Academic Journal
Inhibitory effects of surface pre-reacted glass-ionomer eluate on Candida albicans and commensal oral streptococci dual-species biofilm.
| Τίτλος: | Inhibitory effects of surface pre-reacted glass-ionomer eluate on Candida albicans and commensal oral streptococci dual-species biofilm. |
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| Συγγραφείς: | Fujishima K; Department of Preventive Dentistry, Kagoshima University Graduate School of Medicine and Dental Sciences., Hoshika T; Department of Restorative Dentistry and Endodontology, Kagoshima University Graduate School of Medicine and Dental Sciences., Watanabe A; Department of Oral Health Care and Rehabilitation, Tokushima University Graduate School of Biomedical Sciences., Oku Y; Department of Preventive Dentistry, Kagoshima University Graduate School of Medicine and Dental Sciences., Kudo Y; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences., Nishitani Y; Department of Restorative Dentistry and Endodontology, Kagoshima University Graduate School of Medicine and Dental Sciences., Tamaki N; Department of Preventive Dentistry, Kagoshima University Graduate School of Medicine and Dental Sciences. |
| Πηγή: | Dental materials journal [Dent Mater J] 2026 Sep 25; Vol. 45 (5), pp. 633-638. Date of Electronic Publication: 2026 Aug 26. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Japanese Society for Dental Materials and Devices Country of Publication: Japan NLM ID: 8309299 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1881-1361 (Electronic) Linking ISSN: 02874547 NLM ISO Abbreviation: Dent Mater J Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Tokyo-to : Japanese Society for Dental Materials and Devices, [1982?- |
| Ιατρικοί όροι (MeSH): | Biofilms*/drug effects , Candida albicans*/drug effects , Streptococcus mutans*/drug effects , Acrylic Resins*/pharmacology , Acrylic Resins*/chemistry , Streptococcus*/drug effects, Oxidative Stress/drug effects ; Surface Properties ; Humans ; Silicon Dioxide |
| Περίληψη: | Surface pre-reacted glass-ionomer (S-PRG) fillers, a bioactive material, possess various biological functions. Various studies have investigated the bioactive effects of S-PRG fillers; however, their effects on biofilms formed by multiple microorganisms remain unclear. Recently, several cases of rampant caries onset and severe caries in childhood caused by coinfections with cariogenic bacteria and commensal oral fungi have been reported. This study evaluated the effects of S-PRG eluate on complex biofilms involved in the onset of rampant and severe caries. The amounts of biofilm formed by co-culturing cariogenic bacteria and fungus was suppressed in a concentration-dependent manner by the S-PRG eluate. Furthermore, intracellular oxidative stress increased in proportion to the S-PRG eluate. The results of this study suggest that oxidative stress generated by S-PRG eluate suppresses the formation of complex microbial biofilms. |
| Contributed Indexing: | Keywords: Biofilm; Candida albicans; Streptococcus mutans; Surface pre-reacted glass-ionomer (S-PRG) eluate |
| Substance Nomenclature: | 0 (Acrylic Resins) 0 (glass ionomer) 7631-86-9 (Silicon Dioxide) |
| Entry Date(s): | Date Created: 20260826 Date Completed: 20260927 Latest Revision: 20260927 |
| Update Code: | 20260928 |
| DOI: | 10.4012/dmj.2026-127 |
| PMID: | 42649018 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1881-1361 |
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| DOI: | 10.4012/dmj.2026-127 |