Academic Journal
Monte Carlo-Based Optimization of Multi-Source Illumination for Photoacoustic Signal Generation in Human Gray-Matter Vessels.
| Τίτλος: | Monte Carlo-Based Optimization of Multi-Source Illumination for Photoacoustic Signal Generation in Human Gray-Matter Vessels. |
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| Συγγραφείς: | Tong J; School of Mathematics and Physics, Hebei University of Engineering, Handan, China., Han H; School of Mathematics and Physics, Hebei University of Engineering, Handan, China., Zhang Y; School of Mathematics and Physics, Hebei University of Engineering, Handan, China., Shen Y; School of Mathematics and Physics, Hebei University of Engineering, Handan, China., Wang Z; School of Mathematics and Physics, Hebei University of Engineering, Handan, China., Yang X; Institute of Acoustics, Chinese Academy of Sciences, Beijing, China. |
| Πηγή: | Journal of biophotonics [J Biophotonics] 2026 Sep; Vol. 19 (9), pp. e70364. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101318567 Publication Model: Print Cited Medium: Internet ISSN: 1864-0648 (Electronic) Linking ISSN: 1864063X NLM ISO Abbreviation: J Biophotonics Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Weinheim : Wiley-VCH |
| Ιατρικοί όροι (MeSH): | Photoacoustic Techniques*/methods , Gray Matter*/blood supply , Gray Matter*/diagnostic imaging , Blood Vessels*/diagnostic imaging , Monte Carlo Method* , Lighting*, Humans |
| Περίληψη: | Effective excitation of cerebrovascular photoacoustic signals is limited by superficial tissue attenuation and illumination geometry. This paper proposes a multi-source illumination evaluation method for gray-matter vessel targets based on Monte Carlo light transport and photoacoustic initial-pressure calculation using a simplified multilayer brain model for screening and a Tissue Probability Map (TPM) brain model for validation. The dual Collimated Gaussian source with 15° symmetric incidence along the Y direction performed best in the regular layered model, whereas the dual Pencil Array source with 20° symmetric incidence along the Y direction was optimal in the TPM model. These results suggest that regular layered models are suitable for preliminary screening, but the final illumination scheme should be revalidated under anatomical constraints. This study provides a theoretical reference for optimizing optical-source configurations in human brain photoacoustic imaging. (© 2026 Wiley‐VCH GmbH.) |
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| Contributed Indexing: | Keywords: Monte Carlo simulation; brain tissue; gray‐matter vessel; model‐transfer mismatch; multi‐source illumination; photoacoustic imaging; photoacoustic initial pressure |
| Entry Date(s): | Date Created: 20260917 Date Completed: 20260917 Latest Revision: 20260922 |
| Update Code: | 20260922 |
| PubMed Central ID: | PMC13584657 |
| DOI: | 10.1002/jbio.70364 |
| PMID: | 42752981 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1864-0648 |
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| DOI: | 10.1002/jbio.70364 |