Sharing is not caring: Near-germline and polyreactive memory B cells in primary dengue.

Bibliographic Details
Title: Sharing is not caring: Near-germline and polyreactive memory B cells in primary dengue.
Authors: Lowman KE; Viral Epidemiology and Immunity Unit, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Aogo RA; Viral Epidemiology and Immunity Unit, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Katzelnick LC; Viral Epidemiology and Immunity Unit, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address: leah.katzelnick@nih.gov.
Source: Cell reports [Cell Rep] 2026 Sep 22; Vol. 45 (9), pp. 117956. Date of Electronic Publication: 2026 Sep 09.
Publication Type: Journal Article
Language: English
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Imprint Name(s): Original Publication: [Cambridge, MA] : Cell Press, c 2012-
MeSH Terms: Dengue*/immunology , Dengue Virus*/immunology , Memory B Cells*/immunology , B-Lymphocytes*/immunology , Immunologic Memory*, Humans
Abstract: Verdonckt et al.1 characterize B cell receptor repertoires after dengue virus 1 challenge and observe atypical primary responses enriched for polyreactive and public, near-germline memory B cell sequences containing dengue-associated motifs that could represent an inherent constraint of dengue immunobiology.
(Published by Elsevier Inc.)
Competing Interests: Declaration of interests The authors declare no competing interests.
Entry Date(s): Date Created: 20260909 Date Completed: 20260924 Latest Revision: 20260924
Update Code: 20260924
DOI: 10.1016/j.celrep.2026.117956
PMID: 42715094
Database: MEDLINE
Description
ISSN:2211-1247
DOI:10.1016/j.celrep.2026.117956