Academic Journal
Detection of Anaplasma capra in Patients with Suspected Crimean-Congo Hemorrhagic Fever, Turkey, 2022.
| Τίτλος: | Detection of Anaplasma capra in Patients with Suspected Crimean-Congo Hemorrhagic Fever, Turkey, 2022. |
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| Συγγραφείς: | Altay K, Elaldi N, Erol U, Koksal B, Sahin OF, Pektas AN, Buyuktuna SA, Oz M, Kıymaz YC, Tasseten TN, Sakar HF, Bakir M |
| Πηγή: | Emerging infectious diseases [Emerg Infect Dis] 2026 Oct; Vol. 32 (10), pp. 1561-1570. |
| Τύπος έκδοσης: | Journal Article; Review |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Atlanta, GA : National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), [1995- |
| Ιατρικοί όροι (MeSH): | Hemorrhagic Fever, Crimean*/epidemiology , Hemorrhagic Fever, Crimean*/diagnosis , Hemorrhagic Fever, Crimean*/microbiology , Anaplasma*/genetics , Anaplasma*/isolation & purification , Anaplasma*/classification, Turkey/epidemiology ; Humans ; Phylogeny ; Animals ; Female ; Genotype ; Male ; Disease Outbreaks ; Goats |
| Περίληψη: | Anaplasma capra is a recently discovered bacterial tickborne pathogen that was first identified in goats in 2012 and later in humans in China in 2015. We detected and genetically characterized A. capra in adult patients with suspected Crimean-Congo hemorrhagic fever (CCHF) in Turkey during the 2022 outbreak. We screened all patients for A. capra by using nested PCR targeting the gltA and groEL genes. We confirmed CCHF by molecular and serological tests. Of 263 patients, 6 (2.28%) were positive for A. capra. Sequence analysis revealed 84.16%-100% gltA gene similarity and 90.24%-100% groEL gene similarity with GenBank entries. Phylogenetic analysis confirmed all A. capra gene sequences belonged to genotype 1. Our results demonstrate clinical evidence of genotype 1 A. capra infection in humans. Our findings highlight the need for clinicians to consider A. capra in the differential diagnosis of CCHF-like symptoms, especially in endemic areas. |
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| Contributed Indexing: | Keywords: Anaplasma capra; Crimean-Congo hemorrhagic fever; Turkey; Türkiye; bacteria; genotyping; gltA; groEL; tick-borne infection; vector-borne infections; viruses |
| SCR Organism: | Anaplasma capra |
| Entry Date(s): | Date Created: 20260929 Date Completed: 20260929 Latest Revision: 20261004 |
| Update Code: | 20261004 |
| PubMed Central ID: | PMC13632829 |
| DOI: | 10.3201/eid3210.251049 |
| PMID: | 42811011 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1080-6059 |
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| DOI: | 10.3201/eid3210.251049 |