Academic Journal
Effect of Visual Crowding on Quality of Life in Glaucoma Patients.
| Τίτλος: | Effect of Visual Crowding on Quality of Life in Glaucoma Patients. |
|---|---|
| Συγγραφείς: | Guerreiro-Filho M; Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States.; Department of Ophthalmology and Visual Sciences, Paulista School of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil., Malek DA; Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States., Azizi A; Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States., Tavares IM; Department of Ophthalmology and Visual Sciences, Paulista School of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil., Medeiros FA; Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States. |
| Πηγή: | Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2026 Oct 01; Vol. 67 (12), pp. 13. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE |
| Imprint Name(s): | Publication: Brookline Ma : Association For Research In Vision And Ophthalmology (Arvo) Original Publication: St. Louis, Mosby. |
| Ιατρικοί όροι (MeSH): | Visual Fields*/physiology , Glaucoma, Open-Angle*/physiopathology , Glaucoma, Open-Angle*/psychology , Vision Disorders*/physiopathology , Vision Disorders*/psychology , Quality of Life*, Visual Acuity/physiology ; Intraocular Pressure/physiology ; Humans ; Cross-Sectional Studies ; Female ; Male ; Aged ; Visual Field Tests ; Surveys and Questionnaires ; Middle Aged ; Sickness Impact Profile |
| Περίληψη: | Purpose: To investigate the association between visual crowding and vision-related quality of life (QoL) in patients with glaucoma. Methods: This cross-sectional study included 50 patients diagnosed with POAG. Visual crowding was quantified by measuring the critical spacing (Scritical). The Scritical was assessed in each visual field quadrant. For each eye, a global Scritical was calculated as the mean of the eligible quadrant-specific values. Vision-related QoL was assessed using the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25), scored using Rasch analysis. Associations between the Scritical and the NEI VFQ-25 Rasch-calibrated scores were examined using generalized estimating equations, with multivariable models adjusted for age and standard automated perimetry 24-2 mean deviation. Results: Among 50 patients with POAG (93 eyes; mean age, 67.9 ± 9.2 years), the mean Rasch-calibrated NEI VFQ-25 score was 59.9 ± 18.8. In univariable analyses, each 1-degree increase in the better-eye global Scritical was associated with a 5.69-point lower NEI VFQ-25 score (95% confidence interval, -10.43 to -0.96; P = 0.018), and each 1-degree increase in the worse-eye Scritical was associated with a 2.23-point lower score (95% confidence interval, -4.38 to -0.08; P = 0.042). In multivariable analysis adjusting for age and standard automated perimetry mean deviation, the better-eye Scritical remained independently associated with a worse QoL (-5.02 points per degree; 95% confidence interval, -9.59 to -0.45; P = 0.031). Conclusions: Visual crowding is independently associated with worse vision-related QoL in patients with glaucoma, even after adjustment for standard perimetric loss. These findings suggest that visual crowding captures clinically meaningful aspects of visual dysfunction beyond conventional perimetry. |
| References: | Trends Cogn Sci. 2011 Apr;15(4):160-8. (PMID: 21420894) Eye (Lond). 2010 Dec;24(12):1759-69. (PMID: 21057519) Transl Vis Sci Technol. 2024 Sep 3;13(9):8. (PMID: 39235398) Int J Dev Neurosci. 2001 Apr;19(2):209-18. (PMID: 11255034) Vis Neurosci. 2006 Jan-Feb;23(1):137-42. (PMID: 16597357) J Vis. 2014 May 05;14(5):3. (PMID: 24799622) J Vis. 2020 Jun 3;20(6):1. (PMID: 32492098) Invest Ophthalmol Vis Sci. 2012 Jan 25;53(1):224-7. (PMID: 22159015) Ophthalmology. 2017 Nov;124(11):1612-1620. (PMID: 28676280) Nature. 1996 Sep 26;383(6598):334-7. (PMID: 8848045) Sci Rep. 2019 Dec 2;9(1):18113. (PMID: 31792321) JAMA Ophthalmol. 2015 Apr;133(4):384-90. (PMID: 25569808) J Vis. 2017 Sep 1;17(11):11. (PMID: 28973564) Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3827-3836. (PMID: 30737290) Br J Ophthalmol. 2016 Nov;100(11):1585-1590. (PMID: 27503395) Sci Rep. 2021 Mar 1;11(1):4843. (PMID: 33649371) Invest Ophthalmol Vis Sci. 2022 Jan 3;63(1):36. (PMID: 35084432) J Vis. 2009 Jun 29;9(6):18.1-15. (PMID: 19761309) J Glaucoma. 2021 Feb 1;30(2):140-147. (PMID: 33074958) Invest Ophthalmol Vis Sci. 2017 Nov 1;58(13):5810-5818. (PMID: 29131903) Arch Ophthalmol. 2001 Jul;119(7):1050-8. (PMID: 11448327) Optom Vis Sci. 2013 Aug;90(8):745-53. (PMID: 23851305) Expert Rev Pharmacoecon Outcomes Res. 2011 Oct;11(5):571-85. (PMID: 21958102) Invest Ophthalmol Vis Sci. 2012 Jun 14;53(7):3629-37. (PMID: 22511628) Invest Ophthalmol Vis Sci. 2008 Jul;49(7):3035-41. (PMID: 18326696) Ophthalmic Physiol Opt. 2011 May;31(3):225-32. (PMID: 21470272) Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):538-543. (PMID: 30716149) Arch Ophthalmol. 2000 Sep;118(9):1187-94. (PMID: 10980763) Vision Res. 2013 Apr 19;82:42-51. (PMID: 23485426) Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6540-8. (PMID: 20671278) |
| Grant Information: | R01 EY036593 United States EY NEI NIH HHS |
| Entry Date(s): | Date Created: 20261007 Date Completed: 20261007 Latest Revision: 20261014 |
| Update Code: | 20261014 |
| PubMed Central ID: | PMC13657127 |
| DOI: | 10.1167/iovs.67.12.13 |
| PMID: | 42841590 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1552-5783 |
|---|---|
| DOI: | 10.1167/iovs.67.12.13 |