Academic Journal
Agreement between Sirius Scheimpflug-Placido tomography and Anterion swept-source OCT in keratoconic eyes stratified by prior corneal cross-linking: a retrospective cross-sectional agreement study.
| Τίτλος: | Agreement between Sirius Scheimpflug-Placido tomography and Anterion swept-source OCT in keratoconic eyes stratified by prior corneal cross-linking: a retrospective cross-sectional agreement study. |
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| Συγγραφείς: | Erdogan K; Department of Ophthalmology, Division of Cornea, Erciyes University Medical Faculty, Kayseri, Turkey., Unlu M; Department of Ophthalmology, Division of Cornea, Erciyes University Medical Faculty, Kayseri, Turkey. drunlumetin@hotmail.com., Ozer F; Department of Ophthalmology, Nevsehir State Hospital, Nevsehir, Turkey. |
| Πηγή: | International ophthalmology [Int Ophthalmol] 2026 Sep 11; Vol. 46 (1). Date of Electronic Publication: 2026 Sep 11. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Kluwer Country of Publication: Netherlands NLM ID: 7904294 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2630 (Electronic) Linking ISSN: 01655701 NLM ISO Abbreviation: Int Ophthalmol Subsets: MEDLINE |
| Imprint Name(s): | Publication: Dordrecht : Kluwer Original Publication: The Hague, Junk. |
| Ιατρικοί όροι (MeSH): | Keratoconus*/diagnosis , Keratoconus*/drug therapy , Corneal Cross-Linking*/methods , Tomography, Optical Coherence*/methods , Cornea*/pathology, Corneal Topography/methods ; Photosensitizing Agents/therapeutic use ; Cross-Linking Reagents/therapeutic use ; Humans ; Retrospective Studies ; Female ; Adult ; Cross-Sectional Studies ; Male ; Young Adult ; Collagen ; Reproducibility of Results ; Adolescent |
| Περίληψη: | Aim: This study aims to assess the agreement between the Scheimpflug-Placido tomographer (Sirius) and the anterior-segment swept-source optical coherence tomography (Anterion) in evaluating anterior segment parameters separately in keratoconus (KC) patients with and without corneal cross-linking (CXL). Methods: A retrospective analysis was conducted on 108 eyes of patients with keratoconus (KC), divided into two groups according to previous corneal collagen cross-linking (CXL) status: eyes with prior CXL (wCXL group, n = 72) and eyes without CXL (woCXL group, n = 36). Evaluated parameters included anterior and posterior keratometric measurements, pachymetric measurements, anterior chamber parameters, corneal astigmatism, and corneal shape/elevation-related indices. Measurements from both devices were compared using Bland-Altman analysis, assessing fixed and proportional biases. Agreement between devices was interpreted based on the combination of absence of significant fixed bias, absence of proportional bias, and the width of the 95% limits of agreement (LoA). Results: In the wCXL group, anterior astigmatism (ant-Ast) and anterior best-fit toric ellipsoid (ant-BFT) demonstrated the most favorable bias characteristics. In the woCXL group, ant-Ast, ACD, posterior K1, and posterior Kmean showed favorable bias characteristics. Conclusions: Although ant-Ast and ant-BFT in the wCXL group and ACD, ant-Ast, posterior K1, and posterior Kmean in the woCXL group demonstrated no statistically significant fixed or proportional bias, the relatively wide LoA do not support interchangeable use of Sirius and Anterion for these measurements. (© 2026. The Author(s), under exclusive licence to Springer Nature B.V.) |
| Competing Interests: | Declarations. Conflict of interest: The authors declare no competing interests. Ethical approval: The research protocol received approval from the Erciyes University Local Ethics Committee (No:2024/180). Every participant provided their written consent to take part in the study. |
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| Contributed Indexing: | Keywords: Anterion device; Corneal cross-linking; Keratoconus; Sirius device |
| Substance Nomenclature: | 0 (Photosensitizing Agents) 0 (Cross-Linking Reagents) 9007-34-5 (Collagen) |
| Entry Date(s): | Date Created: 20260911 Date Completed: 20260911 Latest Revision: 20261008 |
| Update Code: | 20261008 |
| DOI: | 10.1007/s10792-026-04227-z |
| PMID: | 42726338 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1573-2630 |
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| DOI: | 10.1007/s10792-026-04227-z |