Academic Journal
Monte Carlo evaluation of a novel hybrid-shielded gamma probe with integrated counting and emission direction-finding capabilities.
| Τίτλος: | Monte Carlo evaluation of a novel hybrid-shielded gamma probe with integrated counting and emission direction-finding capabilities. |
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| Συγγραφείς: | Kolcu OB; Istinye University, Istanbul, TR-34010, Türkiye., Yetkin T; Istinye University, Istanbul, TR-34010, Türkiye., Zengin AT; Istanbul Technical University, Istanbul, TR-34467, Türkiye., Iren E; Mimar Sinan Fine Arts University, Istanbul, TR-34380, Türkiye. |
| Πηγή: | Physics in medicine and biology [Phys Med Biol] 2026 Sep 29; Vol. 71 (19). Date of Electronic Publication: 2026 Sep 29. |
| Τύπος έκδοσης: | Journal Article; Evaluation Study |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: IOP Publishing Country of Publication: England NLM ID: 0401220 Publication Model: Electronic Cited Medium: Internet ISSN: 1361-6560 (Electronic) Linking ISSN: 00319155 NLM ISO Abbreviation: Phys Med Biol Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Bristol : IOP Publishing |
| Ιατρικοί όροι (MeSH): | Radiation Protection*/instrumentation , Scintillation Counting*/instrumentation , Monte Carlo Method* , Gamma Rays* |
| Περίληψη: | Objective.Gamma probes for sentinel lymph node localization usually work in counting mode only, with no information on the angular origin of detected gammas. Active-shielded designs that add emission direction finding reach about 95%-97% shielding effectiveness, below the >99% level of passive-shielded commercial probes. We propose and evaluate a hybrid-shielded gamma probe combining both capabilities.Approach.The module integrates a central GAGG(Ce) scintillator for counting, an asymmetric lead or sintered tungsten shielding layer, and an outer ring of GAGG(Ce) scintillators that provide passive attenuation and direction finding functionality. The scintillators are read out by asilicon photomultiplier array. We performed GEANT4 Monte Carlo simulations for99 mTc source. Sensitivity, spatial and angular resolution, and shielding effectiveness were characterized according to the NEMA NU3-2004 protocol in air and water, and direction-finding accuracy was assessed over a 360azimuthal scan with a centre-of-gravity (COG) estimator and a von Mises maximum-likelihood fit.Main results.Shielding effectiveness reachedwith the lead collimator andwith the sintered tungsten one, both within the range of passive-shielded commercial probes. Sensitivity at 10 mm in air was around 4560 cps MBq, with spatial and angular resolutions comparable to commercial devices. Over the 360scan, the mean absolute deviation of the estimated direction was 4.05COG and 4.55(maximum-likelihood), with a maximum below 7.2in both cases.Significance.Keeping shielding and directional sensing in separate elements allows each to be optimized independently. To our knowledge, this is the first gamma probe concept combining emission direction finding with shielding above 99%, which has been the main limitation of active-shielded designs. GAGG(Ce), not used in any commercial probe yet, is non-hygroscopic and well matched to silicon photomultipliers. These results motivate experimental prototyping and clinical validation. (Creative Commons Attribution license.) |
| Contributed Indexing: | Keywords: GEANT4; Gamma probe; Monte Carlo simulation; emission direction finding; hybrid shielding; sentinel LYMPH node localization |
| Entry Date(s): | Date Created: 20260918 Date Completed: 20260929 Latest Revision: 20260929 |
| Update Code: | 20260929 |
| DOI: | 10.1088/1361-6560/aea9e7 |
| PMID: | 42759556 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1361-6560 |
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| DOI: | 10.1088/1361-6560/aea9e7 |