Academic Journal
An integrated litmus test platform for low-background detection and photothermal inactivation of Salmonella typhimurium via HCR-urease signal amplification.
| Τίτλος: | An integrated litmus test platform for low-background detection and photothermal inactivation of Salmonella typhimurium via HCR-urease signal amplification. |
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| Συγγραφείς: | Kang Q; Tianjin Key Laboratory of Food Quality and Health, College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China., Lin T; Tianjin Key Laboratory of Food Quality and Health, College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China., Jiao J; Tianjin Key Laboratory of Food Quality and Health, College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China., Du X; Tianjin Key Laboratory of Food Quality and Health, College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China. Electronic address: xjdu@tust.edu.cn., Wang S; Tianjin Key Laboratory of Food Science and Health, School of Medicine, Nankai University, Tianjin 300071, China. Electronic address: wangshuo@nankai.edu.cn. |
| Πηγή: | Food chemistry [Food Chem] 2026 Oct 30; Vol. 527, pp. 150935. Date of Electronic Publication: 2026 Aug 27. |
| Τύπος έκδοσης: | Journal Article; Evaluation Study |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE |
| Imprint Name(s): | Publication: Barking : Elsevier Applied Science Publishers Original Publication: Barking, Eng., Applied Science Publishers. |
| Ιατρικοί όροι (MeSH): | Salmonella typhimurium*/genetics , Salmonella typhimurium*/isolation & purification , Salmonella typhimurium*/radiation effects , Salmonella typhimurium*/chemistry , Salmonella typhimurium*/enzymology , Salmonella typhimurium*/growth & development , Biosensing Techniques*/methods , Biosensing Techniques*/instrumentation , Urease*/chemistry , Bacterial Proteins*/genetics, Food Contamination/analysis ; Colorimetry/methods ; Nucleic Acid Hybridization/methods ; Food Microbiology/methods |
| Περίληψη: | Herein, we propose a novel "low-background" biosensing platform integrating magnetic separation and hybridization chain reaction (HCR) for signal amplification, enabling ratiometric colorimetric detection and visual observation of S. typhimurium. In the presence of S. typhimurium, specific aptamer recognition triggers the HCR to couple the urease-labeled DNA to the HCR reporting system, ultimately generating a ratiometric colorimetric response upon enrichment by Fe (Copyright © 2026 Elsevier Ltd. All rights reserved.) |
| Competing Interests: | Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| Contributed Indexing: | Keywords: Hybridization chain reaction; Inactivation; Litmus-based biosensing; Ratiometric colorimetric; S. typhimurium |
| Substance Nomenclature: | EC 3.5.1.5 (Urease) 0 (Bacterial Proteins) |
| Entry Date(s): | Date Created: 20260829 Date Completed: 20261016 Latest Revision: 20261016 |
| Update Code: | 20261016 |
| DOI: | 10.1016/j.foodchem.2026.150935 |
| PMID: | 42667770 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1873-7072 |
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| DOI: | 10.1016/j.foodchem.2026.150935 |