. 1889885. Date of Electronic Publication: 2026 Sep 30 (Print Publication: 2026). |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101546899 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-2295 (Electronic) Linking ISSN: 16642295 NLM ISO Abbreviation: Front Neurol Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: [Lausanne : Frontiers Research Foundation, 2010]- |
| Ιατρικοί όροι (MeSH): | Parkinson Disease*/therapy , Parkinson Disease*/epidemiology , Accidental Falls*/statistics & numerical data , Accidental Falls*/prevention & control , Accidental Injuries*/epidemiology , Accidental Injuries*/prevention & control , Acupuncture Therapy*, Taiwan/epidemiology ; Humans ; Male ; Female ; Retrospective Studies ; Aged ; Middle Aged ; Cohort Studies |
| Περίληψη: | Background: Patients with Parkinson's disease (PD) have a high risk of accidental injuries because motor and non-motor symptoms can impair gait, balance, cognition, and autonomic function. Acupuncture has been reported to improve gait and balance, but its association with long-term injury prevention in PD remains unclear. Methods: We conducted a nationwide retrospective cohort study using Taiwan's National Health Insurance Research Database. Patients newly diagnosed with PD between 2001 and 2012 were followed through 2018. Propensity score matching (PSM) was used to improve comparability between patients who received acupuncture and those who did not. The PSM cohort was designated as the primary analysis, and a multivariable analysis of the full cohort was supportive. Cox proportional hazards models estimated adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs). Results: Among 24,467 patients with PD, 7,830 (32.0%) received acupuncture. Accidental injuries occurred in 15.2% of patients in the acupuncture group and 17.1% of patients in the non-acupuncture group. In the primary PSM analysis, acupuncture was associated with a lower risk of hospitalization for accidental injury (aHR, 0.67; 95% CI, 0.42-0.85). The association was strongest for accidental falls, although no simple dose-response relationship was observed across acupuncture-session categories. The supportive full-cohort analysis yielded a similar direction of association (aHR, 0.60; 95% CI, 0.39-0.76). Conclusion: In this nationwide claims-based cohort, acupuncture use was associated with a lower risk of hospitalization for accidental injury among patients newly diagnosed with PD. Because residual confounding and differences in care-seeking may remain, prospective studies with clinical measures of PD severity are warranted. (Copyright © 2026 Chou, Wang and Lin.) |
| Competing Interests: | The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. |
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| Contributed Indexing: | Keywords: Nationwide cohort; Parkinson’s disease; Taiwan; accidental injury; acupuncture; falls; public health; real-world evidence |
| Entry Date(s): | Date Created: 20261015 Date Completed: 20261015 Latest Revision: 20261016 |
| Update Code: | 20261016 |
| PubMed Central ID: | PMC13661429 |
| DOI: | 10.3389/fneur.2026.1889885 |
| PMID: | 42876775 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1664-2295 |
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| DOI: | 10.3389/fneur.2026.1889885 |