Non-Human Primates as Sentinels and Reservoirs of Emerging Zoonotic Diseases in Indonesia: A One Health Perspective on Pathogen Spillover, Surveillance Gaps, and Regulatory Frameworks.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Τίτλος:	Non-Human Primates as Sentinels and Reservoirs of Emerging Zoonotic Diseases in Indonesia: A One Health Perspective on Pathogen Spillover, Surveillance Gaps, and Regulatory Frameworks.
Συγγραφείς:	Sophian A; The Indonesian Food and Drug Authority (BPOM), Jakarta, Indonesia.
Πηγή:	Journal of medical primatology [J Med Primatol] 2026 Oct; Vol. 55 (5), pp. e70101.
Τύπος έκδοσης:	Journal Article; Review
Γλώσσα:	English
Στοιχεία περιοδικού:	Publisher: Wiley Country of Publication: Denmark NLM ID: 0320626 Publication Model: Print Cited Medium: Internet ISSN: 1600-0684 (Electronic) Linking ISSN: 00472565 NLM ISO Abbreviation: J Med Primatol Subsets: MEDLINE
Imprint Name(s):	Publication: Copenhagen : Wiley Original Publication: Basel, New York, Karger.
Ιατρικοί όροι (MeSH):	Zoonoses/epidemiology , Zoonoses/microbiology , Disease Reservoirs/veterinary , Communicable Diseases, Emerging/epidemiology , Communicable Diseases, Emerging/veterinary , Primate Diseases/epidemiology , Primate Diseases/microbiology , Sentinel Surveillance/veterinary , One Health* , Primates* , Sentinel Species*, Indonesia/epidemiology ; Animals ; Humans ; Wildlife Trade
Περίληψη:	Background and Aims: Indonesia harbors extraordinary non-human primate (NHP) diversity, yet deforestation, ecotourism, illegal wildlife trade, and urban encroachment are intensifying human-NHP contact, elevating pathogen spillover risk. This review synthesizes evidence on NHP-associated zoonoses within a One Health framework and proposes an integrated biosurveillance roadmap. Methods: A structured search of PubMed, Scopus, and Web of Science (2000-2025), informed by the PRISMA-ScR framework and using pre-specified host, geographic, and pathogen search terms, was conducted and supplemented by grey literature from WHO, FAO, BPOM, and Indonesia's Ministry of Health. Results: Five priority zoonotic pathogen categories were identified: Plasmodium knowlesi malaria, Macacine alphaherpesvirus 1 (Herpes B virus), simian foamy virus, Mycobacterium tuberculosis complex, and zoonotic gastrointestinal parasites. Surveillance capacity is fragmented and NHP-specific pathogen monitoring is absent from national systems. Conclusions: NHP-derived zoonoses represent a growing public health threat in Indonesia. A NHP-inclusive One Health surveillance system integrating molecular diagnostics, geographic information systems, and cross-sectoral regulatory coordination is urgently needed. (© 2026 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
References:	MMWR Morb Mortal Wkly Rep. 2024 Feb 22;73(7):145-148. (PMID: 38386802) Lancet. 2004 Mar 27;363(9414):1017-24. (PMID: 15051281) J Virol. 1999 Mar;73(3):1747-55. (PMID: 9971751) J Travel Med. 2009 Jul-Aug;16(4):229-32. (PMID: 19674260) BMC Med Res Methodol. 2018 Nov 19;18(1):143. (PMID: 30453902) Infect Immun. 2003 Oct;71(10):5831-44. (PMID: 14500505) Narra J. 2023 Dec;3(3):e257. (PMID: 38455621) Acta Parasitol. 2025 Feb 10;70(1):59. (PMID: 39928186) Emerg Infect Dis. 2002 Aug;8(8):789-95. (PMID: 12141963) Clin Microbiol Infect. 2012 Jun;18(6):521-7. (PMID: 22448813) J Virol. 2004 Mar;78(6):2780-9. (PMID: 14990698) Emerg Infect Dis. 2005 Jul;11(7):1028-35. (PMID: 16022776) Emerg Infect Dis. 2025 Apr;31(4):741-750. (PMID: 40133045) Folia Primatol (Basel). 2021;92(5-6):296-305. (PMID: 34695831) Nature. 2008 Feb 21;451(7181):990-3. (PMID: 18288193) Vet World. 2025 Jun;18(6):1527-1539. (PMID: 40689178) New Microbes New Infect. 2024 May 07;60-61:101422. (PMID: 38765002) Parasit Vectors. 2020 Sep 15;13(1):472. (PMID: 32933567) Viruses. 2023 Oct 13;15(10):. (PMID: 37896863) Nat Med. 2020 Apr;26(4):450-452. (PMID: 32284615) Clin Microbiol Rev. 2013 Apr;26(2):165-84. (PMID: 23554413) Clin Infect Dis. 2002 Nov 15;35(10):1191-203. (PMID: 12410479) Trop Med Int Health. 2005 Dec;10(12):1305-14. (PMID: 16359412) Parasit Vectors. 2022 Jul 18;15(1):258. (PMID: 35850777) Ann Intern Med. 2018 Oct 2;169(7):467-473. (PMID: 30178033) Emerg Infect Dis. 2003 Feb;9(2):246-50. (PMID: 12603998) Sci Rep. 2020 Oct 7;10(1):16759. (PMID: 33028865) Travel Med Infect Dis. 2010 May;8(3):169-75. (PMID: 20541137) Curr Biol. 2017 Nov 20;27(22):3487-3498.e10. (PMID: 29103940) Clin Infect Dis. 2008 Jan 15;46(2):165-71. (PMID: 18171245) J Exp Med. 1934 Jan 31;59(2):115-36. (PMID: 19870235) Am J Primatol. 2024 Mar;86(3):e23547. (PMID: 37667504) Nature. 2007 May 17;447(7142):279-83. (PMID: 17507975) Am J Primatol. 2005 Jun;66(2):197-204. (PMID: 15940713) Emerg Infect Dis. 2008 Aug;14(8):1200-8. (PMID: 18680642) Vet World. 2025 Nov;18(11):3651-3669. (PMID: 41472754)
Contributed Indexing:	Keywords: Macaca fascicularis; Indonesia; herpes B virus; non‐human primates; one health; pathogen spillover; plasmodium knowlesi; regulatory framework; surveillance; zoonotic diseases
Entry Date(s):	Date Created: 20260820 Date Completed: 20260820 Latest Revision: 20260822
Update Code:	20260822
PubMed Central ID:	PMC13490617
DOI:	10.1111/jmp.70101
PMID:	42619011
Βάση Δεδομένων:	MEDLINE

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ISSN:	1600-0684
DOI:	10.1111/jmp.70101