Academic Journal
[Research on blood viscoelasticity detection based on electrowetting technology].
| Τίτλος: | [Research on blood viscoelasticity detection based on electrowetting technology]. |
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| Συγγραφείς: | Wang C; School of Precision Instrument and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, P. R. China., Huo W; School of Precision Instrument and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, P. R. China., Yang L; Autobio Labtec Instruments Co. Ltd., Zhengzhou 450016, P. R. China., Huang X; School of Precision Instrument and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, P. R. China., Yang W; Autobio Labtec Instruments Co. Ltd., Zhengzhou 450016, P. R. China. |
| Πηγή: | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi [Sheng Wu Yi Xue Gong Cheng Xue Za Zhi] 2026 Aug 25; Vol. 43 (4), pp. 777-783. |
| Τύπος έκδοσης: | English Abstract; Journal Article |
| Γλώσσα: | Chinese |
| Στοιχεία περιοδικού: | Publisher: Sichuan Sheng sheng wu yi xue gong cheng xue hui Country of Publication: China NLM ID: 9426398 Publication Model: Print Cited Medium: Print ISSN: 1001-5515 (Print) Linking ISSN: 10015515 NLM ISO Abbreviation: Sheng Wu Yi Xue Gong Cheng Xue Za Zhi Subsets: MEDLINE |
| Imprint Name(s): | Publication: Chengdu : Sichuan Sheng sheng wu yi xue gong cheng xue hui Original Publication: Chengdu : Sichuan Sheng sheng wu yi xue gong cheng xue hui : Hua xi yi ke da xue : Chengdu ke ji da xue |
| Ιατρικοί όροι (MeSH): | Electrowetting*/methods , Blood Coagulation*/physiology , Blood Viscosity*, Humans ; Elasticity ; Models, Theoretical |
| Περίληψη: | Parameters related to coagulation function are key clinical biomarker reflecting the coagulation status of the human blood system. The disorder of coagulation function could lead to multiple diseases such as hemophilia and ischemic stroke. Blood viscoelasticity can effectively characterize the rheological variations during blood coagulation, thus enabling comprehensive assessment of coagulation function. In this paper, electrowetting technology was adopted to develop the detection approach for blood viscoelasticity. A dynamic mathematical model of the detection system was established, and the core influencing factors of the detection system were deduced. The effects of critical parameters such as driving voltage, excitation frequency and dielectric layer thickness on detection performance were investigated systematically. The results indicate that the above parameters significantly affect the operating performance of the detection system. Optimized matching of system parameters can effectively improve the stability and detection accuracy of the system. Conclusively, the electrowetting based method achieves high-precision measurement of blood viscoelasticity, which provides a novel technical scheme for coagulation detection. |
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| Contributed Indexing: | Keywords: Detection method; Electrowetting; Stability and reliability; Viscoelasticity Local Abstract: [Publisher, Chinese] 凝血功能相关检测参数是评估血液系统凝血状态的重要临床指标，人体凝血功能异常会导致如血友病、脑卒中等多种疾病发生。其中，血液黏弹性用于表征凝血生化反应过程中血液流变物理特性的演变规律，能够对凝血功能进行全面评估。本文采用电润湿技术对血液黏弹性的检测方法进行了研究，构建了检测系统的动力学数学模型，推导出影响检测性能的影响因子，探究了系统的激励电压、激励频率及介电层厚度等系统参数对检测系统的影响规律。结果表明，系统参数对检测系统的性能影响比较显著，合理地选择参数有助于提升系统的稳定性与准确性。综合本文研究结果表明，基于电润湿技术的血液黏弹性检测方法，能够较好地实现凝血功能的检测，为凝血检测提供了一种新的路径。. |
| Entry Date(s): | Date Created: 20260827 Date Completed: 20260827 Latest Revision: 20260829 |
| Update Code: | 20260829 |
| PubMed Central ID: | PMC13519824 |
| DOI: | 10.7507/1001-5515.202508032 |
| PMID: | 42656109 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1001-5515 |
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| DOI: | 10.7507/1001-5515.202508032 |