Academic Journal
Accelerated organelle movements can indirectly affect the motility of other organelles in plant cells.
| Τίτλος: | Accelerated organelle movements can indirectly affect the motility of other organelles in plant cells. |
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| Συγγραφείς: | Gu JM; Department of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996-1939, USA., Keith A; Department of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996-1939, USA., Smith K; Department of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996-1939, USA., Nebenführ A; Department of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996-1939, USA. |
| Πηγή: | Journal of cell science [J Cell Sci] 2026 Sep 15; Vol. 139 (18). Date of Electronic Publication: 2026 Sep 25. |
| Τύπος έκδοσης: | Journal Article |
| Γλώσσα: | English |
| Στοιχεία περιοδικού: | Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9137 (Electronic) Linking ISSN: 00219533 NLM ISO Abbreviation: J Cell Sci Subsets: MEDLINE |
| Imprint Name(s): | Publication: Cambridge : Company of Biologists Original Publication: London. |
| Ιατρικοί όροι (MeSH): | Nicotiana*/metabolism , Nicotiana*/cytology , Organelles*/metabolism , Plant Cells*/metabolism, Peroxisomes/metabolism ; Myosins/metabolism ; Actin Cytoskeleton/metabolism ; Microtubules/metabolism ; Mitochondria/metabolism ; Golgi Apparatus/metabolism ; Endoplasmic Reticulum/metabolism ; Movement ; Cytoplasmic Streaming |
| Περίληψη: | Organelle movements in plants are driven by myosin XI motors moving along the actin filament cytoskeleton. Several experiments have suggested that indirect effects such as organelle-organelle interactions or hydrodynamic flow might be responsible for organelle movements. To test these models, we altered the motile behavior of specific organelles in Nicotiana benthamiana leaf epidermal cells and examined the effects of these perturbations on other organelles. Recruiting myosins to organelles with 'Booster' constructs resulted in significant increases of linear motions, whereas binding organelles to cortical microtubules with 'Anchor' constructs lead to diminished movements of the targeted mitochondria, peroxisomes and ER, respectively. We did not observe consistent effects of Anchor constructs on non-targeted organelles. Mitochondrial Boosters increased the motility of all tested organelles, presumably by leading to a reorganization of actin filaments. By contrast, ER Boosters resulted in enhanced movements for only Golgi stacks and peroxisomes, suggesting a specific interaction between these organelles. Collectively, this novel engineering approach to modify the movements of specific organelles demonstrates that organelle motility in plant cells can occur independently but nevertheless is coordinated between different types of organelles. (© 2026. Published by The Company of Biologists.) |
| Competing Interests: | Competing interests The authors declare no competing or financial interests. |
| Grant Information: | 1715794 Division of Molecular and Cellular Biosciences; MCB-1715794 National Science Foundation; University of Tennessee at Knoxville |
| Contributed Indexing: | Keywords: Actin filaments; Cytoplasmic streaming; Myosin XI; Organelle movements |
| Substance Nomenclature: | EC 3.6.4.1 (Myosins) |
| Entry Date(s): | Date Created: 20260824 Date Completed: 20260925 Latest Revision: 20260925 |
| Update Code: | 20260925 |
| DOI: | 10.1242/jcs.264573 |
| PMID: | 42634869 |
| Βάση Δεδομένων: | MEDLINE |
| ISSN: | 1477-9137 |
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| DOI: | 10.1242/jcs.264573 |