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Long-term cancer trends among male Taiwanese farmers: an age-period-cohort analysis (2000-2023).

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Τίτλος: Long-term cancer trends among male Taiwanese farmers: an age-period-cohort analysis (2000-2023).
Συγγραφείς: Francis LM; Department of Environmental, Occupational, and Geospatial Health Sciences, City University of New York (CUNY) Graduate School of Public Health & Health Policy, New York, USA., Soliman AS; Department of Community Health and Social Medicine, City University of New York (CUNY) School of Medicine, New York, USA., Wu LY; Department of Public Health, College of Public Health, China Medical University, No. 100, Sec. 1, Jingmao Rd., Beitun Dist., Taichung City, Taiwan., Chung CJ; Department of Public Health, College of Public Health, China Medical University, No. 100, Sec. 1, Jingmao Rd., Beitun Dist., Taichung City, Taiwan. cjchung@mail.cmu.edu.tw.; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan. cjchung@mail.cmu.edu.tw.
Πηγή: International archives of occupational and environmental health [Int Arch Occup Environ Health] 2026 Sep 06; Vol. 99 (7). Date of Electronic Publication: 2026 Sep 06.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7512134 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1246 (Electronic) Linking ISSN: 03400131 NLM ISO Abbreviation: Int Arch Occup Environ Health Subsets: MEDLINE
Imprint Name(s): Original Publication: Berlin, New York : Springer-Verlag.
Ιατρικοί όροι (MeSH): Neoplasms*/epidemiology , Farmers*/statistics & numerical data , Occupational Exposure*/adverse effects , Agricultural Workers' Diseases*/epidemiology, Taiwan/epidemiology ; Lung Neoplasms/epidemiology ; Humans ; Male ; Middle Aged ; Aged ; Adult ; Aged, 80 and over ; Incidence ; Young Adult ; Adolescent ; Cohort Studies ; Age Factors
Περίληψη: Purpose: Male farmers are frequently exposed to various environmental and occupational hazards that may be related to cancer risk. Long-term cancer incidence trends in male farmers in Taiwan remain unclear. This study examined temporal trends in cancer incidence among male farmers over a 24-year period.
Methods: Using Taiwan's Longitudinal Health Insurance Database of Patients with Catastrophic Illnesses (2000-2023), we conducted a nationwide cohort study of agricultural workers whose aged 15-84 (N= 2,426,531). ICD-O-3 and the corresponding ICD-9-CM and ICD-10-CM codes from the Taiwan Cancer Registry Annual Report were used to identify annually incident cancer cases. Age-standardized incidence rates, age-standardized rate ratios, and age-standardized incidence ratios were calculated. A Joinpoint regression and age-period-cohort model were used to identify and examine temporal trends across the study period.
Results: Overall cancer incidence was higher among male farmers compared to the male general population, with an increasing temporal trend from 2000 to 2023. Lip and lung cancers showed a significantly increased annual average percentage change (AAPC) value, age effect, period effect, and cohort effect for the study period, while liver cancer showed a decreasing AAPC, period effect, and cohort effect, with an increasing age effect over the entire study period.
Conclusion: This study provides evidence that lung and lip cancer incidence among male farmers increased significantly over the study period, while liver cancer decreased. As exposure varies by agricultural activity and farm type, further research is needed to identify specific exposures that are related to the higher risk of cancer in this population.
(© 2026. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Competing Interests: Declarations. Conflict of interest: The authors declare that they have no conflict of interest. Ethical approval: The study was approved by the China Medical University and Hospital Research Ethics Committee (CRREC-109-018). Consent to participate: Not applicable. Consent for publication: Not applicable.
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Grant Information: R25 CA112383 Cancer Epidemiology Education in Special Populations Fellowship; MOST 108-2221-E-039-009-MY3 Ministry of Science and Technology, Taiwan; CMU108-MF-94 China Medical University, Taiwan
Contributed Indexing: Keywords: Age-period-cohort; Agricultural exposures; Cancer; Farmers; Joinpoint regression; Taiwan
Entry Date(s): Date Created: 20260906 Date Completed: 20260906 Latest Revision: 20260925
Update Code: 20260925
DOI: 10.1007/s00420-026-02235-1
PMID: 42701910
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1432-1246
DOI:10.1007/s00420-026-02235-1