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Regulation of Craving: Neural Correlates and the Role of Stress and Delay Discounting.

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Τίτλος: Regulation of Craving: Neural Correlates and the Role of Stress and Delay Discounting.
Συγγραφείς: Nickel-Grenke S; Dresden University of Technology, Faculty of Psychology, Dresden, Germany., Wüllhorst R; Dresden University of Technology, Faculty of Psychology, Dresden, Germany., Scherbaum S; Dresden University of Technology, Faculty of Psychology, Dresden, Germany., Schwarz K; Dresden University of Technology, Faculty of Psychology, Dresden, Germany., Endrass T; Dresden University of Technology, Faculty of Psychology, Dresden, Germany.
Πηγή: Addiction biology [Addict Biol] 2026 Oct; Vol. 31 (10), pp. e70190.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 9604935 Publication Model: Print Cited Medium: Internet ISSN: 1369-1600 (Electronic) Linking ISSN: 13556215 NLM ISO Abbreviation: Addict Biol Subsets: MEDLINE
Imprint Name(s): Publication: Hoboken, NJ : Wiley-Blackwell
Original Publication: Abingdon, Oxfordshire, UK ; Cambridge, MA : Carfax, c1996-
Ιατρικοί όροι (MeSH): Delay Discounting*/physiology , Craving*/physiology , Stress, Psychological*/physiopathology , Stress, Psychological*/psychology , Prefrontal Cortex*/physiopathology , Prefrontal Cortex*/diagnostic imaging, Ventral Striatum/physiopathology ; Ventral Striatum/diagnostic imaging ; Hydrocortisone/metabolism ; Dorsolateral Prefrontal Cortex/physiopathology ; Dorsolateral Prefrontal Cortex/diagnostic imaging ; Humans ; Male ; Magnetic Resonance Imaging ; Adult ; Young Adult ; Reward
Περίληψη: Regulation of craving (ROC) by focusing on long-term negative consequences of drug use has been shown to successfully reduce subjective craving. This process is supported by the dorsolateral prefrontal cortex (dlPFC), which exerts control over reward and value signals in the ventral striatum (VS) and ventromedial prefrontal cortex (vmPFC). As stress impairs cognitive control and addiction is characterized by altered value computations manifesting in delay discounting, we examined how these factors interact with ROC and its neural correlates to better understand the use of ROC in high-risk situations. Sixty-eight male smokers underwent a delay discounting task and either a stress (socially evaluated cold pressor task) or a control condition. They subsequently completed a ROC task during fMRI while focusing on (1) long-term negative consequences (LATER) versus (2) short-term positive consequences (NOW). We found lower subjective craving ratings and attenuated neural responses in the VS (t = 4.33, p = 0.012) and vmPFC (t = 5.79, p < 0.001), as well as higher activation in the dlPFC (t = 4.09, p = 0.038) in the LATER compared to the NOW strategy. Although no neural or behavioural difference in ROC was observed between stress and control groups, both individual stress (cortisol) and delay discounting were positively related to vmPFC activity (NOW > LATER). We replicated previous results on ROC. Importantly, the association of vmPFC signals with stress response and delay discounting suggests that enhancing ROC success may involve reinforcing changes in self-referentiality of future thoughts to subjective value of drug use.
(© 2026 The Author(s). Addiction Biology published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction.)
References: Nat Neurosci. 2023 Feb;26(2):316-325. (PMID: 36536243)
JAMA Psychiatry. 2022 Jul 1;79(7):641-650. (PMID: 35648415)
Psychopharmacology (Berl). 2006 Mar;184(3-4):577-88. (PMID: 16133128)
Psychoneuroendocrinology. 2009 Jan;34(1):2-18. (PMID: 19041187)
Eur Addict Res. 2012;18(3):103-9. (PMID: 22285929)
Psychol Addict Behav. 2022 Dec;36(8):1012-1022. (PMID: 35175067)
J Psychiatry Neurosci. 2020 Oct 29;46(1):E111-E118. (PMID: 33119491)
Psychopharmacology (Berl). 2016 Oct;233(21-22):3771-3778. (PMID: 27553824)
Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Feb;5(2):239-250. (PMID: 31892465)
J Neurosci. 2021 Jun 16;41(24):5243-5250. (PMID: 34001631)
Psychoneuroendocrinology. 2023 Feb;148:105998. (PMID: 36493660)
Addict Biol. 2020 Jul;25(4):e12802. (PMID: 31328850)
Nicotine Tob Res. 2011 Aug;13(8):751-5. (PMID: 21454914)
Neuropsychologia. 2021 Jul 16;157:107876. (PMID: 33930388)
Neuroimage. 2020 Jul 15;215:116841. (PMID: 32283274)
Neurosci Biobehav Rev. 2023 Oct;153:105355. (PMID: 37562654)
Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14811-6. (PMID: 20679212)
Neurosci Biobehav Rev. 2017 Dec;83:657-677. (PMID: 28864234)
Curr Psychiatry Rep. 2007 Oct;9(5):388-95. (PMID: 17915078)
J Exp Psychol Gen. 1999 Mar;128(1):78-87. (PMID: 10100392)
Front Behav Neurosci. 2014 Oct 09;8:353. (PMID: 25346669)
Behav Neurosci. 2009 Oct;123(5):1066-75. (PMID: 19824773)
Am J Drug Alcohol Abuse. 2019;45(1):51-66. (PMID: 30632802)
Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11238-E11247. (PMID: 30420496)
Drug Alcohol Depend. 2011 Apr 1;114(2-3):207-16. (PMID: 21109366)
Psychiatry Res. 2014 Mar 30;215(3):675-82. (PMID: 24434041)
Psychoneuroendocrinology. 2008 Jul;33(6):890-5. (PMID: 18403130)
Nat Rev Neurosci. 2009 Jun;10(6):410-22. (PMID: 19455173)
Psychol Addict Behav. 2016 Aug;30(5):607-612. (PMID: 27077444)
J Behav Med. 2005 Aug;28(4):325-33. (PMID: 16049631)
Addiction. 2017 Jan;112(1):51-62. (PMID: 27450931)
Trends Neurosci. 1999 Oct;22(10):422-6. (PMID: 10481183)
J Neurosci. 2014 Jan 15;34(3):932-40. (PMID: 24431451)
Am Psychol. 2016 Nov;71(8):670-679. (PMID: 27977239)
Neurosci Biobehav Rev. 2011 Apr;35(5):1291-301. (PMID: 21316391)
Psychol Inq. 2015;26(1):48-53. (PMID: 25780321)
Appl Psychol Health Well Being. 2024 Aug;16(3):1159-1177. (PMID: 38197215)
Front Psychol. 2014 Jun 24;5:617. (PMID: 25009514)
J Neurosci. 2011 May 4;31(18):6771-9. (PMID: 21543607)
Brain Res Bull. 2001 Feb;54(3):287-98. (PMID: 11287133)
Eur Addict Res. 2011;17(4):217-24. (PMID: 21606649)
Neuroscience. 2014 Apr 25;266:1-12. (PMID: 24508744)
Psychoneuroendocrinology. 2013 Jun;38(6):941-6. (PMID: 23063878)
Biol Psychol. 2013 Apr;93(1):1-8. (PMID: 23274170)
Psychol Addict Behav. 2007 Sep;21(3):328-37. (PMID: 17874883)
J Subst Abuse Treat. 2022 Jul;138:108749. (PMID: 35216868)
Grant Information: EN 906/6-1 Deutsche Forschungsgemeinschaft
Contributed Indexing: Keywords: addiction; delay discounting; fMRI; regulation of craving; smoking; stress
Substance Nomenclature: WI4X0X7BPJ (Hydrocortisone)
Entry Date(s): Date Created: 20260924 Date Completed: 20260924 Latest Revision: 20260927
Update Code: 20260927
PubMed Central ID: PMC13612162
DOI: 10.1111/adb.70190
PMID: 42785753
Βάση Δεδομένων: MEDLINE
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  Data: Regulation of craving (ROC) by focusing on long-term negative consequences of drug use has been shown to successfully reduce subjective craving. This process is supported by the dorsolateral prefrontal cortex (dlPFC), which exerts control over reward and value signals in the ventral striatum (VS) and ventromedial prefrontal cortex (vmPFC). As stress impairs cognitive control and addiction is characterized by altered value computations manifesting in delay discounting, we examined how these factors interact with ROC and its neural correlates to better understand the use of ROC in high-risk situations. Sixty-eight male smokers underwent a delay discounting task and either a stress (socially evaluated cold pressor task) or a control condition. They subsequently completed a ROC task during fMRI while focusing on (1) long-term negative consequences (LATER) versus (2) short-term positive consequences (NOW). We found lower subjective craving ratings and attenuated neural responses in the VS (t = 4.33, p = 0.012) and vmPFC (t = 5.79, p &amp;lt; 0.001), as well as higher activation in the dlPFC (t = 4.09, p = 0.038) in the LATER compared to the NOW strategy. Although no neural or behavioural difference in ROC was observed between stress and control groups, both individual stress (cortisol) and delay discounting were positively related to vmPFC activity (NOW &amp;gt; LATER). We replicated previous results on ROC. Importantly, the association of vmPFC signals with stress response and delay discounting suggests that enhancing ROC success may involve reinforcing changes in self-referentiality of future thoughts to subjective value of drug use.&lt;br /&gt; (&#169; 2026 The Author(s). Addiction Biology published by John Wiley &amp; Sons Ltd on behalf of Society for the Study of Addiction.)
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  Data: Nat Neurosci. 2023 Feb;26(2):316-325. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2236536243%22&quot;&gt;36536243)&lt;/searchLink&gt;&lt;br /&gt;JAMA Psychiatry. 2022 Jul 1;79(7):641-650. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2235648415%22&quot;&gt;35648415)&lt;/searchLink&gt;&lt;br /&gt;Psychopharmacology (Berl). 2006 Mar;184(3-4):577-88. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2216133128%22&quot;&gt;16133128)&lt;/searchLink&gt;&lt;br /&gt;Psychoneuroendocrinology. 2009 Jan;34(1):2-18. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2219041187%22&quot;&gt;19041187)&lt;/searchLink&gt;&lt;br /&gt;Eur Addict Res. 2012;18(3):103-9. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2222285929%22&quot;&gt;22285929)&lt;/searchLink&gt;&lt;br /&gt;Psychol Addict Behav. 2022 Dec;36(8):1012-1022. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2235175067%22&quot;&gt;35175067)&lt;/searchLink&gt;&lt;br /&gt;J Psychiatry Neurosci. 2020 Oct 29;46(1):E111-E118. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2233119491%22&quot;&gt;33119491)&lt;/searchLink&gt;&lt;br /&gt;Psychopharmacology (Berl). 2016 Oct;233(21-22):3771-3778. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2227553824%22&quot;&gt;27553824)&lt;/searchLink&gt;&lt;br /&gt;Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Feb;5(2):239-250. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2231892465%22&quot;&gt;31892465)&lt;/searchLink&gt;&lt;br /&gt;J Neurosci. 2021 Jun 16;41(24):5243-5250. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2234001631%22&quot;&gt;34001631)&lt;/searchLink&gt;&lt;br /&gt;Psychoneuroendocrinology. 2023 Feb;148:105998. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2236493660%22&quot;&gt;36493660)&lt;/searchLink&gt;&lt;br /&gt;Addict Biol. 2020 Jul;25(4):e12802. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2231328850%22&quot;&gt;31328850)&lt;/searchLink&gt;&lt;br /&gt;Nicotine Tob Res. 2011 Aug;13(8):751-5. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2221454914%22&quot;&gt;21454914)&lt;/searchLink&gt;&lt;br /&gt;Neuropsychologia. 2021 Jul 16;157:107876. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2233930388%22&quot;&gt;33930388)&lt;/searchLink&gt;&lt;br /&gt;Neuroimage. 2020 Jul 15;215:116841. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2232283274%22&quot;&gt;32283274)&lt;/searchLink&gt;&lt;br /&gt;Neurosci Biobehav Rev. 2023 Oct;153:105355. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2237562654%22&quot;&gt;37562654)&lt;/searchLink&gt;&lt;br /&gt;Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14811-6. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2220679212%22&quot;&gt;20679212)&lt;/searchLink&gt;&lt;br /&gt;Neurosci Biobehav Rev. 2017 Dec;83:657-677. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2228864234%22&quot;&gt;28864234)&lt;/searchLink&gt;&lt;br /&gt;Curr Psychiatry Rep. 2007 Oct;9(5):388-95. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2217915078%22&quot;&gt;17915078)&lt;/searchLink&gt;&lt;br /&gt;J Exp Psychol Gen. 1999 Mar;128(1):78-87. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210100392%22&quot;&gt;10100392)&lt;/searchLink&gt;&lt;br /&gt;Front Behav Neurosci. 2014 Oct 09;8:353. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2225346669%22&quot;&gt;25346669)&lt;/searchLink&gt;&lt;br /&gt;Behav Neurosci. 2009 Oct;123(5):1066-75. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2219824773%22&quot;&gt;19824773)&lt;/searchLink&gt;&lt;br /&gt;Am J Drug Alcohol Abuse. 2019;45(1):51-66. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2230632802%22&quot;&gt;30632802)&lt;/searchLink&gt;&lt;br /&gt;Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11238-E11247. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2230420496%22&quot;&gt;30420496)&lt;/searchLink&gt;&lt;br /&gt;Drug Alcohol Depend. 2011 Apr 1;114(2-3):207-16. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2221109366%22&quot;&gt;21109366)&lt;/searchLink&gt;&lt;br /&gt;Psychiatry Res. 2014 Mar 30;215(3):675-82. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2224434041%22&quot;&gt;24434041)&lt;/searchLink&gt;&lt;br /&gt;Psychoneuroendocrinology. 2008 Jul;33(6):890-5. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2218403130%22&quot;&gt;18403130)&lt;/searchLink&gt;&lt;br /&gt;Nat Rev Neurosci. 2009 Jun;10(6):410-22. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2219455173%22&quot;&gt;19455173)&lt;/searchLink&gt;&lt;br /&gt;Psychol Addict Behav. 2016 Aug;30(5):607-612. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2227077444%22&quot;&gt;27077444)&lt;/searchLink&gt;&lt;br /&gt;J Behav Med. 2005 Aug;28(4):325-33. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2216049631%22&quot;&gt;16049631)&lt;/searchLink&gt;&lt;br /&gt;Addiction. 2017 Jan;112(1):51-62. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2227450931%22&quot;&gt;27450931)&lt;/searchLink&gt;&lt;br /&gt;Trends Neurosci. 1999 Oct;22(10):422-6. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2210481183%22&quot;&gt;10481183)&lt;/searchLink&gt;&lt;br /&gt;J Neurosci. 2014 Jan 15;34(3):932-40. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2224431451%22&quot;&gt;24431451)&lt;/searchLink&gt;&lt;br /&gt;Am Psychol. 2016 Nov;71(8):670-679. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2227977239%22&quot;&gt;27977239)&lt;/searchLink&gt;&lt;br /&gt;Neurosci Biobehav Rev. 2011 Apr;35(5):1291-301. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2221316391%22&quot;&gt;21316391)&lt;/searchLink&gt;&lt;br /&gt;Psychol Inq. 2015;26(1):48-53. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2225780321%22&quot;&gt;25780321)&lt;/searchLink&gt;&lt;br /&gt;Appl Psychol Health Well Being. 2024 Aug;16(3):1159-1177. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2238197215%22&quot;&gt;38197215)&lt;/searchLink&gt;&lt;br /&gt;Front Psychol. 2014 Jun 24;5:617. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2225009514%22&quot;&gt;25009514)&lt;/searchLink&gt;&lt;br /&gt;J Neurosci. 2011 May 4;31(18):6771-9. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2221543607%22&quot;&gt;21543607)&lt;/searchLink&gt;&lt;br /&gt;Brain Res Bull. 2001 Feb;54(3):287-98. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2211287133%22&quot;&gt;11287133)&lt;/searchLink&gt;&lt;br /&gt;Eur Addict Res. 2011;17(4):217-24. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2221606649%22&quot;&gt;21606649)&lt;/searchLink&gt;&lt;br /&gt;Neuroscience. 2014 Apr 25;266:1-12. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2224508744%22&quot;&gt;24508744)&lt;/searchLink&gt;&lt;br /&gt;Psychoneuroendocrinology. 2013 Jun;38(6):941-6. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2223063878%22&quot;&gt;23063878)&lt;/searchLink&gt;&lt;br /&gt;Biol Psychol. 2013 Apr;93(1):1-8. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2223274170%22&quot;&gt;23274170)&lt;/searchLink&gt;&lt;br /&gt;Psychol Addict Behav. 2007 Sep;21(3):328-37. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2217874883%22&quot;&gt;17874883)&lt;/searchLink&gt;&lt;br /&gt;J Subst Abuse Treat. 2022 Jul;138:108749. (PMID: &lt;searchLink fieldCode=&quot;PM&quot; term=&quot;%2235216868%22&quot;&gt;35216868)&lt;/searchLink&gt;
– Name: GrantInfo
  Label: Grant Information
  Group: Grant
  Data: EN 906/6-1 Deutsche Forschungsgemeinschaft
– Name: SubjectMinor
  Label: Contributed Indexing
  Group:
  Data: &lt;i&gt;Keywords: &lt;/i&gt;addiction; delay discounting; fMRI; regulation of craving; smoking; stress
– Name: NumberCAS
  Label: Substance Nomenclature
  Group: ID
  Data: WI4X0X7BPJ (Hydrocortisone)
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  Data: &lt;i&gt;Date Created: &lt;/i&gt;20260924 &lt;i&gt;Date Completed: &lt;/i&gt;20260924 &lt;i&gt;Latest Revision: &lt;/i&gt;20260927
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  Group: Date
  Data: 20260927
– Name: PubmedCentralID
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  Data: PMC13612162
– Name: DOI
  Label: DOI
  Group: ID
  Data: 10.1111/adb.70190
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  Data: 42785753
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=cmedm&AN=42785753
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    Identifiers:
      – Type: doi
        Value: 10.1111/adb.70190
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e70190
    Subjects:
      – SubjectFull: Ventral Striatum physiopathology
        Type: general
      – SubjectFull: Ventral Striatum diagnostic imaging
        Type: general
      – SubjectFull: Hydrocortisone metabolism
        Type: general
      – SubjectFull: Dorsolateral Prefrontal Cortex physiopathology
        Type: general
      – SubjectFull: Dorsolateral Prefrontal Cortex diagnostic imaging
        Type: general
      – SubjectFull: Humans
        Type: general
      – SubjectFull: Male
        Type: general
      – SubjectFull: Magnetic Resonance Imaging
        Type: general
      – SubjectFull: Adult
        Type: general
      – SubjectFull: Young Adult
        Type: general
      – SubjectFull: Reward
        Type: general
      – SubjectFull: Delay Discounting physiology
        Type: general
      – SubjectFull: Craving physiology
        Type: general
      – SubjectFull: Stress, Psychological physiopathology
        Type: general
      – SubjectFull: Stress, Psychological psychology
        Type: general
      – SubjectFull: Prefrontal Cortex physiopathology
        Type: general
      – SubjectFull: Prefrontal Cortex diagnostic imaging
        Type: general
    Titles:
      – TitleFull: Regulation of Craving: Neural Correlates and the Role of Stress and Delay Discounting.
        Type: main
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      – PersonEntity:
          Name:
            NameFull: Nickel-Grenke S
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          Name:
            NameFull: Wüllhorst R
      – PersonEntity:
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            NameFull: Scherbaum S
      – PersonEntity:
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            NameFull: Schwarz K
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          Name:
            NameFull: Endrass T
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      – BibEntity:
          Dates:
            – D: 01
              M: 10
              Text: 2026 Oct
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1369-1600
          Numbering:
            – Type: volume
              Value: 31
            – Type: issue
              Value: 10
          Titles:
            – TitleFull: Addiction biology
              Type: main
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