Academic Journal
Balancing flexibility and ethical oversight: Japan's regulatory framework for human stem cell-based embryo model research.
| Τίτλος: | Balancing flexibility and ethical oversight: Japan's regulatory framework for human stem cell-based embryo model research. |
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| Συγγραφείς: | Kamisato A; Department of Medical Legal Research, National Center for Child Health and Development, Tokyo, Japan. Electronic address: kamisato-a@ncchd.go.jp., Akutsu H; Center for Regenerative Medicine, National Center for Child Health and Development, Tokyo, Japan. |
| Πηγή: | Stem cell reports [Stem Cell Reports] 2026 Oct 13; Vol. 21 (10), pp. 103085. Date of Electronic Publication: 2026 Sep 24. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: [Cambridge, MA] : Cell Press, c 2013- |
| Ιατρικοί όροι (MeSH): | Embryo Research*/ethics , Embryo Research*/legislation & jurisprudence , Human Embryonic Stem Cells*/cytology , Stem Cell Research*/ethics , Stem Cell Research*/legislation & jurisprudence , Models, Biological*, Humans ; Japan |
| Περίληψη: | Japan revised its national government guidelines in 2026 to regulate research on human stem cell-based embryo models (SCBEMs). Based on the view that current SCBEMs are distinct from human embryos, the framework adopts relatively flexible oversight while prohibiting reproductive use and allowing future revision as scientific advances emerge. (Copyright © 2026 The Author(s). Published by Elsevier Inc. All rights reserved.) |
| Competing Interests: | Declaration of interests The authors declare no competing interests. |
| References: | EMBO Rep. 2025 Jun;26(12):2973-2976. (PMID: 40425781) Stem Cell Res Ther. 2025 Aug 29;16(1):471. (PMID: 40877982) Nat Rev Mol Cell Biol. 2026 Mar;27(3):178-193. (PMID: 41486301) Hum Reprod. 2026 Jun 1;41(6):830-846. (PMID: 41875051) Cell. 2023 Aug 17;186(17):3548-3557. (PMID: 37595564) EMBO Rep. 2025 Apr;26(7):1682-1687. (PMID: 40087470) Cell Stem Cell. 2026 Jul 2;33(7):1062-1065. (PMID: 42392051) Nat Cell Biol. 2026 Apr;28(4):659-664. (PMID: 41951754) |
| Entry Date(s): | Date Created: 20260924 Date Completed: 20261013 Latest Revision: 20261022 |
| Update Code: | 20261022 |
| PubMed Central ID: | PMC13681318 |
| DOI: | 10.1016/j.stemcr.2026.103085 |
| PMID: | 42785306 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 2213-6711 |
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| DOI: | 10.1016/j.stemcr.2026.103085 |