Academic Journal
Biomedical Research Images Manipulated by Generative AI to Alter Scientific Outcomes: Diagnostic Study of Human and Automated Detection.
| Τίτλος: | Biomedical Research Images Manipulated by Generative AI to Alter Scientific Outcomes: Diagnostic Study of Human and Automated Detection. |
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| Συγγραφείς: | Luo S; Department of Urology, China-Japan Friendship Hospital, Beijing, Beijing, China., Tang R; Department of Urology, Beijing Hospital, Beijing, China, 8613911036970.; National Center for Gerontology, Beijing Hospital, Beijing, China.; National Clinical Research Center for Gerontology, Beijing Hospital, Beijing, China.; The Key Laboratory of Geriatrics of NHC, Beijing Hospital, Beijing, China.; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital, Beijing, China., Chen Z; Department of Urology, Beijing Hospital, Beijing, China, 8613911036970.; National Center for Gerontology, Beijing Hospital, Beijing, China.; National Clinical Research Center for Gerontology, Beijing Hospital, Beijing, China.; The Key Laboratory of Geriatrics of NHC, Beijing Hospital, Beijing, China.; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital, Beijing, China., Wang J; Department of Urology, Beijing Hospital, Beijing, China, 8613911036970.; National Center for Gerontology, Beijing Hospital, Beijing, China.; National Clinical Research Center for Gerontology, Beijing Hospital, Beijing, China.; The Key Laboratory of Geriatrics of NHC, Beijing Hospital, Beijing, China.; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital, Beijing, China., Liu M; Department of Urology, Beijing Hospital, Beijing, China, 8613911036970.; National Center for Gerontology, Beijing Hospital, Beijing, China.; National Clinical Research Center for Gerontology, Beijing Hospital, Beijing, China.; The Key Laboratory of Geriatrics of NHC, Beijing Hospital, Beijing, China.; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital, Beijing, China., Wang J; Department of Urology, China-Japan Friendship Hospital, Beijing, Beijing, China., Ma L; Department of Intensive Care Medicine, The Second Hospital & The Second Clinical Medical College of Lanzhou University, No. 82 Cuiyingmen, Lanzhou, Gansu, 73003, China, 86 13893679654. |
| Πηγή: | Journal of medical Internet research [J Med Internet Res] 2026 Oct 02; Vol. 28, pp. e100710. Date of Electronic Publication: 2026 Oct 02. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: JMIR Publications Country of Publication: Canada NLM ID: 100959882 Publication Model: Electronic Cited Medium: Internet ISSN: 1438-8871 (Electronic) Linking ISSN: 14388871 NLM ISO Abbreviation: J Med Internet Res Subsets: MEDLINE |
| Imprint Name(s): | Publication: <2011- > : Toronto : JMIR Publications Original Publication: [Pittsburgh, PA? : s.n., 1999- |
| Ιατρικοί όροι (MeSH): | Biomedical Research* , Artificial Intelligence* , Image Processing, Computer-Assisted*, Humans ; Generative Artificial Intelligence ; Animals |
| Περίληψη: | Unlabelled: In a diagnostic study of 104 western blot and subcutaneous xenograft tumor images, a high-fidelity generative model produced forgeries that could alter the conclusions of a study; 24 PhD-level expert reviewers could not reliably distinguish the forgeries from authentic figures (mean accuracy 50.5%, SD 6.9%), while the best-performing commercial AI detector achieved only moderate discrimination (area under the curve 0.790, 95% CI 0.695-0.885), revealing critical vulnerabilities in current research-integrity safeguards. (© Shuhang Luo, Runhua Tang, Ziyin Chen, Jianye Wang, Ming Liu, Jianfeng Wang, Li Ma. Originally published in the Journal of Medical Internet Research (https://www.jmir.org).) |
| References: | Acta Neurochir (Wien). 2025 Aug 7;167(1):214. (PMID: 40773066) PeerJ. 2025 Feb 20;13:e18988. (PMID: 39989748) Health Sci Rep. 2025 Feb 19;8(2):e70200. (PMID: 39980823) Front Artif Intell. 2025 Sep 02;8:1644098. (PMID: 40964145) Medicine (Baltimore). 2024 Jul 5;103(27):e38811. (PMID: 38968491) JAMA. 2023 Feb 28;329(8):637-639. (PMID: 36719674) Saudi J Anaesth. 2023 Jul-Sep;17(3):401-406. (PMID: 37601525) Nature. 2023 Jun;618(7964):222-223. (PMID: 37258739) Sci Rep. 2025 Nov 23;15(1):44021. (PMID: 41276575) |
| Contributed Indexing: | Keywords: AI-generated image detection; GPT Images 2.0; GenAI; biomedical image manipulation; conclusion-oriented falsification; generative artificial intelligence; research integrity |
| Entry Date(s): | Date Created: 20261002 Date Completed: 20261002 Latest Revision: 20261005 |
| Update Code: | 20261005 |
| PubMed Central ID: | PMC13633064 |
| DOI: | 10.2196/100710 |
| PMID: | 42826371 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1438-8871 |
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| DOI: | 10.2196/100710 |