Academic Journal
Psychosis Due to Lamotrigine Toxicity: Case Report.
| Τίτλος: | Psychosis Due to Lamotrigine Toxicity: Case Report. |
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| Συγγραφείς: | Nasr TS; Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN., Smith AC, Degen HE |
| Πηγή: | Journal of psychiatric practice [J Psychiatr Pract] 2026 Sep 01; Vol. 32 (5), pp. 298-299. Date of Electronic Publication: 2026 Sep 01. |
| Τύπος έκδοσης: | Journal Article; Case Reports |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 100901141 Publication Model: Electronic Cited Medium: Internet ISSN: 1538-1145 (Electronic) Linking ISSN: 15274160 NLM ISO Abbreviation: J Psychiatr Pract Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Philadelphia, PA : Lippincott Williams & Wilkins, c2000- |
| Ιατρικοί όροι (MeSH): | Psychoses, Substance-Induced*/etiology , Triazines*/adverse effects , Anticonvulsants*/adverse effects , Lamotrigine*, Humans ; Female ; Adult |
| Περίληψη: | Lamotrigine toxicity may be associated with a variety of nonspecific clinical findings, and rarely with psychosis. Many previous studies have reported that the use of lamotrigine with other agents, such as valproic acid, or an overdose of lamotrigine precipitated symptoms of lamotrigine toxicity. This case involved a 31-year-old woman who experienced dizziness, emesis, and psychosis after her lamotrigine prescription had recently been increased. These symptoms resolved when lamotrigine was held after the diagnosis of lamotrigine toxicity had been made. To our knowledge, this is a rare documented case of psychosis associated with lamotrigine toxicity, independent of intentional overdose or concurrent use of valproic acid. (Copyright © 2026 Wolters Kluwer Health, LLC. All rights reserved.) |
| Competing Interests: | The authors declare no conflicts of interest. |
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| Contributed Indexing: | Keywords: altered mental status; consultation; lamotrigine toxicity; psychiatry; psychosis |
| Substance Nomenclature: | U3H27498KS (Lamotrigine) 0 (Triazines) 0 (Anticonvulsants) |
| Entry Date(s): | Date Created: 20260914 Date Completed: 20260914 Latest Revision: 20260914 |
| Update Code: | 20260915 |
| DOI: | 10.1097/PRA.0000000000000950 |
| PMID: | 42735281 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1538-1145 |
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| DOI: | 10.1097/PRA.0000000000000950 |