Academic Journal
Microfluidic pretreatment devices for milk safety at the point of care.
| Τίτλος: | Microfluidic pretreatment devices for milk safety at the point of care. |
|---|---|
| Συγγραφείς: | Tang R; College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science & Technology, Xi'an, 710021, P.R. China. tangruihua@sust.edu.cn.; National Demonstration Center for Experimental Light Chemistry Engineering Education, Shaanxi University of Science & Technology, Xi'an, 710021, People's Republic of China. tangruihua@sust.edu.cn., Li T; College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science & Technology, Xi'an, 710021, P.R. China.; National Demonstration Center for Experimental Light Chemistry Engineering Education, Shaanxi University of Science & Technology, Xi'an, 710021, People's Republic of China., He H; College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science & Technology, Xi'an, 710021, P.R. China., Chen K; College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science & Technology, Xi'an, 710021, P.R. China., Shi F; College of Life Sciences, Shihezi University, Shihezi, P.R. China., Zhang S; College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science & Technology, Xi'an, 710021, P.R. China.; National Demonstration Center for Experimental Light Chemistry Engineering Education, Shaanxi University of Science & Technology, Xi'an, 710021, People's Republic of China., Li Z; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, People's Republic of China. zedong@xjtu.edu.cn.; Bioinspired Engineering and Biomechanics Center (BEBC), Xi'an Jiaotong University, Xi'an, P.R. China. zedong@xjtu.edu.cn. |
| Πηγή: | Mikrochimica acta [Mikrochim Acta] 2026 Oct 01; Vol. 193 (10). Date of Electronic Publication: 2026 Oct 01. |
| Τύπος έκδοσης: | Journal Article; Review |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 7808782 Publication Model: Electronic Cited Medium: Internet ISSN: 1436-5073 (Electronic) Linking ISSN: 00263672 NLM ISO Abbreviation: Mikrochim Acta Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Wien ; New York : Springer-Verlag. |
| Ιατρικοί όροι (MeSH): | Milk*/chemistry , Microfluidic Analytical Techniques*/instrumentation , Microfluidic Analytical Techniques*/methods , Point-of-Care Systems* , Food Safety* , Lab-On-A-Chip Devices*, Food Contamination/analysis ; Animals ; Humans |
| Περίληψη: | Milk is a vital nutrient source, playing an essential role in maintaining normal physiological functions and safeguarding human health. However, milk consumption may expose individuals to residual contaminants such as antibiotics and environmental pollutants, which pose serious threats to human health. Currently, traditional milk pretreatment technologies hinder the rapid detection of milk residues due to their cumbersome procedures, operational complexity, prolonged processing time, and high dependence on specialized personnel. Microfluidic devices have emerged as a promising tool for food safety monitoring in resource-limited settings due to their simplicity, portability, and rapid processing capabilities. Nevertheless, the lack of systematic summaries on microfluidic device development for milk pretreatment limits their widespread application. To overcome these drawbacks, this review first presents the types and preparation methods of microfluidic devices employed in milk pretreatment. Subsequently, it summarizes the emerging applications of these devices in this field. Finally, the current challenges and prospects are discussed. (© 2026. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.) |
| Competing Interests: | Declarations. Competing interests: The authors declare no competing interests. Clinical trial number: Not applicable. Generative AI and AI‑assisted technologies: The figures and graphic abstract of this manuscript were not used by any artificial intelligence (AI) tools. |
| References: | Analyst. 2020 Nov 9;145(22):7320-7329. (PMID: 32902519) Food Chem. 2024 Jan 1;430:137072. (PMID: 37549624) J Dairy Sci. 2021 Jan;104(1):126-133. (PMID: 33189293) Food Chem. 2026 Mar 01;504:147956. (PMID: 41548277) Lab Chip. 2020 Mar 3;20(5):979-986. (PMID: 32003380) J Colloid Interface Sci. 2023 Dec 15;652(Pt A):518-528. (PMID: 37607414) Cureus. 2024 Aug 11;16(8):e66632. (PMID: 39258062) Food Chem. 2024 Dec 15;461:140843. (PMID: 39178549) Materials (Basel). 2022 Sep 21;15(19):. (PMID: 36233880) Talanta. 2024 Nov 1;279:126585. (PMID: 39053361) Nanoscale Adv. 2021 Mar 24;3(10):2918-2923. (PMID: 36134197) ACS Omega. 2024 Aug 21;9(35):37408-37416. (PMID: 39246469) Anal Chem. 2025 Jan 21;97(2):1457-1464. (PMID: 39783778) Sci Rep. 2023 Apr 13;13(1):6041. (PMID: 37055481) Food Chem. 2021 Aug 30;354:129501. (PMID: 33735696) J Dairy Sci. 2013 Oct;96(10):6199-212. (PMID: 23891300) J Dairy Sci. 2021 Mar;104(3):2465-2479. (PMID: 33455742) Food Chem. 2022 Aug 30;386:132753. (PMID: 35367801) Talanta. 2022 May 1;241:123242. (PMID: 35085991) Anal Chim Acta. 2019 Apr 11;1053:131-138. (PMID: 30712558) Int J Biol Macromol. 2018 Jun;112:737-744. (PMID: 29427684) Sci Total Environ. 2022 Dec 10;851(Pt 1):158161. (PMID: 35988597) Food Chem. 2023 Jan 30;400:134014. (PMID: 36084587) Int J Biol Macromol. 2025 May;306(Pt 3):141719. (PMID: 40043991) Macromolecules. 2020 Sep 22;53(18):7962-7969. (PMID: 32981970) RSC Adv. 2018 Mar 28;8(22):12173-12178. (PMID: 35539369) Nutr Metab (Lond). 2024 Oct 25;21(1):85. (PMID: 39456082) Vet World. 2022 May;15(5):1228-1236. (PMID: 35765484) ACS Omega. 2019 Sep 25;4(15):16591-16596. (PMID: 31616840) Biosens Bioelectron. 2025 Feb 15;270:116949. (PMID: 39591924) Food Chem. 2023 Jan 1;398:133848. (PMID: 35964572) ACS Omega. 2023 Jun 23;8(26):24010-24015. (PMID: 37426252) Food Chem. 2022 Oct 1;390:133173. (PMID: 35594772) Molecules. 2024 Jun 09;29(12):. (PMID: 38930811) J Food Sci Technol. 2024 Dec;61(12):2367-2376. (PMID: 39431183) Food Res Int. 2024 Sep;192:114680. (PMID: 39147535) J Dairy Sci. 2018 Dec;101(12):10929-10938. (PMID: 30268629) Anal Chem. 2019 Nov 5;91(21):13418-13426. (PMID: 31566960) Food Chem. 2018 Apr 25;246:437-441. (PMID: 29291870) Food Chem. 2024 Mar 30;437(Pt 1):137740. (PMID: 37871421) Talanta. 2025 Jan 1;281:126808. (PMID: 39260252) Mikrochim Acta. 2025 Jul 28;192(8):527. (PMID: 40719766) J Dairy Sci. 2023 Jun;106(6):3856-3867. (PMID: 37164860) Front Chem. 2021 Mar 24;9:653869. (PMID: 33842437) J Dairy Sci. 2023 Jan;106(1):84-95. (PMID: 36357206) BMC Chem. 2025 Apr 18;19(1):103. (PMID: 40251611) Sci Rep. 2020 Mar 13;10(1):4627. (PMID: 32170077) Food Chem. 2024 Jan 1;430:136934. (PMID: 37542961) J Sep Sci. 2025 Apr;48(4):e70126. (PMID: 40205661) Micromachines (Basel). 2020 Nov 24;11(12):. (PMID: 33255218) Mikrochim Acta. 2023 Sep 21;190(10):408. (PMID: 37733266) ACS Appl Mater Interfaces. 2020 Jun 3;12(22):25304-25315. (PMID: 32369334) Food Chem. 2021 Sep 15;356:129692. (PMID: 33819791) Small Methods. 2024 Nov;8(11):e2400155. (PMID: 38781604) BMC Microbiol. 2021 Jun 28;21(1):197. (PMID: 34182947) Crit Rev Food Sci Nutr. 2021;61(2):312-324. (PMID: 32106694) ACS Appl Mater Interfaces. 2019 Jan 30;11(4):4578-4587. (PMID: 30582798) Food Res Int. 2021 Sep;147:110450. (PMID: 34399452) Membranes (Basel). 2020 Jan 06;10(1):. (PMID: 31935853) ACS Omega. 2022 Sep 16;7(38):33783-33792. (PMID: 36188311) |
| Contributed Indexing: | Keywords: Lab on chip; Lab on paper; Microfluidic device; Milk pretreatment; Point-of-care testing |
| Entry Date(s): | Date Created: 20261001 Date Completed: 20261001 Latest Revision: 20261008 |
| Update Code: | 20261008 |
| DOI: | 10.1007/s00604-026-08430-8 |
| PMID: | 42821006 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1436-5073 |
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| DOI: | 10.1007/s00604-026-08430-8 |