Cepharanthine-mediated photodynamic inactivation and active gelatin packaging for pork preservation.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος: Cepharanthine-mediated photodynamic inactivation and active gelatin packaging for pork preservation.
Συγγραφείς: Yang L; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China., Su K; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China., Guo Z; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China., Li B; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China., Wang Y; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China., Guo Z; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China., Wang J; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China., Shi S; College of Chemistry & Pharmacy, Northwest A&F University, Yangling, Shaanxi 712100, China., Li S; Mengniu Hi-Tech Dairy Product Beijing Co., Ltd., Beijing, China; Inner Mongolia Mengniu Dairy Industry Co., Ltd., Hohhot, Inner Mongolia, China. Electronic address: lishusen@mengniu.cn., Su S; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China; Mengniu Hi-Tech Dairy Product Beijing Co., Ltd., Beijing, China; Inner Mongolia Mengniu Dairy Industry Co., Ltd., Hohhot, Inner Mongolia, China. Electronic address: sushengpeng@mengniu.cn., Zhang W; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, China. Electronic address: zhangwt@nwsuaf.edu.cn.
Πηγή: Food research international (Ottawa, Ont.) [Food Res Int] 2026 Oct 31; Vol. 242 (Pt 5), pp. 120236. Date of Electronic Publication: 2026 Aug 03.
Τύπος έκδοσης: Journal Article
Γλώσσα: English
Στοιχεία περιοδικού: Publisher: Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science Country of Publication: Canada NLM ID: 9210143 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7145 (Electronic) Linking ISSN: 09639969 NLM ISO Abbreviation: Food Res Int Subsets: MEDLINE
Imprint Name(s): Original Publication: Ottawa, Ontario, Canada : Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science, c1992-
Ιατρικοί όροι (MeSH): Gelatin*/chemistry , Food Preservation*/methods , Food Packaging*/methods , Benzylisoquinolines*/pharmacology , Photosensitizing Agents*/pharmacology , Red Meat*/microbiology, Staphylococcus aureus/drug effects ; Staphylococcus aureus/radiation effects ; Staphylococcus aureus/growth & development ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/growth & development ; Pseudomonas aeruginosa/radiation effects ; Anti-Bacterial Agents/pharmacology ; Food Microbiology/methods ; Microbial Viability/drug effects ; Food Irradiation/methods ; Animals ; Benzodioxoles ; Swine ; Hydrogen-Ion Concentration
Περίληψη: Photodynamic inactivation (PDI) offers a green, non-thermal and sustainable strategy for controlling foodborne pathogens and spoilage microorganisms in animal-derived foods, and natural products are increasingly being explored as photosensitizers. Here, we identify the previously underexplored photodynamic antibacterial activity of the natural alkaloid cepharanthine (CEP). SOSG fluorescence increased 6.88-fold after 10 min of irradiation, suggesting that CEP-mediated bacterial inactivation was predominantly associated with 1O2. Viable-count assays showed that CEP completely inactivated Staphylococcus aureus and Pseudomonas aeruginosa within 40 and 60 min, respectively. Its PDI activity was retained in 10% reconstituted milk without significant changes in pH or lipid oxidation. Incorporation of CEP into gelatin (Gel) films improved ultraviolet shielding, water-vapour barrier properties and mechanical strength. When applied to pork at 4 °C, CEP-Gel films markedly suppressed microbial growth, limiting total viable counts to 4.65 log CFU/g on day 12 compared with 7.50 log CFU/g in the control group. The films also delayed increases in pH, TVB-N, TBARS and weight loss. CEP-Gel significantly delayed microbial growth, lipid oxidation and protein degradation during the 12-day refrigerated storage period. Overall, this study expands the functional scope of CEP and establishes a promising strategy for the sustainable preservation of animal-derived foods.
(Copyright © 2026 Elsevier Ltd. All rights reserved.)
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Contributed Indexing: Keywords: Animal-derived food preservation; Cepharanthine; Photodynamic inactivation; Pseudomonas aeruginosa; Staphylococcus aureus
Substance Nomenclature: 7592YJ0J6T (cepharanthine)
9000-70-8 (Gelatin)
0 (Benzodioxoles)
0 (Benzylisoquinolines)
0 (Anti-Bacterial Agents)
0 (Photosensitizing Agents)
Entry Date(s): Date Created: 20260824 Date Completed: 20260824 Latest Revision: 20260824
Update Code: 20260825
DOI: 10.1016/j.foodres.2026.120236
PMID: 42637380
Βάση Δεδομένων: MEDLINE
Περιγραφή
ISSN:1873-7145
DOI:10.1016/j.foodres.2026.120236